| Unique Boilers Ltd | Construction | 2014 |
| Unique Business Intelligence Limited | Information & communication | 2014 |
| Unique Grass Company Ltd | Construction | 2022 |
| Unique Play Company Ltd | Construction | 2022 |
| United Furniture (AB) Ltd | Manufacturing | 2016 |
| Unitedenergysolutions Limited | Construction | 2025 |
| Universal Collectibles Ltd | Wholesale & retail | 2023 |
| Universal Medical Limited | Health & social care | 2020 |
| Unseen Aware Limited | Professional & scientific | 2002 |
| Uppgraded Limited | Extraterritorial | 2018 |
| Uprite Scaffolding (NW) Ltd | Construction | 2025 |
| UPS Power Engineering Ltd | Information & communication | 2022 |
| UR MEP Design Ltd | Professional & scientific | 2026 |
| Uray Ltd | Wholesale & retail | 2020 |
| Urban Botanica Coffee Limited | Administrative & support | 2017 |
| Urban Craft Sofas Limited | Wholesale & retail | 2025 |
| Urban Woodhouse LLP | | 2024 |
| Used Parts Specialists Ltd | Other services | 2018 |
| Usethegeeks Limited | Information & communication | 2016 |
| Usha Bangladeshi Restaurant Ltd | Hospitality | 2025 |
| Usha Ltd | Hospitality | 2019 |
| Usin Services Ltd | Professional & scientific | 2012 |
| Usman Digital Marketing Services Ltd | Wholesale & retail | 2025 |
| Utopia IT Systems Limited | Wholesale & retail | 2020 |
| UV Magnets Ltd | Manufacturing | 2024 |
| UW Corporation Ltd | Wholesale & retail | 2025 |
| V Finds Trade Ltd | Wholesale & retail | 2025 |
| V R Locum Ltd | Health & social care | 2025 |
| V Smith T/A the Salon Ltd | Other services | 2012 |
| V.I.P Cutz Ltd | Other services | 2024 |
| V.I.P Driven Ltd | Other services | 2017 |
| V.J.B. Solutions Ltd | Health & social care | 2003 |
| Vabe Logistics Ltd | Transport & logistics | 2022 |
| Vale Broadband Limited | Information & communication | 2023 |
| Vale Communications Infrastructure Limited | Information & communication | 2023 |
| Vale Telecommunications Group Limited | Financial services | 2023 |
| Vale Telecommunications Holdings Limited | Financial services | 2024 |
| Validate My AGE Limited | Information & communication | 2020 |
| Valley Colour Ltd | Construction | 2026 |
| Valley Services Group Limited | Financial services | 2023 |
| Valley Slate Ltd | Construction | 2022 |
| Valley Speech Therapy Ltd | Health & social care | 2023 |
| Valley View Billington Ltd | Households | 2015 |
| Vanguard Law Ltd | Professional & scientific | 2016 |
| Vantage Events Ltd | Administrative & support | 2026 |
| Vantex (UK) Ltd | Manufacturing | 2003 |
| Vantira Care Ltd | Health & social care | 2023 |
| Vape Boys and Drinks Ltd | Wholesale & retail | 2025 |
| Vapes and Chai Ltd | Wholesale & retail | 2025 |
| Vapes and Shakes Burnley Ltd | Wholesale & retail | 2026 |
| Varartech Ltd | Other services | 2016 |
| Vardion Limited | Information & communication | 2025 |
| Varna Bulgaria Ltd | Wholesale & retail | 2025 |
| Varna Engineering Services Ltd | Construction | 2015 |
| Varnavas Enterprises Ltd | Construction | 2005 |
| Vault Cinemas Ltd | Information & communication | 2026 |
| VCG (4X4) Limited | Arts & recreation | 2008 |
| Vehicle Remarketing Specialist Ltd | Wholesale & retail | 2024 |
| Veka PLC | Manufacturing | 1982 |
| Velocity Composites PLC | Manufacturing | 2007 |
| Velocity Sports Partners Studios Limited | Information & communication | 2026 |
| Veloria Funeral Services Ltd | Other services | 2026 |
| Venom Power and Fitness Ltd | Arts & recreation | 2024 |
| Ventureprise ABC Limited | Administrative & support | 2013 |
| Ventureprise PLC | Administrative & support | 2014 |
| Venty Holdings Limited | Financial services | 2026 |
| Vepco Limited | Information & communication | 2009 |
| Verdi's ST Albans Limited | Hospitality | 2017 |
| Verephi Ltd | Professional & scientific | 2013 |
| Vericare Lancashire Limited | Public administration | 2026 |
| Vertex Agency Limited | Professional & scientific | 2025 |
| Vertex Distribution Limited | Professional & scientific | 2024 |
| Vertex Media Group Limited | Professional & scientific | 2024 |
| Vesty (Holdings) Limited | Professional & scientific | 1984 |
| Vesty (UK) Limited | Wholesale & retail | 2001 |
| VF Simonstone Limited | Agriculture & fishing | 2025 |
| VG Accountancy Ltd | Professional & scientific | 2023 |
| VG Investment Group Ltd | Financial services | 2021 |
| Vicki Shotbolt Class Representative Limited | Other services | 2023 |
| Victoria Apartments (Padiham) Limited | Real estate | 1995 |
| Victoria Car Wash Ltd | Administrative & support | 2024 |
| Victoria Eurapea Mini Market Limited | Wholesale & retail | 2025 |
| Victoria Linen Company Limited | Manufacturing | 2006 |
| Vida Futura Limited | Financial services | 2020 |
| Vienna Capital Management Ltd | Professional & scientific | 2014 |
| Vikiin Property & Lettings Limited | Wholesale & retail | 2022 |
| Vincent Leisure Ltd | Other services | 2021 |
| Vincents (Wigan) LLP | | 2019 |
| Vinmak Limited | Transport & logistics | 2016 |
| Vintage ERA Limited | Wholesale & retail | 2025 |
| VIP Cuts Burnley Limited | Other services | 2025 |
| VIP Nails 18 Ltd | Other services | 2023 |
| Virtus Kickboxing Limited | Arts & recreation | 2024 |
| Viscount Headboards Limited | Manufacturing | 1986 |
| Visibility Leads Limited | Professional & scientific | 2017 |
| Vision Care Lancashire Limited | Health & social care | 2025 |
| Vision Graphics UK Ltd | Professional & scientific | 2022 |
| Vision Prestige Ltd | Transport & logistics | 2021 |
| Vistaar Ltd | Wholesale & retail | 2024 |
| Vita World Limited | Wholesale & retail | 2026 |