| Diamond Nails & Spa 50 Ltd | Other services | 2025 |
| Diamond Rental (Management) Limited | Real estate | 2006 |
| Digital Consultancy Ltd | Information & communication | 2016 |
| Digital Draughting Services Ltd | Construction | 2024 |
| Digital Rebel Academy Limited | Education | 2022 |
| Digital Thrive Ltd | Professional & scientific | 2018 |
| Dino Grass Ltd | Administrative & support | 2022 |
| Direct 2U Training & Consultancy Limited | Education | 2014 |
| Direct Funeral Services Limited | Other services | 2023 |
| Direct Healthcare Group Holdings Limited | Extraterritorial | 2016 |
| Direct Healthcare Group Limited | Manufacturing | 2004 |
| Direct Healthcare Group Management Limited | Extraterritorial | 2016 |
| Direct Healthcare Services Limited | Extraterritorial | 2017 |
| Direct Passenger Transport Limited | Administrative & support | 2019 |
| Dirty Duck Group Limited | Hospitality | 2017 |
| Disability Claims & Appeals Ltd | Professional & scientific | 2024 |
| Disability Claims UK Limited | Professional & scientific | 2022 |
| DJ Bodywork Solutions Ltd | Wholesale & retail | 2021 |
| DJB Professional Solutions Ltd | Manufacturing | 2024 |
| DJS Property Developments Ltd | Real estate | 2024 |
| DM Discretion Ltd | Administrative & support | 2026 |
| DMR Render Specialists Ltd | Construction | 2023 |
| DNA Heating Limited | Construction | 2003 |
| Dolgarreg Ltd | Professional & scientific | 2024 |
| Dolmush Taxi Share Ltd | Transport & logistics | 2024 |
| DOM O'Brien Fire and Security Ltd | Administrative & support | 2018 |
| Dominic Jones Heating Ltd | Construction | 2020 |
| DON Elsbury (Plant Sales) Limited | Construction | 1975 |
| Door Two Door Windows Limited | Construction | 2023 |
| Doughnutters Limited | Wholesale & retail | 2021 |
| DR AJM Ltd | Health & social care | 2023 |
| DR B Creative CIC | Arts & recreation | 2024 |
| DR Brain Stats Ltd | Information & communication | 2018 |
| Dragon Fleetcare Limited | Manufacturing | 2006 |
| Dragon FS Limited | Professional & scientific | 2025 |
| Dragon Play & Sports Ltd | Education | 2018 |
| Dragon Press Ltd | Information & communication | 2021 |
| Dragonlens Ltd | Information & communication | 2024 |
| Drain Repair UK Ltd | Water & waste | 2020 |
| Dream Team Soccer School Limited | Arts & recreation | 2005 |
| Drew FM Limited | Professional & scientific | 2025 |
| Drone Evolution Limited | Professional & scientific | 2018 |
| Drsmk Ltd | Real estate | 2020 |
| Drtjb Limited | Health & social care | 2021 |
| Dubs Draws Limited | Wholesale & retail | 2024 |
| Duck Dingle Dell Ltd | Professional & scientific | 2024 |
| Dugann's DEN Ltd | Hospitality | 2024 |
| Duvan Management Limited | Real estate | 1997 |
| DW Psychology Service Ltd | Education | 2022 |
| DW Studio Holdings Limited | Financial services | 2024 |
| DW Studio Ltd | Information & communication | 2013 |
| Dynamic Capability Engineering Ltd | Professional & scientific | 2014 |
| Dynamic Rail Civils Ltd | Construction | 2023 |
| E & M Construction Services Limited | Construction | 2007 |
| E & M Fencing Contractors Limited | Construction | 1997 |
| E C Mot's and Service Centre Limited | Wholesale & retail | 2007 |
| E&P Trading Ltd | Wholesale & retail | 2024 |
| E-Smart Spraytech International Ltd | Construction | 2024 |
| E.G M&J Contracts Limited | Wholesale & retail | 2021 |
| EAA Projects Ltd | Construction | 2011 |
| Eaku Ltd | Other services | 2015 |
| Earthwise Geology Ltd | Professional & scientific | 2024 |
| EAST’98 Ltd | Professional & scientific | 2020 |
| Easy Access Showers Limited | Manufacturing | 2007 |
| Easy Store Solutions Limited | Transport & logistics | 2020 |
| Easyware Ltd | Wholesale & retail | 2018 |
| Eatfresh Wales Limited | Extraterritorial | 2002 |
| EBX Ltd | Manufacturing | 2025 |
| Echo Drainage Ltd | Water & waste | 2016 |
| Eco-Hygiene Limited | Extraterritorial | 2003 |
| Eco-Recover Ltd | Water & waste | 2021 |
| Ecobrix ICF Ltd | Manufacturing | 2024 |
| Ecoheat Energy Limited | Professional & scientific | 2025 |
| EDD Response Maintenance Services Ltd | Manufacturing | 2021 |
| Edinho Ltd | Health & social care | 2021 |
| EDPSYCH4CHANGE Ltd | Education | 2024 |
| Educalis Community Interest Company | Administrative & support | 2015 |
| Edwards and Sons Developments Ltd | Real estate | 2024 |
| EHS Bar Company Limited | Hospitality | 2025 |
| EJ Care Solution Limited | Health & social care | 2019 |
| Electrical & GAS Care Limited | Manufacturing | 2016 |
| Electrical Industry Training Academy Limited | Construction | 2021 |
| Electrical TEC Ltd | Manufacturing | 2014 |
| Elegance Aesthetics Ltd | Other services | 2024 |
| Element GAS Ltd | Construction | 2013 |
| Elevate Web Ltd | Wholesale & retail | 2011 |
| Elfie Contracting Ltd | Professional & scientific | 2018 |
| ELI Electrical Ltd | Extraterritorial | 2023 |
| ELI Rose Developments Ltd | Construction | 2022 |
| Elit Barber Ltd | Other services | 2017 |
| Elite Construction Projects Ltd | Construction | 2024 |
| Ella Bioenergy Ltd | Energy | 2024 |
| Ellis Cunningham Consulting Ltd | Professional & scientific | 2021 |
| Elsby Enterprises Ltd | Administrative & support | 2013 |
| EMM Surveyors Limited | Professional & scientific | 2008 |
| Emmalily Ltd | Information & communication | 2008 |
| Empire Floor Trade Supplies Limited | Wholesale & retail | 2024 |
| Empower the People Limited | Administrative & support | 2023 |
| Empower the People Trustees Limited | Extraterritorial | 2023 |
| Emtrek Contracting Ltd | Construction | 2021 |