| Megarax Limited | Transport & logistics | 2002 |
| Meldon Court Management Company Limited | Hospitality | 1990 |
| Merchant House Antiques Ltd | Wholesale & retail | 2003 |
| Meredith Morgan Taylor Ltd | Financial services | 2020 |
| Michael & Jean Vaughan (Devon) Limited | Real estate | 1975 |
| Michael Farley Organ Builders Ltd | Other services | 2018 |
| Michaels & Co Estate Planning Ltd | Other services | 2024 |
| Mike Marsh Mastering Limited | Information & communication | 2014 |
| Mill Tree Ltd | Agriculture & fishing | 2025 |
| Mk-Ultra Ltd | Wholesale & retail | 2008 |
| MOB Rule Ltd | Information & communication | 2025 |
| Molecule Beverages Ltd | Professional & scientific | 2012 |
| Motoreg Private Number Plates Limited | Wholesale & retail | 2026 |
| MR T A-Z Ltd | Information & communication | 2025 |
| Mulberry Architectural Services Ltd | Professional & scientific | 2002 |
| MWA Nominees Limited | Professional & scientific | 2018 |
| My Life in a Day Limited | Information & communication | 2015 |
| Nakedmaids Southwest Limited | Administrative & support | 2019 |
| Neurodevon Limited | Administrative & support | 2023 |
| Ninefold Management Company (Budleigh Salterton) Limited | Households | 1979 |
| NLD SW Limited | Construction | 2012 |
| Number 4 Camden Crescent Bath Limited | Real estate | 1992 |
| Oak Lodge Cafe LLP | | 2021 |
| Oak Tree Budleigh Limited | Households | 2017 |
| Oakfield Businesses Limited | Other services | 2016 |
| Oakhill (East Budleigh) Residents Limited | Households | 2008 |
| Ocean Insight Limited | Professional & scientific | 2004 |
| Odds Hawk Ltd | Information & communication | 2020 |
| Odirect Holdings Limited | Information & communication | 2021 |
| Odirect Limited | Information & communication | 2021 |
| Odirect Marketing Limited | Information & communication | 2021 |
| Only Eight Limited | Wholesale & retail | 2023 |
| Otcgb Ltd | Wholesale & retail | 2017 |
| Otter Valley Funerals Ltd | Other services | 2021 |
| P&F Consulting Limited | Professional & scientific | 2007 |
| Palm Court (Budleigh Salterton) Management Company Limited | Real estate | 2001 |
| Palmer Court Management Company Limited | Households | 1983 |
| Palmer House (Management) Limited | Households | 2003 |
| Paritor Holdings Limited | Administrative & support | 2011 |
| Paritor Limited | Administrative & support | 2017 |
| Park Lodge (Devon) RTM Company Limited | Households | 2004 |
| Parkside Consultants Limited | Financial services | 2015 |
| Pathfinder Sales Ltd | Professional & scientific | 2015 |
| PEG 4 Ltd | Financial services | 2025 |
| Perfect 14 Ltd | Information & communication | 2013 |
| Personal Touch Embroidery Co Limited | Wholesale & retail | 2005 |
| Personalisedgiftuk Limited | Wholesale & retail | 2018 |
| Pets Lover Limited | Wholesale & retail | 2018 |
| Piers Motley Auctions Limited | Wholesale & retail | 2010 |
| Pinnacle Property Holdings Ltd | Real estate | 2023 |
| Pipeline Plant Solutions Ltd | Manufacturing | 2024 |
| Pjcvision Ltd | Professional & scientific | 2005 |
| Predictive Edge Ltd | Information & communication | 2018 |
| Premier Discount Warehouses Limited | Real estate | 1974 |
| Premier Electrical Centres Limited | Real estate | 1983 |
| Prestige Yacht Services Ltd | Other services | 2020 |
| Pro Speakers Limited | Administrative & support | 2022 |
| Pro-Heat Plumbing and Heating Contractors Limited | Construction | 2013 |
| PS03 Holdings Limited | Financial services | 2022 |
| PS03 Properties Ltd | Real estate | 2022 |
| Raleigh Construction Ltd | Construction | 2022 |
| Raleigh Property Investment Limited | Professional & scientific | 2020 |
| Regis Estates Ltd | Construction | 2020 |
| Richard Smythe AV Limited | Wholesale & retail | 2015 |
| Robert Mcblain Property Solutions Ltd | Hospitality | 2015 |
| Robert Mcblain Solutions Ltd | Professional & scientific | 2010 |
| Rolle Barton Limited | Households | 1999 |
| Rowanhays Ltd | Manufacturing | 2014 |
| S COX & Co Ltd | Construction | 2013 |
| S3 Contract Solutions Limited | Professional & scientific | 2013 |
| SA Holdings Exeter Limited | Financial services | 2021 |
| Sabia Duvida Limited | Education | 2020 |
| Saffron Court Limited | Households | 1982 |
| Salterne Meadow Management Limited | Real estate | 2002 |
| Sand Dog Design Limited | Administrative & support | 2009 |
| Saxmere Limited | Real estate | 2025 |
| Scan Maritime Limited | Professional & scientific | 2014 |
| Schooble Limited | Extraterritorial | 2013 |
| Scrub Bunnies Ltd | Information & communication | 2025 |
| Sculler Holdings Ltd | Real estate | 2021 |
| Sea Swim Devon CIC | Education | 2024 |
| Seaton Town Garage Ltd. | Wholesale & retail | 1998 |
| SGL Computers Limited | Wholesale & retail | 2018 |
| Simply Fostering Consultancy Ltd | Administrative & support | 2013 |
| Sky Property Investment Limited | Real estate | 2020 |
| Slink Inc Limited | Arts & recreation | 2010 |
| SLS Rehab Ltd | Health & social care | 2018 |
| SM Accountancy Services (South West) Ltd | Professional & scientific | 2022 |
| Soul Sanctuary Teacher Training Ltd. | Education | 2017 |
| Soul Sanctuary Yoga CIC | Arts & recreation | 2015 |
| South Beach Spa Ltd | Other services | 2018 |
| South West Shipping Worldwide Limited | Professional & scientific | 2005 |
| Southern Food Services Limited | Hospitality | 2024 |
| Speaker Express UK Ltd | Other services | 2015 |
| Ssas Administration Services Ltd | Financial services | 2023 |
| Start Lettings Limited | Real estate | 2020 |
| Sterry Family Limited | Real estate | 2020 |
| Sunflower Learning Limited | Information & communication | 2002 |
| SW Partners Ltd | Administrative & support | 2021 |
| Sweet Structures Ltd | Professional & scientific | 2021 |