| Daisy & DOT Co Limited | Wholesale & retail | 2022 |
| Daisy Matthews Ltd | Professional & scientific | 2019 |
| Dale Contractors Limited | Construction | 1986 |
| Dales Properties Limited | Real estate | 2002 |
| Dalry Developments Ltd | Real estate | 2025 |
| Daneshouse Community Partnership Ltd | Public administration | 2024 |
| Daneshouse Family Wellbeing Centre Ltd | Administrative & support | 2026 |
| Daniel Adesanya Limited | Health & social care | 2021 |
| Daniel Construction Limited | Construction | 2019 |
| DAR Assets Ltd | Real estate | 2026 |
| Darlington Properties Ltd | Construction | 2023 |
| Data Day Solutions Ltd | Information & communication | 2024 |
| Datacrown Limited | Information & communication | 1983 |
| Datapro Connect Limited | Information & communication | 2008 |
| Datum Finance Limited | Financial services | 2005 |
| Datum Property Developments Limited | Construction | 2009 |
| Datum Property Holdings Limited | Construction | 2008 |
| David & Co. Property Management Ltd | Financial services | 2014 |
| David & Co. Traders Ltd | Construction | 2014 |
| David Breaks Livestock Ltd | Agriculture & fishing | 2020 |
| David Horrocks Consultancy Ltd | Professional & scientific | 2022 |
| David Marsden Limited | Wholesale & retail | 1999 |
| David Mcclymont Limited | Professional & scientific | 2003 |
| David Nicholas Construction Ltd | Construction | 2020 |
| David Ogden Consultancy Services Limited | Professional & scientific | 2024 |
| David Thornton Financial Services Limited | Financial services | 2016 |
| Davidson Joinery Ltd | Construction | 2015 |
| Davies Knight Limited | Administrative & support | 2013 |
| Dawn to Dusk (Worsthorne Primary) Ltd | Health & social care | 2009 |
| Dawn to Dusk Burnley Limited | Health & social care | 2018 |
| Day Night Travels Ltd | Administrative & support | 2024 |
| Daywell Services Limited | Health & social care | 2022 |
| DB Associates (NW) Ltd | Real estate | 2005 |
| DB Contracting (Electrical Services) Ltd | Construction | 2016 |
| DB Data Comms Limited | Information & communication | 2005 |
| DB Data Comms Trustee Ltd | Professional & scientific | 2025 |
| DBS Commodity Consultants Limited | Financial services | 2018 |
| DC Electrical & Controls Ltd | Construction | 2019 |
| DC Electrics Ltd | Manufacturing | 2023 |
| DC Properties (Northwest) Limited | Households | 2023 |
| DC Unique Properties Ltd | Real estate | 2025 |
| Dcis Consultancy Limited | Other services | 2012 |
| DCL Holdings Lancashire Ltd | Households | 2026 |
| DCR Decorating Ltd | Construction | 2022 |
| DDS Events & Merchandise Ltd | Wholesale & retail | 2025 |
| DE Suin Wood Ltd | Real estate | 2025 |
| Deals Square Ltd | Wholesale & retail | 2025 |
| Dean Mill Limited | Construction | 1992 |
| Dean Street Alternative School Ltd | Education | 2020 |
| Dearden Plumbing & Heating Ltd | Construction | 2025 |
| Debonhair Ltd | Other services | 2018 |
| Decorum Maintenance and Construction Ltd | Construction | 2022 |
| Dedicated Software Solutions Limited | Information & communication | 2016 |
| Deecoa Solutions Limited | Professional & scientific | 2012 |
| Deeej Ltd | Information & communication | 2026 |
| Defined Services (UK) Ltd | Other services | 2013 |
| DEL (NW) Ltd | Wholesale & retail | 2026 |
| DEL Boyz Logistics Limited | Transport & logistics | 2025 |
| Deli Touch(Burnley) Ltd | Hospitality | 2021 |
| Delicious Pizza Kebab Ltd | Hospitality | 2019 |
| Delm Digital Limited | Information & communication | 2023 |
| Delphi Medical Limited | Health & social care | 2009 |
| Delta Building & Construction (Rossendale) Limited | Construction | 2024 |
| Delta Fire Marshals Ltd | Administrative & support | 2025 |
| Delta Watch Security Ltd | Administrative & support | 2022 |
| Deluxe Home Interiors Limited | Manufacturing | 2020 |
| Dementia Care TLC Limited | Health & social care | 2018 |
| Dennis Baldwin Group Ltd | Professional & scientific | 2008 |
| Dennis Baldwin Properties Limited | Financial services | 2017 |
| Derby Skillbuild | Education | 2007 |
| Derek"S Logistics Solutions Ltd | Transport & logistics | 2024 |
| Desi District Ltd | Hospitality | 2026 |
| Desivibes Ltd | Wholesale & retail | 2025 |
| Destino Homes Ltd | Real estate | 2023 |
| Detec Security Limited | Extraterritorial | 2007 |
| Deudraa UK Limited | Information & communication | 2018 |
| Device Care & Vapes Ltd | Wholesale & retail | 2023 |
| Devine Ultrasound Care Ltd | Health & social care | 2023 |
| Dhaka City Catering Ltd | Hospitality | 2025 |
| Dhaka City Ltd | Hospitality | 2025 |
| Diamond Contract Cleaners Ltd. | Administrative & support | 2007 |
| Diamond Cuts 365 Limited | Other services | 2023 |
| Diamond Deal Sourcing Ltd | Households | 2025 |
| Diamond Notary Ltd | Professional & scientific | 2020 |
| Dianne's Delicacies Ltd | Hospitality | 2024 |
| Dibas Deli Ltd | Hospitality | 2023 |
| Dickinson & Company Limited | Financial services | 2002 |
| Diesel DES Ltd | Wholesale & retail | 2026 |
| Dieter Allen Consulting Limited | Professional & scientific | 2015 |
| Digital Fashion Photography Ltd | Professional & scientific | 2015 |
| Digital Kingdom Ltd | Wholesale & retail | 2021 |
| Digital Novatech Ltd | Wholesale & retail | 2025 |
| Digonyx Ltd | Professional & scientific | 2025 |
| Dillon Properties (North West) Limited | Construction | 2012 |
| Dima Trova Limited | Wholesale & retail | 2024 |
| Direct Acquisitions Group Ltd | Information & communication | 2025 |
| Direct Gardens & Driveways Ltd | Construction | 2019 |
| Direct Material Handling Ltd | Manufacturing | 2015 |
| Direct Self Storage Limited | Real estate | 2015 |
| Direct Vans Limited | Transport & logistics | 2019 |