| Cambridge Hygienist Limited | Health & social care | 2023 |
| Cambridge Ice Skating Club Limited | Arts & recreation | 2025 |
| Cambridge ICT Limited | Information & communication | 2001 |
| Cambridge Ideas Limited | Information & communication | 2009 |
| Cambridge Imaging Holdings Limited | Professional & scientific | 2020 |
| Cambridge Imaging Solutions Ltd | Information & communication | 2015 |
| Cambridge Immersive Innovations Studio Ltd | Information & communication | 2023 |
| Cambridge Imprint 2025 Limited | Wholesale & retail | 2025 |
| Cambridge Imprint LLP | | 2013 |
| Cambridge in America (UK) Limited | Administrative & support | 2009 |
| Cambridge Index Ltd | Professional & scientific | 2015 |
| Cambridge Indigo Design (2011) Ltd | Professional & scientific | 2011 |
| Cambridge Indoor Cycling Limited | Arts & recreation | 2022 |
| Cambridge Industrial Design Limited | Professional & scientific | 2013 |
| Cambridge Industrial Innovation Ecosystem Research Center Ltd | Administrative & support | 2025 |
| Cambridge Industrialisation Ltd | Professional & scientific | 2026 |
| Cambridge Industry College Limited | Education | 2016 |
| Cambridge Inference Ltd | Administrative & support | 2023 |
| Cambridge Inn Limited | Real estate | 2016 |
| Cambridge Inner Game Leadership Ltd | Professional & scientific | 2015 |
| Cambridge Innovation Capital II (USD) LP | | 2020 |
| Cambridge Innovation Capital II LP | | 2020 |
| Cambridge Innovation Capital III LP | | 2025 |
| Cambridge Innovation Capital Limited | Financial services | 2012 |
| Cambridge Innovation Capital Manager Limited | Administrative & support | 2019 |
| Cambridge Innovation Consultancy Limited | Extraterritorial | 2011 |
| Cambridge Innovation Consulting Ltd. | Professional & scientific | 2011 |
| Cambridge Innovation Hub Ltd | Professional & scientific | 2015 |
| Cambridge Innovation Labs Ltd | Information & communication | 2023 |
| Cambridge Innovation System Ltd | Information & communication | 2014 |
| Cambridge Innovation Technologies Consulting Limited | Information & communication | 2014 |
| Cambridge Innovations in Ammonia Limited | Professional & scientific | 2024 |
| Cambridge Innovative Solutions (CAM2) Limited | Professional & scientific | 2012 |
| Cambridge Innovative System Solutions Limited | Professional & scientific | 2017 |
| Cambridge Innox Limited | Professional & scientific | 2022 |
| Cambridge Insights Ltd | Professional & scientific | 2015 |
| Cambridge Instrumentation Ltd. | Professional & scientific | 2015 |
| Cambridge Insulation Services Limited | Construction | 2022 |
| Cambridge Integrated Spinal Surgery Limited | Health & social care | 2023 |
| Cambridge Integrated Water Management Advisory Services Limited | Professional & scientific | 2013 |
| Cambridge Integration Ltd | Professional & scientific | 2023 |
| Cambridge Intellects Ltd | Information & communication | 2024 |
| Cambridge Intelligence Limited | Information & communication | 2011 |
| Cambridge Intelligent Life Ltd | Education | 2022 |
| Cambridge Interiors Ltd | Construction | 2019 |
| Cambridge International Academy for Advanced Studies Ltd | Information & communication | 2025 |
| Cambridge International Access Limited | Administrative & support | 2018 |
| Cambridge International Arts Festival Ltd | Arts & recreation | 2019 |
| Cambridge International Education Centre Limited | Education | 2011 |
| Cambridge International Education& Culture Centre Ltd | Education | 2013 |
| Cambridge International Events Ltd | Administrative & support | 2026 |
| Cambridge International Limited | Education | 1983 |
| Cambridge International Management College Limited | Real estate | 2005 |
| Cambridge International Parties Limited | Hospitality | 2016 |
| Cambridge International Publishing Limited | Information & communication | 2023 |
| Cambridge International Resilience Solutions Ltd | Professional & scientific | 2024 |
| Cambridge International School of English Limited | Information & communication | 2020 |
| Cambridge International Trading Ltd | Wholesale & retail | 2017 |
| Cambridge Internet Solutions Ltd | Information & communication | 2013 |
| Cambridge Inventories Ltd | Public administration | 2019 |
| Cambridge Investment Associates Limited | Professional & scientific | 1998 |
| Cambridge Investment Research Ltd | Professional & scientific | 2002 |
| Cambridge IOT Limited | Information & communication | 2016 |
| Cambridge Islamic College | Education | 2013 |
| Cambridge Jazz Festival Community Interest Company | Arts & recreation | 2014 |
| Cambridge Joining Technology Limited | Professional & scientific | 2001 |
| Cambridge Jones Ltd | Education | 2012 |
| Cambridge Kazakhstan Limited | Extraterritorial | 2015 |
| Cambridge Kebabs Ltd | Hospitality | 2018 |
| Cambridge Key Living Ltd | Hospitality | 2025 |
| Cambridge Kids Linguistics & Discovery Limited | Information & communication | 2024 |
| Cambridge Kidsclub Limited | Education | 2011 |
| Cambridge Kolkata Innovation and Therapeutic Ltd | Professional & scientific | 2018 |
| Cambridge Korean Church Ltd | Other services | 2009 |
| Cambridge Korean School | Education | 2010 |
| Cambridge KT Limited | Professional & scientific | 2010 |
| Cambridge Laboratory Technology Ltd | Information & communication | 2001 |
| Cambridge Labs Technology Limited | Information & communication | 2026 |
| Cambridge Ladies Group CIC | Health & social care | 2025 |
| Cambridge Land Consultants Surveyors Ltd | Professional & scientific | 2016 |
| Cambridge Land Economy Advisory Board | Other services | 2012 |
| Cambridge Landlord Certificates Ltd | Construction | 2025 |
| Cambridge Law Ltd | Extraterritorial | 2020 |
| Cambridge Leadership Academy C.I.C. | Education | 2012 |
| Cambridge Leadership Coaching Ltd | Professional & scientific | 2005 |
| Cambridge Leadership Development Centre Limited | Education | 2013 |
| Cambridge Learner Limited | Education | 2023 |
| Cambridge Learning Limited | Information & communication | 2003 |
| Cambridge Legacy Limited | Wholesale & retail | 2025 |
| Cambridge Legal Practice Limited | Professional & scientific | 2008 |
| Cambridge Legal Translations Ltd | Professional & scientific | 2011 |
| Cambridge Lettings Solutions Ltd | Real estate | 2026 |
| Cambridge Licensed Clearance Ltd | Other services | 2016 |
| Cambridge Lifelong Learning Limited | Education | 2013 |
| Cambridge Lighthouse Limited | Wholesale & retail | 2004 |
| Cambridge LIM Chicken Shop Ltd | Hospitality | 2026 |
| Cambridge Literary Festival Limited | Other services | 2008 |
| Cambridge Living Ltd. | Real estate | 2010 |
| Cambridge Logic Ltd | Manufacturing | 2000 |
| Cambridge Logistics Ltd | Transport & logistics | 2024 |