| Rentacrate Limited | Professional & scientific | 2003 |
| Repair TEK Ltd | Other services | 2019 |
| Residential Sprinkler Protection Limited | Construction | 2013 |
| Resivent Ltd | Construction | 2022 |
| Response Property Repairs Limited | Administrative & support | 2013 |
| Revive Property Maintenance and Repair Limited | Other services | 2022 |
| Rhiara Consulting Ltd | Financial services | 2026 |
| Rhino Electrical Inspection and Testing Ltd | Construction | 2021 |
| RHJ Support Services Limited | Administrative & support | 2020 |
| RHS Trading Limited | Hospitality | 2026 |
| Rhymark Electrical Services Ltd | Construction | 2021 |
| Richards CNC Engineering Ltd | Manufacturing | 2023 |
| Richwest Engineering Limited | Manufacturing | 2007 |
| Ridgeway Golf 4 ALL Ltd | Arts & recreation | 2013 |
| Rily Accountancy and Business Solutions Limited | Professional & scientific | 2007 |
| Rily Ltd | Professional & scientific | 2007 |
| Rily Publications Limited | Information & communication | 2001 |
| Rily Sales Limited | Administrative & support | 2007 |
| Risen Holdings Limited | Financial services | 2025 |
| Risksured Ltd. | Information & communication | 2019 |
| RJ Ellacott (ISW) Ltd | Health & social care | 2023 |
| RL Digital Marketing Limited | Professional & scientific | 2025 |
| RLL Building Services Limited | Construction | 2019 |
| Road Safety Associates Limited | Professional & scientific | 2026 |
| ROB French Limited | Transport & logistics | 2015 |
| Robert Kinsella Limited | Information & communication | 2019 |
| Rock & Roll Ltd | Wholesale & retail | 2025 |
| Rockprintco Ltd | Manufacturing | 2024 |
| Rockwood Equestrian Limited | Agriculture & fishing | 2022 |
| ROD Woodward Ltd | Arts & recreation | 2004 |
| Roger Crookes Services Limited | Administrative & support | 2017 |
| Rogers Estate Coffees (UK) Ltd | Manufacturing | 2006 |
| RON Coates & Co Limited | Financial services | 2001 |
| Rosaria PDI Limited | Real estate | 2018 |
| Rosewood Properties (Caerphilly) Limited | Real estate | 2003 |
| Rothwell Fabrication Ltd | Manufacturing | 2025 |
| Rowland Ward Services Limited | Construction | 2025 |
| Rowlands Property Services Ltd | Households | 2025 |
| Roy's Quality Foods Limited | Extraterritorial | 1998 |
| RP Palace Limited | Hospitality | 2022 |
| RRS Facilities and Building Group Ltd | Construction | 2025 |
| RS Staffing Group Ltd | Administrative & support | 2020 |
| RTR Consultancy Services Limited | Construction | 2021 |
| Ruanne Creations Ltd | Extraterritorial | 2024 |
| Rucha & Nikhil Properties Limited | Real estate | 2022 |
| Ruck Group Ltd | Manufacturing | 2017 |
| Ruon Properties Limited | Real estate | 2001 |
| Ruperra Conservation Trust | Agriculture & fishing | 1996 |
| Rutland Road Motor Company Limited | Wholesale & retail | 2024 |
| RWC Quality Carpentry Ltd Limited | Construction | 2025 |
| RXI International Logistics Limited | Transport & logistics | 2021 |
| RXI Logistics Ltd | Transport & logistics | 2019 |
| Ryzy Trading CYF | Wholesale & retail | 2025 |
| S M Adams Holdings Ltd | Financial services | 2026 |
| S&J Fitness Ltd | Arts & recreation | 2025 |
| S-Dog Limited | Education | 2023 |
| S. W. S. Formwork Limited | Construction | 2018 |
| S.I.B. Air Conditioning & Mechanical Services Limited | Energy | 2004 |
| SA Asset Management Ltd | Real estate | 2022 |
| SA Property Completion Ltd | Real estate | 2022 |
| Sabre Computer Services Limited | Information & communication | 2000 |
| Sacred Bloom Ltd | Health & social care | 2026 |
| Safety Industry Training Academy Limited | Education | 2021 |
| Safety-Counts Occupational Services Limited | Education | 2021 |
| Salon Angels Beauty & Aesthetics Limited | Other services | 2020 |
| Salon Ombre Limited | Other services | 2017 |
| Saltown Limited | Real estate | 1980 |
| Samantha Greer ISW Ltd | Health & social care | 2023 |
| Sarah Tamsin Digital Limited | Information & communication | 2020 |
| Sauce Interiors Limited | Construction | 2024 |
| Sauce Property Ltd | Real estate | 2026 |
| Savepoint Gaming CIC | Wholesale & retail | 2019 |
| SBP Music Limited | Arts & recreation | 2020 |
| SBR Clothing Cyfyngedig | Wholesale & retail | 2020 |
| SBR Designs Limited | Professional & scientific | 2016 |
| Scents by Stabz Ltd | Manufacturing | 2025 |
| Scriven Services Ltd | Administrative & support | 2026 |
| SE Local Power Solutions Ltd | Energy | 2022 |
| Sean Gregory Nicholas Limited | Extraterritorial | 2022 |
| Sean Nicholas Limited | Extraterritorial | 2022 |
| Seasons Florists (Treforest) Limited | Wholesale & retail | 2020 |
| Security Industry Training Academy Limited | Administrative & support | 2021 |
| Security Risk Management Limited | Administrative & support | 2000 |
| Senevo Designs Ltd | Construction | 2021 |
| Senghani Father & SON Ltd | Wholesale & retail | 2018 |
| Senghenydd RFC Limited | Arts & recreation | 2012 |
| September Homecare Limited | Health & social care | 2019 |
| Seren DWT CIC | Health & social care | 2022 |
| Seren Electrical Supplies (Holdings) Ltd | Financial services | 2017 |
| Seren Electrical Supplies Limited | Wholesale & retail | 2010 |
| Servicetracker Ltd | Information & communication | 2013 |
| Servini Financial Planning Limited | Financial services | 2018 |
| SEV Consulting Limited | Information & communication | 2015 |
| SGA World Limited | Professional & scientific | 2019 |
| SH Curry Ltd | Hospitality | 2024 |
| SH Legal Searches Ltd | Administrative & support | 2011 |
| Shade Cosmetics Ltd | Wholesale & retail | 2023 |
| Shallish Stocktakers Limited | Other services | 2019 |
| Shaplands Property Sales Ltd | Real estate | 2023 |
| Sharon Shakeela Rashid Ltd | Extraterritorial | 2022 |