| Emotiv Events Limited | Wholesale & retail | 2013 |
| Empathy Holistic Buddies CIC | Health & social care | 2022 |
| Empire Facilities Limited | Transport & logistics | 2016 |
| Empire Occasions Ltd | Administrative & support | 2024 |
| Empirical Design Ltd | Professional & scientific | 2026 |
| Empirical Investments Ltd | Financial services | 2026 |
| Employment Solutions (Holdings) Limited | Financial services | 2014 |
| Employment Solutions Limited | Administrative & support | 1998 |
| Emporio X Ltd | Wholesale & retail | 2023 |
| Empowering Young Women | Education | 2022 |
| Emptra Ltd | Administrative & support | 2023 |
| Enabled Living Group Limited | Administrative & support | 2024 |
| Energinie Ltd | Wholesale & retail | 2016 |
| Energy Advice Bureau Limited | Wholesale & retail | 2023 |
| Energy Communications (UK) Limited | Information & communication | 2024 |
| Energy Counsel Limited | Professional & scientific | 2021 |
| Energy Insulation Grants Ltd | Wholesale & retail | 2024 |
| Energy Masters UK Limited | Energy | 2024 |
| Energy Media UK Limited | Information & communication | 2017 |
| Energy Plus Power Contracting Limited | Construction | 2022 |
| Energysmart Nationwide Limited | Construction | 2017 |
| Engine Express Limited | Wholesale & retail | 2019 |
| Engraved Limited | Administrative & support | 2008 |
| Enhance by Ariahbelle Ltd | Other services | 2025 |
| Enhanced by Kiah Limited | Wholesale & retail | 2023 |
| Enheart Ltd | Real estate | 2025 |
| Enprise Network Ltd | Professional & scientific | 2022 |
| Entrance Matsdirect Ltd | Manufacturing | 2013 |
| Entrepreneurial Itch Scratchers Ltd | Wholesale & retail | 1975 |
| Envirogreen Properties Limited | Construction | 2022 |
| Envirokem Limited | Wholesale & retail | 2017 |
| Envypalms Limited | Manufacturing | 2022 |
| EPA Pro Prep Ltd | Education | 2025 |
| EPF Ltd | Construction | 2025 |
| Ephg Limited | Construction | 2015 |
| Epic Gifts Limited | Wholesale & retail | 2024 |
| Epic Goods Ltd | Wholesale & retail | 2025 |
| Epidamn Properties Ltd | Real estate | 2024 |
| Epresto Limited | Information & communication | 2011 |
| Epsom Incentives Ltd | Administrative & support | 1996 |
| Epsom Veterans Support Limited | Administrative & support | 2024 |
| Epstein FIC Limited | Professional & scientific | 2018 |
| Epstein FIC Property 2 Limited | Real estate | 2018 |
| EQA Holdings Ltd | Professional & scientific | 2025 |
| Equilibrium Architects Limited | Professional & scientific | 2005 |
| Equilibrium Property Investments Ltd | Real estate | 2018 |
| Equilibrium Property Solutions Ltd | Real estate | 2021 |
| Equinox Insights Limited | Professional & scientific | 2025 |
| Equitrack Ltd | Information & communication | 2025 |
| Ergocurative Limited | Wholesale & retail | 2015 |
| Ergomonkey Limited | Administrative & support | 2001 |
| Ergospaces Limited | Wholesale & retail | 2015 |
| Eridon Ltd | Hospitality | 2003 |
| ERM Contracts Limited | Extraterritorial | 2015 |
| ERS Vending Ltd | Wholesale & retail | 2025 |
| ES Group Holdings Limited | Financial services | 2026 |
| ES Group Properties Ltd. | Real estate | 2009 |
| ES Steel Holdings Limited | Construction | 2019 |
| ES Steel Limited | Construction | 2006 |
| Esave Accountancy Limited | Professional & scientific | 2010 |
| Esbe Ltd | Wholesale & retail | 2024 |
| Eseni Ltd | Wholesale & retail | 2024 |
| ESI Tech Ltd | Information & communication | 2015 |
| Eslanium Ltd | Information & communication | 2025 |
| ESP Arenas Limited | Arts & recreation | 2025 |
| Esports News International Limited | Information & communication | 2020 |
| Esprescott Holdings Ltd | Real estate | 2026 |
| Essa Sameday Logistics Ltd | Transport & logistics | 2025 |
| Essanbee Jewellers Limited | Wholesale & retail | 2015 |
| Esselle (Properties) Limited | Real estate | 1998 |
| Esselle Estates Limited | Construction | 2011 |
| Esselle Homes Limited | Construction | 1998 |
| Essential Aromas Ltd | Health & social care | 2008 |
| Essential Bulk Goods Ltd | Wholesale & retail | 2023 |
| Essential Contract Cleaning Limited | Administrative & support | 2013 |
| Essential Education Limited | Administrative & support | 2003 |
| Essential Financial Services Limited | Professional & scientific | 2011 |
| Essential Hygiene Limited | Administrative & support | 2005 |
| Estuk Property Solutions Ltd | Construction | 2024 |
| Esync Sales Limited | Wholesale & retail | 2025 |
| Eternal Vets (Subsidiaries) Ltd | Professional & scientific | 2024 |
| Eternal Vets Limited | Professional & scientific | 2018 |
| Eternally Curious Limited | Wholesale & retail | 2026 |
| ETF Group Limited | Financial services | 2025 |
| Ethical Carbon Offsetting Limited | Professional & scientific | 2021 |
| EUR Ltd | Wholesale & retail | 2020 |
| Eurla Ltd | Hospitality | 2025 |
| Euro Service & Consulting Ltd | Real estate | 2017 |
| Euro Trade & Service Company | Other services | 2017 |
| Europ Service &Consulting Ltd | Financial services | 2015 |
| European Holding Ltd | Professional & scientific | 2014 |
| European Help Foundation | Real estate | 2022 |
| European Versicherungsoffice Ltd | Financial services | 2017 |
| Europewide Marketing Limited | Information & communication | 2016 |
| Europrint 2000 Ltd | Manufacturing | 2016 |
| Eurpean Developers Ltd | Construction | 2024 |
| EV Chargers North West Ltd | Construction | 2022 |
| Eva's Cleaning & Maintenance Services Ltd | Administrative & support | 2013 |
| Evadare Ltd | Arts & recreation | 2024 |
| Evan MAD Ltd | Information & communication | 2016 |