| Panpower Engineering Ltd | Professional & scientific | 2023 |
| Parker Mitchell Limited | Information & communication | 2014 |
| Paul Male Appliance Repairs Ltd. | Other services | 2003 |
| PDK DOD Limited | Health & social care | 2010 |
| Pennywell Leisure Limited | Arts & recreation | 2008 |
| People Dynamics Limited | Professional & scientific | 2022 |
| Peptiology Ltd | Wholesale & retail | 2024 |
| Phoenix Fire Consultancy Ltd | Professional & scientific | 2007 |
| Phoenix Property Consultants Limited | Hospitality | 2011 |
| Phoenix Will Writing Limited | Other services | 2026 |
| Plum Hair Limited | Other services | 2026 |
| Pole Position Scaffolding SW Ltd | Construction | 2018 |
| Primoplast Plastering Contractors Ltd | Construction | 2014 |
| Professional Construction Solutions South West Limited | Construction | 2006 |
| Progas Devon Ltd | Construction | 2022 |
| Project 637 Ltd | Information & communication | 2023 |
| Projective Engineering Ltd | Manufacturing | 2011 |
| Purex Global Limited | Manufacturing | 2019 |
| Purex Holdings Limited | Financial services | 2019 |
| R J Brooks & SON Limited | Construction | 2001 |
| Rasson Properties Ltd | Real estate | 2019 |
| Ratio Studio Ltd | Information & communication | 2025 |
| Redstone Renovations & Landscaping Ltd | Construction | 2024 |
| Reinvent Engineering Limited | Professional & scientific | 2025 |
| Retrovation Ltd | Wholesale & retail | 2020 |
| RFP Fowey Limited | Manufacturing | 2015 |
| RFP Marazion Limited | Wholesale & retail | 2020 |
| RFP Newquay Ltd | Wholesale & retail | 2014 |
| RFP Padstow Limited | Manufacturing | 2015 |
| RFP Tintagel Ltd | Wholesale & retail | 2019 |
| Riverbank Digital Limited | Information & communication | 2025 |
| Riverford Employee Ownership Trustee Limited | Extraterritorial | 2017 |
| Riverford Organic Farmers Limited | Agriculture & fishing | 1999 |
| Riverford Organic Vegetables Limited | Extraterritorial | 2012 |
| ROB Muscutt Limited | Financial services | 2009 |
| Robin RAY Ltd | Other services | 2008 |
| Robinsons UK Heating Academy South Ltd | Education | 2025 |
| Rokura Ltd | Wholesale & retail | 2026 |
| Ronson Maritime Security Services Limited | Administrative & support | 2009 |
| Roofing Slate Ltd | Wholesale & retail | 2009 |
| Rosefinch Limited | Households | 1996 |
| Ruby's Ice Cream Newquay Ltd | Wholesale & retail | 2025 |
| Ruby's Ice Cream Parlour Marazion Limited | Wholesale & retail | 2020 |
| Ruby's Ice Cream Production Ltd | Manufacturing | 2025 |
| Rubys Ice Cream Parlour Limited | Wholesale & retail | 2020 |
| Rubys Ice Cream Parlour Mevagissey Limited | Wholesale & retail | 2024 |
| Ruby’S Ice Cream Padstow Ltd | Wholesale & retail | 2026 |
| Sanctuary 24 Limited | Administrative & support | 2016 |
| Sanremo UK Limited | Wholesale & retail | 2016 |
| SBB Property Improvements Limited | Construction | 2017 |
| School House Tearoom Cockington Limited | Hospitality | 2022 |
| Scops Drinks Limited | Manufacturing | 2010 |
| Scoriton Hydro Ltd | Energy | 2009 |
| Seed Sowers Trust | Water & waste | 2000 |
| Shine Thrive Ltd | Health & social care | 2023 |
| Sigma Design Ltd | Wholesale & retail | 2023 |
| Signature Developments SW Ltd | Construction | 2024 |
| Signature Masonry Ltd | Construction | 2018 |
| Silverlake Property Ltd | Construction | 2025 |
| Skylark Sounds Ltd | Information & communication | 2017 |
| Smifam Ashburton Limited | Professional & scientific | 1995 |
| Soundtracker Ltd | Information & communication | 2024 |
| South Devon Railway Association Limited | Other services | 2017 |
| South Devon Railway Engineering Limited | Manufacturing | 2008 |
| South Devon Railway Retail and Catering Limited | Wholesale & retail | 2019 |
| South Devon Railway Road Services Limited | Transport & logistics | 2012 |
| South Herts Electrical Limited | Manufacturing | 2009 |
| Spence Property Solutions Ltd | Real estate | 2018 |
| ST. Benedict Care Trust | Health & social care | 2022 |
| Stage Exeter Limited | Hospitality | 2026 |
| Stanford Holding Ltd | Real estate | 2020 |
| Starjar Limited | Information & communication | 2003 |
| Station Cabs Totnes Ltd | Transport & logistics | 2024 |
| Stcw Fire Training Ltd | Education | 2018 |
| Stcw Training Ltd | Education | 2024 |
| Stcw Training UK Limited | Transport & logistics | 2006 |
| Steve Doyle Electrical Ltd | Construction | 2019 |
| Stoke Physiotherapy Ltd | Health & social care | 2010 |
| TB Champions CIC | Other services | 2025 |
| Teague Property SW Ltd | Real estate | 2025 |
| Thackard Holdings Limited | Financial services | 2021 |
| Thackard Limited | Other services | 1999 |
| THB Accountants Ltd | Professional & scientific | 2021 |
| THE Battisborough Charitable Trust | Health & social care | 1960 |
| THE Bell House Cutter's Limited | Other services | 2025 |
| THE Body Happy Organisation CIC | Education | 2020 |
| THE Cockington GIN Company Ltd | Wholesale & retail | 2024 |
| THE Good Guys Consultants Ltd | Professional & scientific | 2022 |
| THE Hair Lounge SW Ltd | Other services | 2013 |
| THE Media Workshop Ltd | Information & communication | 2011 |
| THE Ottery Flooring Company Ltd | Wholesale & retail | 2021 |
| THE REX Asset Group Ltd | Financial services | 2024 |
| THE Rock Care Home Ltd | Health & social care | 2020 |
| THE Seed - Buckfastleigh Community Wholefood Store C.I.C. | Wholesale & retail | 2013 |
| THE Silent Whistle Ashburton Ltd | Hospitality | 2026 |
| THE Story Behind the Silence Limited | Health & social care | 2025 |
| THE Yard (Creative Space) Ltd | Arts & recreation | 2025 |
| Thomas Dixon Ltd | Construction | 2024 |
| Tizzle Zizzle App Ltd | Information & communication | 2014 |
| Torridge Stores Ltd | Wholesale & retail | 2015 |