| En&Co Ltd | Wholesale & retail | 2026 |
| Enable (Marketing & Promotions) Ltd | Administrative & support | 2003 |
| Enable Development Ltd | Extraterritorial | 2023 |
| Enable EP Services Ltd | Education | 2025 |
| Enable EU Recruitment Ltd | Administrative & support | 2023 |
| Enable Power Design Ltd | Information & communication | 2021 |
| Enable Promotional Marketing Limited | Administrative & support | 2014 |
| Enable Sales Recruitment Ltd | Administrative & support | 2016 |
| Enable US Recruitment Ltd | Administrative & support | 2023 |
| Enact Consultants Ltd. | Professional & scientific | 2016 |
| Enamel Academy Ltd | Education | 2026 |
| Enautodetailing Ltd | Administrative & support | 2025 |
| Encana (U.K.) Holdings Limited | Professional & scientific | 2003 |
| Encelade LP | | 2015 |
| Encender Ltd | Professional & scientific | 2017 |
| Enchanted Balloons Bristol Limited | Wholesale & retail | 2013 |
| Enchanted Scents Ltd | Wholesale & retail | 2025 |
| Enclai Ltd | Information & communication | 2026 |
| Enco Services Limited | Wholesale & retail | 1984 |
| Encom FM Ltd | Administrative & support | 2021 |
| Encom Group Ltd | Wholesale & retail | 2025 |
| Encom Shelf Limited | Administrative & support | 2024 |
| Encore Building and Decorating Services Ltd | Construction | 2018 |
| Encore Engineering Ltd | Professional & scientific | 2023 |
| Encore Media Group Ltd | Administrative & support | 2020 |
| Encore Theatre Group Ltd | Arts & recreation | 2025 |
| Encosta Holdings Limited | Real estate | 2001 |
| Encounter Walking Holidays Limited | Administrative & support | 2012 |
| Encounters Festivals Ltd | Information & communication | 1996 |
| Encura Ltd | Manufacturing | 2018 |
| END Point Events Ltd | Professional & scientific | 2026 |
| END With Your SAY Ltd | Wholesale & retail | 2026 |
| Endaxi Ltd | Professional & scientific | 2026 |
| Endearment Education Consultancy Ltd | Education | 2024 |
| Endeavor Engineering Solutions Ltd | Professional & scientific | 2013 |
| Endeavour Band Ltd | Wholesale & retail | 2024 |
| Endgame Labs Ltd | Professional & scientific | 2026 |
| Endless Summer Campers Ltd | Administrative & support | 2018 |
| Endless Waves Ltd | Arts & recreation | 2026 |
| Endo Land Ltd | Health & social care | 2024 |
| Endocrine Health Limited | Health & social care | 2014 |
| Endometriosistests.Com Limited | Health & social care | 2025 |
| Endoro LP | | 2016 |
| Endurock Consulting Ltd | Professional & scientific | 2017 |
| Enea Software (UK) Ltd. | Information & communication | 2000 |
| Eneff Consultancy Limited | Financial services | 2007 |
| Enelar Limited | Financial services | 2003 |
| Enelyst Ltd | Professional & scientific | 2025 |
| Enemuoh Eco Cleaning Services Ltd | Extraterritorial | 2023 |
| Enemy Lines Films Limited | Information & communication | 2018 |
| Enemy Mindz International CIC | Health & social care | 2021 |
| Enemy Mindz Ltd | Education | 2020 |
| Energetic Bristol Limited | Extraterritorial | 2011 |
| Energetiq Ltd | Professional & scientific | 2025 |
| Energimise Ltd | Information & communication | 2023 |
| Energise Health Ltd | Health & social care | 2019 |
| Energised Performance UK Limited | Health & social care | 2011 |
| Energisehr Ltd | Administrative & support | 2023 |
| Energize Health and Fitness Centre Limited | Arts & recreation | 2006 |
| Energy and Environmental Technology Ltd | Professional & scientific | 2013 |
| Energy and Technical Services Limited | Professional & scientific | 2005 |
| Energy Approach Ltd | Professional & scientific | 2025 |
| Energy Assessment Associates Limited | Professional & scientific | 2009 |
| Energy Bright Ltd | Professional & scientific | 2026 |
| Energy Control Solutions (South West) Limited | Construction | 2011 |
| Energy Control Solutions Limited | Construction | 2012 |
| Energy Efficiency Initiatives Ltd | Professional & scientific | 2026 |
| Energy for Life Unlimited Limited | Education | 2025 |
| Energy Management Controls Ltd | Professional & scientific | 2015 |
| Energy Service Bristol Limited | Extraterritorial | 2020 |
| Energy Solutions (South West) Ltd | Manufacturing | 2018 |
| Energy System Design Ltd | Professional & scientific | 2023 |
| Energy Volunteers CIC | Professional & scientific | 2023 |
| Energycon Ltd | Administrative & support | 2003 |
| Enex Civils Limited | Construction | 2025 |
| Enforcement Response Limited | Professional & scientific | 1993 |
| Enfortitude Ltd | Real estate | 2021 |
| ENG Bauen Limited | Administrative & support | 2017 |
| Eng-Mac Ltd | Professional & scientific | 2024 |
| Engage Architecture Ltd | Professional & scientific | 2012 |
| Engage Software Limited | Information & communication | 2010 |
| Engaged-It Ltd | Information & communication | 2018 |
| Engagingpotential Limited | Health & social care | 2008 |
| Engai Ltd | Information & communication | 2026 |
| Engds Ltd | Professional & scientific | 2011 |
| Engelhart BV Ltd | Other services | 2023 |
| Engels Protechnic Ltd | Manufacturing | 1994 |
| Engine House (Bristol) Ltd | Households | 2020 |
| Engine House Developments Limited | Real estate | 2017 |
| Engine House Marketing Ltd | Professional & scientific | 2025 |
| Engine House Property Ltd | Real estate | 2019 |
| Engine House Solutions Ltd | Information & communication | 2015 |
| Engine Room (SW) Ltd | Arts & recreation | 2023 |
| Enginecomm Ltd | Professional & scientific | 2022 |
| ENGINEER89 Ltd | Information & communication | 2023 |
| Engineered Vibration Solutions Ltd | Construction | 2020 |
| Engineering Edge Limited | Professional & scientific | 2017 |
| Engineering IS Easy Ltd | Information & communication | 2024 |
| Engineering Maintenance Systems Ltd | Professional & scientific | 1999 |
| Engineering Programme Management Solutions Ltd | Professional & scientific | 2019 |