| C.F.G. Flying Limited | Arts & recreation | 1974 |
| C.G. Interior Solutions Limited | Construction | 2013 |
| C.L.Eaglen & Company Limited | Extraterritorial | 1958 |
| C.P. Martin Reinforcements Ltd | Construction | 2018 |
| C.P.I Estate Agents Ltd | Real estate | 2015 |
| C.R.S Marine Carpentry Ltd | Manufacturing | 2024 |
| C.S.C Solutions Limited | Construction | 2014 |
| C.U. Aircraft & Maintenance Ltd | Manufacturing | 2025 |
| C3 IP Ltd. | Professional & scientific | 2005 |
| C3 Language Holdings Ltd | Financial services | 2026 |
| CA Inspections Ltd | Manufacturing | 2025 |
| CA Jennings Limited | Professional & scientific | 2017 |
| Cabbells Limited | Information & communication | 2016 |
| Cabwise Limited | Transport & logistics | 2024 |
| Cacao Beach Ltd | Hospitality | 2019 |
| Cactus Recruitment Limited | Extraterritorial | 2021 |
| CAD & Revit Design Service Ltd | Professional & scientific | 2018 |
| Cadap Ltd | Real estate | 2023 |
| Cadcentre Limited | Extraterritorial | 2001 |
| Cadcentre Pension Trustee Limited | Professional & scientific | 1990 |
| Cadcentre Property Limited | Real estate | 1986 |
| Cade Hill Investments Limited | Information & communication | 2016 |
| Cade Hill Limited | Financial services | 2021 |
| Cadfem UK Ltd | Information & communication | 1996 |
| Cadgi Limited | Information & communication | 2023 |
| Cadi Limited | Wholesale & retail | 2024 |
| Cadmar Ltd | Professional & scientific | 2019 |
| Cadsoft Solutions Limited | Wholesale & retail | 2003 |
| Caec Howard Limited | Real estate | 2024 |
| Caelora Beauty Limited | Wholesale & retail | 2026 |
| Caernafon House Residents Association Limited | Households | 2007 |
| Cafe Arena CB 1 Ltd | Hospitality | 2025 |
| Cafe Arena CB2 Ltd | Other services | 2015 |
| Cafe Milton CB Ltd | Hospitality | 2025 |
| CAFE2U Cambridge South Ltd | Hospitality | 2025 |
| Cafetrumpington Ltd | Hospitality | 2025 |
| Cafsa Ltd | Other services | 2023 |
| Café Côté Bois Ltd | Hospitality | 2024 |
| Café D'Or Ltd | Hospitality | 2025 |
| Cage & Park Limited | Real estate | 2022 |
| Cagi Ltd | Construction | 2025 |
| Cahp Ltd | Construction | 2024 |
| Caine R & D Consulting Ltd | Health & social care | 2006 |
| Cainers Limited | Mining & quarrying | 2023 |
| Cairncross Professional Services (CPS) Ltd | Information & communication | 2024 |
| Cairnstone Technologies Ltd | Information & communication | 2025 |
| Caius Conferences Ltd | Administrative & support | 2019 |
| Caius Property Services Limited | Wholesale & retail | 1993 |
| Caiv LP | | 2018 |
| Caivp LLP | | 2024 |
| Cakes by Gabriella Ltd | Manufacturing | 2025 |
| Cakes by Lexi Ltd | Manufacturing | 2022 |
| Calabrianpizza Ltd | Hospitality | 2024 |
| Calanna Consulting Limited | Information & communication | 2025 |
| CALC30 Ltd | Professional & scientific | 2025 |
| Calibre Property Services Group Ltd | Water & waste | 2025 |
| Calico & Goose Ventures Limited | Professional & scientific | 2023 |
| Californium Mining Ltd | Manufacturing | 2022 |
| Caligo Technologies Ltd | Professional & scientific | 2023 |
| Calixte Field OPS Ltd | Manufacturing | 2026 |
| Call Streams Solution Ltd | Administrative & support | 2025 |
| Calm Driving Academy Limited | Education | 2023 |
| Calm Resurgence Limited | Other services | 2023 |
| Calmcore Ltd | Other services | 2025 |
| Calne Vehicle Management Limited | Wholesale & retail | 2003 |
| Calon Property Ltd | Real estate | 2025 |
| Caloo.Life Ltd | Administrative & support | 2020 |
| Caltec Instrument Services Limited | Manufacturing | 2009 |
| Calvary Chapel Cambridge Limited | Other services | 2011 |
| Calverley's Brewery Ltd | Manufacturing | 2013 |
| Calvert Consulting Limited | Professional & scientific | 2018 |
| Calvin Metrics Limited | Professional & scientific | 2025 |
| Calymene Holdings Limited | Financial services | 2016 |
| Calypso Investment Limited | Financial services | 2024 |
| CAM Boathouse Company Limited(The) | Arts & recreation | 1959 |
| CAM Buoys Ltd | Wholesale & retail | 2022 |
| CAM CAB Properties Ltd | Real estate | 2012 |
| CAM Cabin Stays Ltd | Real estate | 2026 |
| CAM Chalk Ltd | Mining & quarrying | 2020 |
| CAM Eduhub Ltd | Education | 2025 |
| CAM Facades Ltd | Construction | 2015 |
| CAM FEN Ltd | Information & communication | 2024 |
| CAM Garage Ltd | Wholesale & retail | 2013 |
| CAM Gas&Heating Ltd | Construction | 2020 |
| CAM House Letting and Developments Ltd | Real estate | 2014 |
| CAM Innovations Ltd | Professional & scientific | 2019 |
| CAM Integrity Ltd | Professional & scientific | 2025 |
| CAM Kitchens Limited | Wholesale & retail | 2025 |
| CAM Osteopathy Ltd | Health & social care | 2016 |
| CAM Park Arena Limited | Agriculture & fishing | 2022 |
| CAM Park Limited | Agriculture & fishing | 2022 |
| CAM Pathology Consultancy Ltd | Health & social care | 2019 |
| CAM Physio UK Ltd | Health & social care | 2016 |
| CAM Planning Ltd | Professional & scientific | 2016 |
| CAM Quench Ltd | Wholesale & retail | 2025 |
| CAM Rivers Granta Club Ltd | Administrative & support | 2022 |
| CAM Rivers Trading Ltd | Wholesale & retail | 2024 |
| CAM Sourcing Ltd | Wholesale & retail | 2022 |
| CAM South Indian Ltd | Hospitality | 2025 |
| CAM Sports Performance Ltd | Arts & recreation | 2023 |