| RB Air-Conditioning Ltd | Energy | 2022 |
| RB People Consultants Ltd | Professional & scientific | 2024 |
| Rccg - the Joy of ALL Souls | Other services | 2011 |
| RDP Group (UK) Limited | Manufacturing | 2000 |
| RDP Health Limited | Extraterritorial | 2014 |
| Re-Engineered Landscaping Ltd | Administrative & support | 2023 |
| Reactive Surveys Limited | Professional & scientific | 2014 |
| Real Health & Aesthetics Ltd | Other services | 2025 |
| Real Piercing & Tattoo Ltd | Other services | 2020 |
| Rebel Creative Agency Ltd | Information & communication | 2025 |
| Recruitvirt Limited | Administrative & support | 2012 |
| Red Chimp Media Ltd | Information & communication | 2023 |
| Red INK Publishing Ltd | Information & communication | 2015 |
| Red Wolf Security Ltd | Administrative & support | 2025 |
| Redhead Design Limited | Professional & scientific | 2003 |
| Redleaf Financial Planning LLP | | 2024 |
| Redmond Electrical & Renewables Limited | Construction | 2021 |
| Reeves Fascia Soffits Gutters Specialist Limited | Manufacturing | 2025 |
| Reeves Roofers Ltd | Construction | 2021 |
| Referencing Hub Ltd | Administrative & support | 2026 |
| Regal Silver Ltd | Manufacturing | 2019 |
| Regenerate Cities Limited | Professional & scientific | 2023 |
| Regenerate ESG Limited | Professional & scientific | 2023 |
| Rehearsal Orchestra (the) | Education | 1964 |
| Reliable FM Limited | Administrative & support | 2025 |
| Reliable Maintenance Limited | Construction | 2003 |
| Remote Graphics Ltd | Administrative & support | 2016 |
| Remould Performance Ltd | Education | 2025 |
| Residents Association(Burgess Hill)Limited | Households | 1959 |
| Resilient Beings Ltd | Extraterritorial | 2019 |
| Respect Plus Ltd | Health & social care | 2012 |
| Restocked TCG Ltd | Wholesale & retail | 2026 |
| Retain Digital Limited | Administrative & support | 2018 |
| Retire by Design Ltd | Financial services | 2024 |
| Revamp Autoworks & Customs Limited | Wholesale & retail | 2018 |
| Revamp Mechanical Services Limited | Wholesale & retail | 2017 |
| Revive Home and Garden Limited | Administrative & support | 2019 |
| Reyhan Remedies Ltd | Wholesale & retail | 2025 |
| RGC Freehold Limited | Households | 2019 |
| RGG Ventures Ltd | Financial services | 2026 |
| Richard James Building Contractors Limited | Construction | 2021 |
| Ridgeway Aesthetics Ltd | Other services | 2024 |
| Ridl Civil Engineering Ltd | Professional & scientific | 2026 |
| Ridl Ltd | Construction | 2024 |
| Ringdale Deutschland Limited | Information & communication | 1984 |
| Ringdale Technology Limited | Professional & scientific | 1989 |
| Rise Prosperity Properties Ltd | Real estate | 2024 |
| River House (London) Ltd | Construction | 2006 |
| Riverjuke Limited | Arts & recreation | 2014 |
| Rjbcc Ltd | Construction | 2025 |
| RJF & Sons Ltd | Administrative & support | 2014 |
| RJF Property Enterprises Ltd | Construction | 2024 |
| RJS Consultants Limited | Information & communication | 2003 |
| RJS Family Homes Limited | Information & communication | 2006 |
| ROB GEE Ltd | Wholesale & retail | 2022 |
| Robert James Builders Limited | Construction | 2025 |
| Robert Simpson Construction Limited | Construction | 2008 |
| Robinson Heating & Plumbing Limited | Construction | 2017 |
| Robuck Aero Engineering Limited | Professional & scientific | 1997 |
| Roche Diabetes Care Limited | Administrative & support | 2014 |
| Roden Technology Limited | Manufacturing | 2014 |
| Roel's Car Wash Ltd | Other services | 2016 |
| ROL Food Limited | Hospitality | 2025 |
| Roma Healthcare Limited | Health & social care | 2013 |
| Rome Holdings Ltd | Financial services | 2020 |
| Rome Industries Ltd | Wholesale & retail | 2012 |
| Rosanne Florists Ltd | Wholesale & retail | 2026 |
| Roseleigh Management Company Limited | Households | 1990 |
| Rosie's Barbers Ltd | Other services | 2019 |
| Rosscoe Consulting Limited | Professional & scientific | 2018 |
| Rosy Gardens Limited | Administrative & support | 2024 |
| ROY and Carole Ltd | Real estate | 2009 |
| RP Products Limited | Manufacturing | 1999 |
| RPM Media Limited | Information & communication | 2015 |
| RS Film Services Ltd | Administrative & support | 2018 |
| RSB Security Limited | Administrative & support | 2015 |
| Rubid Ltd | Wholesale & retail | 2023 |
| Ruby Ruth Dolls Limited | Wholesale & retail | 2018 |
| Rudge House (Management) Limited | Households | 2004 |
| Russ Little Roofing Limited | Construction | 2024 |
| RWL Plumbing & Heating Ltd | Construction | 2014 |
| Ryde Court (Hove) Ltd | Households | 2000 |
| Ryecroft Flats Management Co. Limited | Real estate | 1978 |
| RZW Estates Ltd | Extraterritorial | 2023 |
| S & P International Limited | Wholesale & retail | 2018 |
| S E Home Improvements Ltd | Construction | 2026 |
| S&T Controls Limited | Manufacturing | 2008 |
| S.M. Johnson & Co. Limited | Professional & scientific | 2003 |
| S4CHU Holdings Ltd | Financial services | 2025 |
| SA Contractors Building & Electrical Ltd | Construction | 2018 |
| SA FFF Coaching LLP | | 2025 |
| Sadhana Hairdressing Limited | Other services | 2007 |
| Safari Butler Limited | Administrative & support | 2021 |
| Saffron Star International Ltd | Professional & scientific | 2014 |
| Sally Williams Architects Ltd | Professional & scientific | 2012 |
| SAM Harries Consulting Limited | Public administration | 2016 |
| Samjnsn Ltd | Professional & scientific | 2020 |
| Sankalpa Services Ltd | Wholesale & retail | 2023 |
| Saphire Doors Limited | Construction | 2006 |
| Sapphire Supplies Limited | Wholesale & retail | 2023 |