| EOS Enviro Ltd | Wholesale & retail | 2009 |
| EPC Scout Ltd | Information & communication | 2026 |
| Epic Chess Ltd | Wholesale & retail | 2022 |
| Epic Group London Ltd | Construction | 2026 |
| Epic Vibe Ltd | Arts & recreation | 2022 |
| Epical Global Ltd | Health & social care | 2019 |
| Epilex Limited | Wholesale & retail | 2024 |
| Epiphany Language Studio Limited | Other services | 2019 |
| Epsan Ltd | Construction | 2024 |
| Epsilon Generation Limited | Construction | 2017 |
| EQH Limited | Hospitality | 2004 |
| Equanimity Elite Limited | Professional & scientific | 2025 |
| Equator International Limited | Wholesale & retail | 2024 |
| Equestrian Circles Ltd | Wholesale & retail | 2025 |
| Equiliberta Ltd | Agriculture & fishing | 2023 |
| Equilibrio Ltd | Hospitality | 2025 |
| Equine Healthcare Qualifications Limited | Other services | 2017 |
| Equipify Ltd | Wholesale & retail | 2025 |
| Equus Environmental Limited | Extraterritorial | 2008 |
| Eraflage Ltd | Wholesale & retail | 2025 |
| Erdeelc APS Limited | Wholesale & retail | 2025 |
| Eretail Enterprise Ltd | Wholesale & retail | 2023 |
| Ergi Industries Ltd | Professional & scientific | 2024 |
| Ergi Materials Ltd | Manufacturing | 2024 |
| Ernest Rhone Productions Ltd | Information & communication | 2017 |
| Errington Legal Recruitment Limited | Administrative & support | 2013 |
| Ersiai Ltd | Information & communication | 2026 |
| ES International Developments Ltd | Real estate | 2017 |
| Esam Trading Limited | Other services | 2023 |
| Esbrand International Limited | Professional & scientific | 2016 |
| Escado Group Limited | Wholesale & retail | 2021 |
| Escape Rooms Cornwall Ltd | Arts & recreation | 2023 |
| Escape Time ST Ives Cornwall Ltd | Arts & recreation | 2025 |
| Eschatos International Ministries | Other services | 2025 |
| Eshborn Holdings Ltd | Financial services | 2026 |
| Eshborn Lettings Ltd | Real estate | 2026 |
| Eshreen Limited | Information & communication | 2021 |
| Esimpro UK Ltd | Information & communication | 2025 |
| Esinsa Limited | Information & communication | 2018 |
| Eskay Medical Ltd | Health & social care | 2023 |
| Eslem Cafe Ltd | Hospitality | 2024 |
| ESO World Ltd | Wholesale & retail | 2023 |
| Esoterica Entertainment Ltd | Arts & recreation | 2022 |
| Espg Properties Ltd | Real estate | 2025 |
| Essence Flow Ltd | Other services | 2024 |
| Essence of Bahama Isles Limited | Manufacturing | 2025 |
| Essensual Sports Therapy Ltd | Health & social care | 2024 |
| Essential Care (Organics) Limited | Manufacturing | 2006 |
| Essential Retail Ltd | Wholesale & retail | 2022 |
| Essex Dryliners Ltd | Construction | 2018 |
| Essr Limited | Wholesale & retail | 2020 |
| EST 1469 Ltd | Wholesale & retail | 2023 |
| Estates Creative Homes Limited | Real estate | 2017 |
| Esthetics-Uk Ltd | Other services | 2024 |
| Estrella Beauty & Aesthetics Ltd | Other services | 2023 |
| ET Excel Ltd | Health & social care | 2025 |
| ETA Nomad Ltd | Administrative & support | 2024 |
| Etalent Limited | Professional & scientific | 2003 |
| ETC Accommodation Ltd | Real estate | 2025 |
| ETC Group Ltd | Financial services | 2025 |
| Etcapara Limited | Professional & scientific | 2012 |
| Etech Academy Ltd | Education | 2024 |
| Eternal Weddings Films Limited | Manufacturing | 2025 |
| Ethan Property Investments Limited | Real estate | 2023 |
| Ethics International Multimedia Limited | Information & communication | 1999 |
| ETM Global Limited | Administrative & support | 2015 |
| Etna Road Leasehold Management Company 2019 Limited | Households | 2019 |
| Etot Consulting Limited | Other services | 2017 |
| ETR Ltd | Wholesale & retail | 2013 |
| EU Fulfilment Ltd | Transport & logistics | 2020 |
| Eudoxia BIO Ltd | Professional & scientific | 2024 |
| Eugene Bergmann Limited | Transport & logistics | 2012 |
| Eumo Tech Ltd | Information & communication | 2026 |
| Eunicare Health Ltd | Health & social care | 2024 |
| Eunoia Systems Limited | Information & communication | 2025 |
| Euro First Ltd | Real estate | 2003 |
| Euro Professional IT Consultants Ltd | Information & communication | 2026 |
| Euro-Food Machinery Limited | Wholesale & retail | 1987 |
| Euroasia UK Lettings Ltd | Real estate | 2026 |
| Euroducation Limited | Information & communication | 2022 |
| Eurodzd Services Ltd | Professional & scientific | 2026 |
| Eurofood Technology Limited | Extraterritorial | 1992 |
| Euromea Consult Ltd | Professional & scientific | 2025 |
| Europa B Ltd | Wholesale & retail | 2021 |
| Europa Bar and Club Ltd | Hospitality | 2017 |
| Europarts & Trucks (UK) Limited | Administrative & support | 2007 |
| Europe Associates Limited | Other services | 2023 |
| EV Analytics Limited | Professional & scientific | 2021 |
| EVA Gercas Coaching Ltd | Health & social care | 2023 |
| Evabloomfloral Ltd | Wholesale & retail | 2025 |
| Evad Global Ltd | Information & communication | 2013 |
| Evaluake Ltd | Professional & scientific | 2025 |
| Evander Services UK Ltd | Administrative & support | 2024 |
| Evangelos PAP Ltd | Transport & logistics | 2026 |
| Evanio Ltd | Information & communication | 2025 |
| Evelyn & Bloom Limited | Administrative & support | 2018 |
| Even Properties Limited | Real estate | 2020 |
| Evenhomes Property Management Ltd | Real estate | 2025 |
| Event & Bar Ltd | Wholesale & retail | 2021 |
| Event Extras Ltd | Other services | 2026 |