| Executive Transitions Limited | Education | 2011 |
| Executive XL Ltd | Transport & logistics | 2025 |
| Exelto Limited | Information & communication | 2021 |
| Exeqline Transfers Ltd | Transport & logistics | 2026 |
| Exertus Electrical Services Limited | Construction | 2018 |
| Exeter Air Conditioning Ltd | Energy | 2025 |
| Exhale Systems Limited | Manufacturing | 2025 |
| Exhibition Systems Limited | Manufacturing | 1989 |
| Exhibitions and Displays Direct Ltd. | Administrative & support | 1999 |
| Exige Infrastructure Management Limited | Administrative & support | 2016 |
| Exile PDR Ltd | Wholesale & retail | 2023 |
| Existem Events Limited | Administrative & support | 2008 |
| Existem Ltd | Administrative & support | 2003 |
| Exit Child Events CIC | Health & social care | 2025 |
| Exit Through the Gift Shop Limited | Professional & scientific | 2013 |
| EXO Recruit Ltd | Administrative & support | 2025 |
| EXO Recruitment Ltd | Administrative & support | 2023 |
| Exoffice Ltd | Administrative & support | 2025 |
| Exoplanit Ltd | Information & communication | 2017 |
| Exotherm Products Limited | Manufacturing | 1983 |
| EXP World UK Limited | Real estate | 2019 |
| Expand Building Limited | Construction | 2012 |
| Expanse Surveys Ltd | Information & communication | 2017 |
| Expansion Education Ltd | Education | 2024 |
| Expansion Joint Services Limited | Construction | 2010 |
| EXPD8 FM Limited | Extraterritorial | 2009 |
| EXPD8 Limited | Professional & scientific | 2002 |
| EXPD8 UK Limited | Extraterritorial | 2009 |
| Expedia Group Holdings UK Limited | Financial services | 2024 |
| Expedia Treasury Services Limited | Administrative & support | 2017 |
| Expedia Treasury UK Holdings Limited | Financial services | 2024 |
| Expedient AI Ltd | Wholesale & retail | 2026 |
| Expedite Ltd | Information & communication | 2007 |
| Expedition Company Limited | Arts & recreation | 2010 |
| Expeditious Lettings Ltd | Real estate | 2021 |
| Expensys Limited | Information & communication | 2011 |
| Experientia Consulting Services Ltd | Professional & scientific | 2018 |
| Expert Medical Solutions Ltd | Health & social care | 2026 |
| Expert Mortgages Ltd | Extraterritorial | 2015 |
| Expert Self Care Ltd | Information & communication | 2012 |
| Expert SK Limited | Transport & logistics | 2026 |
| Expert TEN Limited | Professional & scientific | 2005 |
| Expertsinn Ltd | Professional & scientific | 2026 |
| Explaining Science Publishing Ltd | Information & communication | 2026 |
| Expleo Technology UK Limited | Information & communication | 1999 |
| Explore With Hayley Ltd | Administrative & support | 2025 |
| Exploreacity Limited | Administrative & support | 2019 |
| Explorer Dome Limited | Education | 2017 |
| Exponent AI Ltd | Information & communication | 2024 |
| Exponential IP Ltd | Administrative & support | 2024 |
| Exporter PAL Limited | Wholesale & retail | 2018 |
| Exposure Education Ltd | Education | 2025 |
| Exposure Marketing Ltd | Administrative & support | 2026 |
| Exposure MEN Studio Ltd | Other services | 2018 |
| Expotex Limited | Professional & scientific | 2025 |
| Express Agency Ltd | Administrative & support | 2020 |
| Express Box Delivery Limited | Transport & logistics | 2025 |
| Express Classes Ltd | Arts & recreation | 2019 |
| Express Cutters Limited | Manufacturing | 1997 |
| Express Delivery Limited | Wholesale & retail | 2025 |
| Express Electrics Site Services Limited | Wholesale & retail | 1988 |
| Express Graphic Supplies Ltd | Wholesale & retail | 2019 |
| Express Mailing & Shipping Ltd | Transport & logistics | 2025 |
| Express Pizza & Grill Ltd | Hospitality | 2025 |
| Express Scaffolding (South West) Limited | Construction | 2020 |
| Express Shoe Repairs Limited | Wholesale & retail | 2015 |
| Express Signs (Bristol) Ltd | Arts & recreation | 2006 |
| Express Slice Ltd | Hospitality | 2020 |
| Express Visas Services Limited | Professional & scientific | 2016 |
| Expressions of Glory Ltd | Other services | 2012 |
| Expressions Swindon Limited | Wholesale & retail | 2012 |
| Exquis Apps Ltd | Professional & scientific | 2022 |
| Exquisite Car Care Limited | Professional & scientific | 2012 |
| Exquisite Integrated Ltd | Health & social care | 2023 |
| Exquisite Limited | Arts & recreation | 2024 |
| Exscitor Property Development Limited | Real estate | 2026 |
| Exsell Property Solutions Limited | Real estate | 2025 |
| Exsell Sales & Marketing Limited | Administrative & support | 2002 |
| Exstotech Limited | Information & communication | 2011 |
| Extend Limited | Construction | 2024 |
| Extinction Games Ltd | Information & communication | 2023 |
| Extra Mile Motors Ltd | Wholesale & retail | 2021 |
| Extra Technology Limited | Information & communication | 2007 |
| Extracellular Holdings Ltd | Financial services | 2025 |
| Extracellular Ltd | Professional & scientific | 2022 |
| Extract Coffee Roasters Ltd | Manufacturing | 2007 |
| Extraordinary Homes Ltd | Real estate | 2021 |
| Extreamuk Ltd | Other services | 2020 |
| Extreme Challenges and Adventures Ltd | Arts & recreation | 2014 |
| Extreme Circuitry Ltd | Professional & scientific | 2007 |
| Extreme Classrooms Ltd | Education | 2014 |
| Extreme Clean (Bristol) Ltd | Administrative & support | 2016 |
| Extreme Coatings Ltd | Construction | 2026 |
| Extreme Drilling Ltd | Construction | 2009 |
| Extreme Kleen Forensic Ltd | Administrative & support | 2026 |
| Extreme Marine (SW) Ltd | Arts & recreation | 2003 |
| Exworks Limited | Construction | 1998 |
| Exylon Ltd | Information & communication | 2018 |
| EYD Ltd | Manufacturing | 2015 |
| EYE FLY Limited | Information & communication | 2023 |