| Saunders Family Limited | Financial services | 2022 |
| Saunders Holding Project 1 Limited | Construction | 2022 |
| Sayers Property Development Limited | Real estate | 2018 |
| SB Mentoring Ltd | Education | 2022 |
| Scarecon Ltd | Arts & recreation | 2020 |
| SCD Property Investments Ltd | Real estate | 2020 |
| SCD Property Solutions Ltd | Information & communication | 2020 |
| Schmico Ltd | Real estate | 2021 |
| School Scan Limited | Information & communication | 2025 |
| Schwyz Ltd | Professional & scientific | 2026 |
| Seemz Beauty Ltd | Other services | 2025 |
| Self Build Materials Ltd | Wholesale & retail | 2019 |
| Self Store Ltd | Transport & logistics | 2024 |
| Sensory Hugs Limited | Wholesale & retail | 2024 |
| Sensual YOU Ltd | Wholesale & retail | 2018 |
| SET Stone Tiling Ltd | Construction | 2026 |
| SF Health Limited | Health & social care | 2017 |
| SG Connections Ltd | Wholesale & retail | 2022 |
| Shade Sail Blinds Limited | Construction | 2017 |
| Shade Sculpture Ltd | Construction | 2022 |
| Shadeseekers Ltd | Construction | 2023 |
| Shahadah Ltd | Wholesale & retail | 2012 |
| Sharia Tax Advice Ltd | Professional & scientific | 2018 |
| Sharpe Sighting Limited | Administrative & support | 2013 |
| Shave Cross Limited | Construction | 2011 |
| Shelby Property Investments Ltd | Real estate | 2024 |
| Sherston Investments Ltd | Real estate | 2016 |
| Shipment Solutions Ltd | Transport & logistics | 2022 |
| Shorebird Homes Ltd | Real estate | 2025 |
| Shreemtec Limited | Professional & scientific | 2014 |
| Shutter Magic Ltd | Wholesale & retail | 2022 |
| Siaram Limited | Administrative & support | 2019 |
| Sign of the Times Limited | Professional & scientific | 2003 |
| Silkyh Hickman Ltd | Other services | 2026 |
| Silver Premier Store Limited | Wholesale & retail | 2026 |
| Silvermoon Investments Ltd | Real estate | 2021 |
| Silvermoon Property Solutions Ltd | Real estate | 2021 |
| Simpkins & Simpkins Limited | Manufacturing | 2013 |
| Simpkins Sealants Ltd | Construction | 2026 |
| SJ Electrical Contracting Ltd | Construction | 2021 |
| SJB Accounting Services Limited | Professional & scientific | 2023 |
| SK Cooling Ltd | Construction | 2025 |
| SK Residential Holdings Limited | Real estate | 2026 |
| SK Technology Holdings Limited | Financial services | 2025 |
| Skoots Moving Systems Limited | Manufacturing | 1977 |
| Skyrock Property Investment Ltd | Real estate | 2020 |
| Slate Blue Investments Ltd | Real estate | 2021 |
| Slowly by Consensus Ltd | Wholesale & retail | 2019 |
| Smart Integrated Ltd | Real estate | 2014 |
| Smart Integrated Security Ltd | Administrative & support | 2015 |
| Smart Integrated Solutions Ltd | Administrative & support | 2013 |
| Smart Mushrooms Ltd | Agriculture & fishing | 2022 |
| Smart Repairers Limited | Wholesale & retail | 2002 |
| Smartchart Limited | Education | 2014 |
| Smooth Websites Ltd | Information & communication | 2021 |
| Snellington Enterprises Ltd | Financial services | 2022 |
| SO Green Ltd | Professional & scientific | 2020 |
| Social BEE Media Ltd | Professional & scientific | 2021 |
| Solarcrowd Limited | Professional & scientific | 2022 |
| Solid Angling Solutions Ltd | Wholesale & retail | 2025 |
| Somerford Mini Limited | Wholesale & retail | 2002 |
| Sonnschein Ltd | Health & social care | 2008 |
| Sooty Brushes Ltd | Administrative & support | 2016 |
| Sophie Bean Properties Ltd | Real estate | 2020 |
| Sophie the Coach Limited | Professional & scientific | 2014 |
| Sophies Beauty Spot Ltd | Other services | 2015 |
| Southwest Joint and Spine Centre Ltd | Health & social care | 2026 |
| Southwest Precast Ltd | Construction | 2010 |
| Space for Living Ltd | Real estate | 2018 |
| Spacewell Ltd | Real estate | 2019 |
| Sparklingfoods CIC | Hospitality | 2025 |
| Spartan Luxury Homes Ltd | Construction | 2020 |
| Springfield Heights Management Company Limited | Real estate | 1987 |
| Spudmachine Studios Limited | Information & communication | 2019 |
| SQ Plumbing and Heating Ltd | Construction | 2024 |
| Sqep Ltd | Professional & scientific | 2014 |
| SRD Driver Solutions Ltd | Transport & logistics | 2025 |
| ST Mary's Courtyard Management Company Limited | Households | 1992 |
| ST Mary's School (Calne) Services Limited | Arts & recreation | 2000 |
| Stable Holiday Lets Ltd | Hospitality | 2024 |
| Star Quality Properties Ltd | Real estate | 2021 |
| Starfish & Coffee LLP | | 2005 |
| Stayseekers Ltd | Administrative & support | 2021 |
| Step UP Supplements Ltd | Wholesale & retail | 2022 |
| Sterling Brown Property Company Ltd | Real estate | 2021 |
| Sterling Brown Property Group Ltd | Real estate | 2021 |
| Steve Barnes Limited | Wholesale & retail | 2024 |
| Stirling Focus Holdings Ltd | Real estate | 2022 |
| Stockley Property Solutions Ltd | Real estate | 2021 |
| Stockwell Agriculture Ltd | Administrative & support | 2023 |
| Stoggle Properties Ltd | Real estate | 2023 |
| Stoggle Stays Ltd | Administrative & support | 2023 |
| Stone Trail Investments Ltd | Real estate | 2023 |
| Stoneridge Traders Limited | Wholesale & retail | 2003 |
| Stones Removals and Storage Limited | Transport & logistics | 2014 |
| Stoneways Fireplaces and Stoves Limited | Construction | 2011 |
| Strand Property Investments Ltd | Real estate | 2021 |
| Street to School Limited | Arts & recreation | 2020 |
| Stress-Free Property Solutions Ltd | Real estate | 2022 |
| Stretchsuit Global Ltd | Wholesale & retail | 2024 |