| Silverdell Limited | Real estate | 2026 |
| Sims Property Management Limited | Real estate | 2025 |
| Simsek Mobile Barber Ltd | Other services | 2024 |
| Simulation Training Associates Limited | Professional & scientific | 1994 |
| Sincloco Ltd | Wholesale & retail | 2025 |
| Singing Hair Club Ltd | Other services | 2024 |
| SIP OR MIX Ltd | Wholesale & retail | 2011 |
| Siya Transport Ltd | Transport & logistics | 2026 |
| SK8 Thanet CIC | Education | 2026 |
| Skate Climb & Action Sports Kent CIC | Education | 2024 |
| Skin and Moore Ltd | Health & social care | 2024 |
| Skin and Tonic Kent Ltd | Other services | 2025 |
| SKIP2BFIT Ltd | Education | 2002 |
| SKIP4HEALTH CIC | Wholesale & retail | 2025 |
| Sky and Sand Ltd | Real estate | 2024 |
| Skytag Limited | Administrative & support | 2009 |
| Slimeology UK Ltd | Arts & recreation | 2025 |
| SLL Ventures Limited | Wholesale & retail | 2021 |
| Slow Beam Ltd | Wholesale & retail | 2022 |
| Sm-Vision Ltd. | Information & communication | 2018 |
| Smallbone Interiors Limited | Manufacturing | 2009 |
| Smallhub Ltd | Information & communication | 2008 |
| Smarter Outcomes Limited | Administrative & support | 2017 |
| Smiths Townhouse Limited | Hospitality | 2025 |
| Smoked Broadstairs Limited | Hospitality | 2023 |
| SMW Barbers Ltd | Other services | 2025 |
| Snapfax Property Management Company Limited | Hospitality | 1990 |
| Sneakerexposure Limited | Wholesale & retail | 2018 |
| SNH Trade Centre Limited | Wholesale & retail | 2017 |
| SNH Trade Limited | Financial services | 2026 |
| Snow Leopard Data Warehousing Ltd | Information & communication | 2016 |
| Snow Leopard Products Ltd | Wholesale & retail | 2016 |
| Socair Ltd | Professional & scientific | 2021 |
| Somerwolff Games Limited | Information & communication | 2023 |
| Sorted MEN Ltd | Wholesale & retail | 2026 |
| Soulsound School Limited | Education | 2013 |
| South Coast Pure Water Ltd | Water & waste | 2026 |
| South Coast Vessel Services Limited | Administrative & support | 2024 |
| South Eastern Road Limited | Households | 2021 |
| South Eastern Road Management Company Limited | Households | 2018 |
| Southern Antennae Limited | Manufacturing | 1983 |
| Southern Locomotives Hire Limited | Administrative & support | 2015 |
| Southern Locomotives Limited | Manufacturing | 1990 |
| Southwood Way Limited | Other services | 2021 |
| Sowell Street Ltd | Hospitality | 2020 |
| Spacer | Professional & scientific | 2017 |
| Sparaxis Limited | Other services | 2023 |
| Sparrow Legs Limited | Manufacturing | 2014 |
| Sparsholt Property Ltd | Financial services | 2020 |
| SPD Comparisons Limited | Professional & scientific | 2020 |
| SPD Marketplace Limited | Wholesale & retail | 2020 |
| SPD Robotics Limited | Wholesale & retail | 2020 |
| Specialist Rescue Trauma Care Ltd | Health & social care | 2024 |
| Spectra Print Limited | Manufacturing | 2026 |
| Spectra Service Solutions Limited | Professional & scientific | 2026 |
| Spilt Milk Studios Ltd | Information & communication | 2010 |
| SPM (Brighton) Limited | Real estate | 2024 |
| SPM (Folkestone) Limited | Real estate | 2024 |
| SPR138 Ltd | Manufacturing | 2019 |
| Spray Chrome Solutions Ltd. | Manufacturing | 2012 |
| Spring a. M. Ltd | Administrative & support | 2007 |
| Springer Homes Property Services Limited | Households | 2024 |
| Springer Homes Thanet Limited | Real estate | 2017 |
| Springlane Apartments Ltd | Real estate | 2021 |
| Squareone IT Ltd | Information & communication | 2026 |
| Ssar Properties Ltd | Real estate | 2025 |
| SSM Freehold Limited | Households | 2011 |
| ST Crispins Close Management Limited | Households | 2020 |
| ST Marys Chapel Bar Ltd | Hospitality | 2024 |
| ST Mildreds Group Ltd | Real estate | 2024 |
| ST Peters Freehold Limited | Real estate | 2010 |
| ST Peters RTM Company Limited | Extraterritorial | 2024 |
| ST Peters Sausage Company Ltd | Extraterritorial | 2020 |
| ST. Crispins Ltd. | Construction | 1984 |
| ST. Cuby Management Company Limited | Households | 1999 |
| Stafford Contracting Limited | Construction | 2023 |
| Stak Marine Ltd | Professional & scientific | 2016 |
| Starc Properties Limited | Real estate | 2025 |
| Steinau Two Limited | Information & communication | 2022 |
| Sterling E-Commerce Ltd | Wholesale & retail | 2026 |
| Steve Slark Consultancy Ltd | Water & waste | 2013 |
| Steven 8 Marine Limited | Extraterritorial | 2013 |
| Stillwater Rock Limited | Information & communication | 2016 |
| Stokes & SON Contractors Limited | Construction | 2009 |
| Stokes Construction Ltd | Construction | 2018 |
| Stonar Developments Limited | Construction | 1996 |
| Stone Bay Consultancy Ltd | Professional & scientific | 2023 |
| Stone Farm Freehold Ltd | Extraterritorial | 2020 |
| Stone VFX Limited | Information & communication | 2024 |
| Stourbay Developments Limited | Construction | 2014 |
| Stranger Solutions Limited | Professional & scientific | 2018 |
| Stranglx Ltd | Construction | 2022 |
| Strategic Land Planning Solutions Limited | Professional & scientific | 2014 |
| Streeter & Co Ltd | Wholesale & retail | 2020 |
| Stroud Windows (Kent) Limited | Construction | 2020 |
| Strutsen Ltd | Construction | 2022 |
| Sttm WWX Limited | Other services | 2023 |
| Studio OAC Limited | Information & communication | 2023 |
| Studio Proviso Ltd | Professional & scientific | 2023 |
| Studio Spranks Ltd | Professional & scientific | 2018 |