| Bristol Reclaimed Timber & Furniture Ltd | Manufacturing | 2024 |
| Bristol Recovery Ltd | Extraterritorial | 2022 |
| Bristol Recruitment Limited | Administrative & support | 2026 |
| Bristol Recycling Limited | Water & waste | 2022 |
| Bristol Red Lion PUB Co Limited | Hospitality | 2011 |
| Bristol Refugee Festival CIC | Education | 2017 |
| Bristol Refugee Rights | Other services | 2006 |
| Bristol Refurbishment Ltd | Construction | 2023 |
| Bristol Render Solutions Ltd | Construction | 2022 |
| Bristol Rendering Limited | Construction | 2024 |
| Bristol Rendering Specialists Ltd | Construction | 2019 |
| Bristol Renewable Heat Ltd | Construction | 2023 |
| Bristol Renewables Ltd | Construction | 2024 |
| Bristol Renovations Ltd | Construction | 2016 |
| Bristol Reptile Emporium Ltd | Wholesale & retail | 2015 |
| Bristol Reptile Encounters Ltd | Arts & recreation | 2022 |
| Bristol Resin Company Ltd | Construction | 2024 |
| Bristol Resolution Limited | Professional & scientific | 2013 |
| Bristol Resource Ltd | Administrative & support | 2022 |
| Bristol Restaurant Group Ltd | Hospitality | 2021 |
| Bristol Ringside ABC Limited | Education | 2024 |
| Bristol Risk Solutions Limited | Professional & scientific | 2020 |
| Bristol Road Hand Car Wash Ltd | Other services | 2022 |
| Bristol Road HCW Ltd | Wholesale & retail | 2025 |
| Bristol Robotics Laboratory Limited | Extraterritorial | 2019 |
| Bristol Robotics Limited | Extraterritorial | 2019 |
| Bristol Rock Centre Ltd | Education | 2011 |
| Bristol Rocks Limited | Arts & recreation | 2011 |
| Bristol Rocks Tavern Limited | Hospitality | 2014 |
| Bristol Roofing & Maintenance Limited | Construction | 2024 |
| Bristol Roofing Ltd | Construction | 2014 |
| Bristol Roofing Solutions Ltd | Construction | 2013 |
| Bristol Roofing Specialists Ltd | Construction | 2025 |
| Bristol Roofs Limited | Construction | 2024 |
| Bristol Rooms Ltd | Real estate | 2018 |
| Bristol Rope & Twine Co. Ltd | Wholesale & retail | 2013 |
| Bristol Rose Commercial Limited | Financial services | 2025 |
| Bristol Rose Mortgages Ltd | Financial services | 2024 |
| Bristol Rovers (1883) Limited | Arts & recreation | 2002 |
| Bristol Rovers Community Trust | Education | 2001 |
| Bristol Rugby Club Limited | Arts & recreation | 1998 |
| Bristol Rugby Community Foundation | Arts & recreation | 2010 |
| Bristol Rugs Ltd | Wholesale & retail | 2023 |
| Bristol Safes and Security Cabinets Limited | Wholesale & retail | 2010 |
| Bristol Safety Deposit Limited | Wholesale & retail | 2025 |
| Bristol Sanctuary Theatre CIC | Arts & recreation | 2025 |
| Bristol Saracens Rugby Football Club Limited | Arts & recreation | 2012 |
| Bristol Sarafi Ltd | Construction | 2017 |
| Bristol Sash Window Company Limited | Construction | 2013 |
| Bristol Sash Window Services Ltd | Construction | 2020 |
| Bristol Sauna Collective Limited | Other services | 2025 |
| Bristol School of Acting Ltd | Education | 2021 |
| Bristol School of Art Media and Design Limited | Extraterritorial | 2004 |
| Bristol School of Performing Arts - "Dare to Dream" (Asas) Limited | Arts & recreation | 2020 |
| Bristol School of Performing Arts Limited | Arts & recreation | 2004 |
| Bristol School of Shiatsu Limited | Education | 2021 |
| Bristol School of Yoga Limited | Education | 2011 |
| Bristol Scrap Metal Ltd | Wholesale & retail | 2010 |
| Bristol Security and Property Management Limited | Administrative & support | 1983 |
| Bristol Security Systems Limited | Construction | 2008 |
| Bristol SEM Limited | Health & social care | 2017 |
| Bristol Shared Ltd | Real estate | 2020 |
| Bristol Sheds & Gates Ltd | Construction | 2025 |
| Bristol Shipbrokers Ltd | Transport & logistics | 2021 |
| Bristol Shopmobility | Other services | 1991 |
| Bristol Shopping Ltd | Wholesale & retail | 2025 |
| Bristol Shoulder Specialists Limited | Health & social care | 2011 |
| Bristol Site Engineering Services Limited | Professional & scientific | 2020 |
| Bristol Skin Cancer Limited | Health & social care | 2019 |
| Bristol Skin Clinic Limited | Other services | 2022 |
| Bristol Sky Park Limited | Transport & logistics | 2018 |
| Bristol Smash Burger Private Limited | Hospitality | 2025 |
| Bristol Somali Forum CIC | Administrative & support | 2025 |
| Bristol Somali Link Ltd | Professional & scientific | 2025 |
| Bristol Somali Resource Centre | Information & communication | 2008 |
| Bristol Sound and Lighting Limited | Administrative & support | 2015 |
| Bristol Sound Proofing Limited | Construction | 2016 |
| Bristol Sound Systems Limited | Wholesale & retail | 1963 |
| Bristol Soundproofing Products Limited | Wholesale & retail | 2022 |
| Bristol South Build Group Ltd | Construction | 2026 |
| Bristol South Decorating Limited | Construction | 2019 |
| Bristol Specialised Gynecological Services Limited | Health & social care | 2019 |
| Bristol Spirits Limited | Wholesale & retail | 1993 |
| Bristol Spoke Co Ltd. | Wholesale & retail | 2019 |
| Bristol Sport Limited | Arts & recreation | 2011 |
| Bristol ST Andrews Bowling Club Limited | Arts & recreation | 1924 |
| Bristol Starter Comps Ltd | Arts & recreation | 2025 |
| Bristol Storage Equipment Limited | Construction | 1971 |
| Bristol Stretch Tents Ltd | Administrative & support | 2021 |
| Bristol Student Accommodation Ltd | Extraterritorial | 2026 |
| Bristol Student Lets Ltd | Real estate | 2013 |
| Bristol Style Collective Limited | Other services | 2016 |
| Bristol Surgical Air Ltd | Manufacturing | 2013 |
| Bristol Surveying Company Ltd | Professional & scientific | 2014 |
| Bristol Surveyors Ltd | Administrative & support | 2020 |
| Bristol Sweet Mart Limited | Wholesale & retail | 2013 |
| Bristol Symphony Orchestra Limited | Arts & recreation | 2015 |
| Bristol Syrup Company Limited | Extraterritorial | 2016 |
| Bristol Table Pool Ltd | Wholesale & retail | 2025 |
| Bristol Tailoring Ltd | Other services | 2022 |