| Umech Consultancy Services Limited | Professional & scientific | 2025 |
| Umlaut Developments Ltd | Real estate | 2021 |
| Uncle's Tuition Limited | Education | 2022 |
| Uneco Ltd | Construction | 2024 |
| Unflatpack Ltd | Construction | 2011 |
| Unica Coaching & Consulting Ltd | Professional & scientific | 2023 |
| Unico Gelato & Caffe Ltd | Wholesale & retail | 2015 |
| Uniconsulting Limited | Administrative & support | 2016 |
| Unify Experiences Limited | Arts & recreation | 2023 |
| Unify Productions Global Ltd | Arts & recreation | 2021 |
| Union Hairdressing Salon Limited | Other services | 2001 |
| Union Properties Group Ltd | Real estate | 2021 |
| Union Scaffolding and Roofing Limited | Construction | 2024 |
| Unique Atlantic Seafood Limited | Wholesale & retail | 2013 |
| Unique Bitz Ltd | Wholesale & retail | 2025 |
| Unique Blue Ltd | Extraterritorial | 2026 |
| Unique Hair Ltd | Other services | 2023 |
| Unique Prop Hire Ltd | Wholesale & retail | 2021 |
| Unique Seafood (East) Limited | Wholesale & retail | 2004 |
| Unique Seafood Holdings Limited | Financial services | 2013 |
| Unique Seafood Limited | Wholesale & retail | 1997 |
| Unique Seafood Pelagic Limited | Wholesale & retail | 2007 |
| Uniquesally Ltd | Other services | 2020 |
| Unite Group Holdings Limited | Real estate | 2024 |
| United Influence Limited | Professional & scientific | 2026 |
| United Mechanical Services Limited | Construction | 2016 |
| United Networks (Satellite) Ltd | Information & communication | 2001 |
| United Property Services (UPS) Ltd | Real estate | 2020 |
| United Radio Ltd | Information & communication | 2021 |
| United Skills Centre Ltd | Education | 2025 |
| Unity 23 Fitness Ltd | Arts & recreation | 2024 |
| Unity Commerce Group Ltd | Wholesale & retail | 2024 |
| Universal Mechanical Services Limited | Construction | 2013 |
| Uniwave Limited | Administrative & support | 2017 |
| Unspun Advisory Ltd | Professional & scientific | 2026 |
| UOI Limited | Financial services | 2003 |
| UP Worldwide Limited | Administrative & support | 2023 |
| Upper East Side Limited | Real estate | 2019 |
| Uprise Roofing Ltd | Construction | 2026 |
| Upside Logistics Ltd | Transport & logistics | 2026 |
| Upteam Solutions Ltd | Hospitality | 2023 |
| Urban and Country Developments Ltd | Professional & scientific | 2012 |
| Urban Aura Stays Ltd | Hospitality | 2025 |
| Urban Birds Limited | Information & communication | 2012 |
| Urbanrise Property Solutions Ltd | Real estate | 2024 |
| Urbanvolt Electrical Ltd | Manufacturing | 2025 |
| Urology UK Limited | Professional & scientific | 2016 |
| Utilityflow Limited | Administrative & support | 2010 |
| Utmost Trading (UK) Ltd | Manufacturing | 2024 |
| UV Events Ltd | Arts & recreation | 2024 |
| UV Logic Limited | Manufacturing | 2020 |
| UVT Consultancy Ltd | Health & social care | 2021 |
| Uxgateway Limited | Other services | 2015 |
| V Jenkins Services Limited | Administrative & support | 2018 |
| V T Fitness Limited | Arts & recreation | 2019 |
| V&A Training Limited | Education | 2020 |
| V&C Services Limited | Professional & scientific | 2008 |
| V&K Invest Ltd | Health & social care | 2018 |
| V'S Gleam Team Ltd | Administrative & support | 2025 |
| V.A.D. Drywall Ltd | Construction | 2010 |
| V.Akela Ltd | Construction | 2019 |
| VAA Collections Ltd | Transport & logistics | 2012 |
| Vaana Foods Ltd | Wholesale & retail | 2020 |
| Vaaron Limited | Wholesale & retail | 2019 |
| Vaartek Limited | Information & communication | 2024 |
| VAH (DIY) Limited | Construction | 2008 |
| Vainnov Ltd | Professional & scientific | 2013 |
| Valdasta Ltd | Construction | 2018 |
| Vale Lodge RTM Company Limited | Households | 2009 |
| Vale Road Residents Ltd | Other services | 2007 |
| Vale Vale Ltd | Information & communication | 2023 |
| Valensole Enterprises Limited | Other services | 2019 |
| Valensole Group Limited | Professional & scientific | 2015 |
| Valerie Norman Casting Limited | Administrative & support | 2023 |
| Valhalla Software Limited | Information & communication | 2008 |
| Validatech Ltd | Professional & scientific | 2023 |
| Valley Delivery Company Limited | Administrative & support | 2014 |
| Valley Health Limited | Information & communication | 2021 |
| Valley Transports Limited | Transport & logistics | 2022 |
| Valley View Fencing & Tree Care Ltd | Agriculture & fishing | 2019 |
| Vallilingam Foods Services Limited | Hospitality | 2024 |
| Valo Safety Solutions Ltd | Professional & scientific | 2026 |
| Valora Advisory Ltd | Professional & scientific | 2026 |
| Valued Wellbeing Limited | Health & social care | 2022 |
| Vamos Catering Limited | Hospitality | 2014 |
| Van DER Werf - Assets & Holdings Ltd. | Financial services | 2024 |
| Van Hooijdonk Aesthetic Smiles Limited | Health & social care | 2024 |
| Vanguard Reseau Ltd | Information & communication | 2025 |
| Vanquish Plumbing and Heating Limited | Construction | 2021 |
| Vantage Consult Ltd | Information & communication | 2012 |
| Vantage Heights Management Limited | Real estate | 2009 |
| Vantage Point Management Limited | Households | 2010 |
| Vape HQ Swansea Limited | Wholesale & retail | 2023 |
| Varcoe Road Management Company Limited | Households | 2019 |
| Vasirom Limited | Transport & logistics | 2016 |
| Vassel Group Ltd | Health & social care | 2022 |
| Vat&Tax Ltd | Professional & scientific | 2021 |
| Vativa.Io Limited | Administrative & support | 2020 |
| Vayu Advanced Air Mobility Ltd | Manufacturing | 2026 |
| Vayu Logistics Ltd | Transport & logistics | 2025 |