| Tyre Depot Ltd | Wholesale & retail | 2024 |
| Tyre Station Bury Ltd | Wholesale & retail | 2023 |
| Tyre Station Ltd | Wholesale & retail | 2023 |
| Tyres Assist Limited | Wholesale & retail | 2013 |
| Tyrol Limited | Financial services | 2025 |
| U.T.Company Limited | Real estate | 1955 |
| UAP Group Limited | Professional & scientific | 2018 |
| UAP Holdings Limited | Professional & scientific | 2018 |
| UAP Services Limited | Professional & scientific | 2018 |
| Ubservicesuk Limited | Other services | 2015 |
| Ubuntu Living Limited | Construction | 2020 |
| UCC United Consulting Company Ltd | Information & communication | 2014 |
| UCL Comms Ltd | Construction | 2023 |
| UDM Bargains Ltd | Wholesale & retail | 2025 |
| UDM Pound Saver Ltd | Wholesale & retail | 2025 |
| UDM Pound Saver PVT Ltd | Wholesale & retail | 2022 |
| UFS United FM Limited | Administrative & support | 2026 |
| Ugarv Ltd | Transport & logistics | 2021 |
| UIE Group Limited | Real estate | 2025 |
| UK Business Switch Limited | Administrative & support | 2020 |
| UK Centre for Sustainable Learning (Ukcsl) Limited | Information & communication | 2025 |
| UK Defence Services Ltd | Information & communication | 2024 |
| UK Digital Limited | Wholesale & retail | 1999 |
| UK Energy Limited | Other services | 2016 |
| UK Mega Shop Ltd | Wholesale & retail | 2024 |
| UK Modz Limited | Wholesale & retail | 2024 |
| UK Online Training Ltd | Professional & scientific | 2015 |
| UK Prestige Windows & Doors Limited | Construction | 2025 |
| UK Timber Structures Ltd | Administrative & support | 2013 |
| UK United Logistic Limited | Transport & logistics | 2025 |
| UK White Horse Limited | Wholesale & retail | 2018 |
| Uk-Eats Ltd | Information & communication | 2021 |
| Ukacab Ltd | Education | 2025 |
| Ukcompany Ltd | Information & communication | 2012 |
| UKE Group North CIC | Education | 2023 |
| Ukgwr NW Limited | Construction | 2026 |
| UKMEDS4U.COM Limited | Wholesale & retail | 2016 |
| Ukmla Limited | Education | 2022 |
| Ukort Limited | Wholesale & retail | 2025 |
| Ultima Thule Technology Limited | Information & communication | 1999 |
| Ultimate Outdoors Limited | Professional & scientific | 1912 |
| Ultimate Productions Limited | Hospitality | 2020 |
| Ultios Chemicals Ltd | Wholesale & retail | 2025 |
| Ultrabarbers Limited | Other services | 2025 |
| Ultrabrands Ltd | Wholesale & retail | 2020 |
| Ultrasound Solutions Ltd | Health & social care | 2019 |
| Uncle Flafel Ltd | Hospitality | 2025 |
| Under One Roof Construction Ltd | Real estate | 2026 |
| Under Pressure Cleaning, Valeting & Maintenance Ltd | Other services | 2026 |
| Under Pressure Power Washing Ltd | Construction | 2026 |
| Uneak-N-Teak Limited | Wholesale & retail | 2024 |
| UNI Route UK Ltd | Education | 2023 |
| Unibrak Limited | Administrative & support | 2007 |
| Unified Horizon Ltd | Transport & logistics | 2023 |
| Unifiller (UK) Ltd | Extraterritorial | 1997 |
| Unifyops Ltd | Information & communication | 2026 |
| Unikum Gastro&Playhall Service Ltd | Information & communication | 2014 |
| Uniqe Media Limited Partnership | | 2008 |
| Unique Shutters and Shopfronts Ltd | Manufacturing | 2023 |
| United Investments (UK) Limited | Professional & scientific | 2000 |
| United Klima Technologies Engineering Ltd | Professional & scientific | 2014 |
| Unity Catering Ltd | Administrative & support | 2017 |
| Unity House (Wigan) Limited | Real estate | 2015 |
| Unity News Network Ltd | Information & communication | 2018 |
| Unlimited Care Plus Ltd | Health & social care | 2023 |
| Unlock Central Ltd | Information & communication | 2026 |
| Untitled Artwork Ltd | Arts & recreation | 2022 |
| Upgrade Results Limited | Education | 2025 |
| Uplend Ltd | Financial services | 2025 |
| Uplift Unite C.I.C. | Education | 2021 |
| Uplifting Women Ltd | Wholesale & retail | 2021 |
| Upsidedownbar Ltd | Hospitality | 2023 |
| Upvc Renew Limited | Construction | 2019 |
| Urban Decor (Bury) Ltd | Construction | 2019 |
| Urban Stone Contracts Limited | Construction | 2009 |
| Urgent Care Liverpool Ltd | Health & social care | 2026 |
| US Estates Limited | Real estate | 2021 |
| US Homes Ltd | Real estate | 2022 |
| USC Bury Ltd | Health & social care | 2010 |
| Usc-Universal Service Company Ltd | Information & communication | 2006 |
| Ustad Traders Limited | Wholesale & retail | 2024 |
| Utility Network Connections Limited | Professional & scientific | 2011 |
| UV International Ltd | Wholesale & retail | 2015 |
| Uzair Travel Ltd | Transport & logistics | 2025 |
| V&D Investments Ltd | Real estate | 2022 |
| V&L Scaffolding Ltd | Construction | 2013 |
| V.Media Ltd | Information & communication | 2019 |
| V.S.F. Ltd | Construction | 2009 |
| V2L Limited | Administrative & support | 2008 |
| V2M25 Limited | Information & communication | 2022 |
| Vacayco Ltd | Hospitality | 2023 |
| Vacore Ltd | Wholesale & retail | 2025 |
| Vadco Limited | Extraterritorial | 2024 |
| Vail Moose Ltd | Real estate | 2021 |
| Vajo African and Caribbean Super Store Limited | Wholesale & retail | 2025 |
| Vajra Tech Ltd | Information & communication | 2026 |
| Valands Ltd | Other services | 2018 |
| Valdoc Storage Ltd | Administrative & support | 2025 |
| Vale Forty SIX Limited | Arts & recreation | 2023 |
| Valebond Limited | Extraterritorial | 2020 |