| Easy Tours Worldwide Limited | Administrative & support | 2025 |
| ED Taylor Limited | Other services | 2012 |
| Edge Racing Performance Limited | Wholesale & retail | 2024 |
| EDN Leisure Ltd | Wholesale & retail | 2016 |
| Edutainers Limited | Education | 2019 |
| Edward & Co (Brighouse) Limited | Other services | 2012 |
| Edwards Management Services Limited | Financial services | 2017 |
| EJP Precision Engineering Ltd | Professional & scientific | 2021 |
| Ejpp Developments Ltd | Construction | 2024 |
| EJW1988 Ltd | Hospitality | 2025 |
| Elani Hair Ltd | Other services | 2023 |
| Electra Commercial Vehicles Ltd | Manufacturing | 2017 |
| Electric Kisses Ltd | Other services | 2025 |
| Electriserve Electrical Contractors Ltd | Construction | 2022 |
| Elegant Homes Construction Limited | Construction | 2021 |
| Elementary Digital (Holdings) Ltd | Financial services | 2023 |
| Elementary Digital Limited | Information & communication | 2013 |
| Elementary IT Ltd | Information & communication | 2022 |
| Eliona Consulting Ltd | Construction | 2024 |
| Elite Level Support Ltd | Education | 2025 |
| Elland Car Sales Ltd | Wholesale & retail | 2015 |
| Elland Road Car Sales Limited | Wholesale & retail | 2019 |
| Elliott Plant Hire Ltd | Construction | 1993 |
| Ellis Lloyd Associates Limited | Administrative & support | 2016 |
| Elms Engineering Ltd | Professional & scientific | 2023 |
| Eludeactivewear Ltd | Wholesale & retail | 2023 |
| Elysian Beauty Ltd | Other services | 2019 |
| Elysian Hair Ltd | Other services | 2019 |
| Elysian Salon Limited | Other services | 2022 |
| Emaculate Investments Ltd | Real estate | 2025 |
| Emerald Doors Limited | Wholesale & retail | 2007 |
| Empire Hair Limited | Other services | 2016 |
| EMU North Ltd | Information & communication | 2025 |
| Endo (IT) Ltd | Information & communication | 2022 |
| Endo (UK) Consultancy Ltd | Information & communication | 2018 |
| Endo (UK) Ltd | Professional & scientific | 2014 |
| Endo (UK) Medical Resources Limited | Professional & scientific | 2018 |
| Endo (UK) Recruitment Ltd | Administrative & support | 2018 |
| Endo UK (EX Military Recruitment) Ltd | Professional & scientific | 2018 |
| Engineering in Motion Limited | Professional & scientific | 2007 |
| Enventure Research Limited | Professional & scientific | 2003 |
| Envira Floor Limited | Construction | 2021 |
| Enviraclad Ltd | Construction | 2014 |
| Enviratiles Ltd | Construction | 2024 |
| Erudex Ltd | Construction | 2015 |
| Esml Ltd | Wholesale & retail | 2023 |
| Essential Compliance Training Ltd | Professional & scientific | 2021 |
| Euro-Star Foods Limited | Wholesale & retail | 1994 |
| Eurostar Commodities Limited | Wholesale & retail | 1996 |
| EVA Evangelou Ltd | Education | 2021 |
| Every Step Smarter Ltd | Health & social care | 2025 |
| Evolve Software Consulting Limited | Information & communication | 2017 |
| Evolve Specialist Cars Ltd | Wholesale & retail | 2019 |
| Expect Distribution Holdings Limited | Financial services | 2021 |
| Expect Warehousing Limited | Extraterritorial | 2005 |
| Expedite Law Limited | Information & communication | 2022 |
| Exploria Ltd | Wholesale & retail | 2011 |
| Express Catering Supplies Limited | Manufacturing | 2000 |
| Express Dairies Limited | Wholesale & retail | 2021 |
| External Doors Online Ltd | Administrative & support | 2021 |
| EY UP Properties Ltd | Real estate | 2025 |
| EYE SPY Brands Limited | Administrative & support | 2011 |
| F. O'Malley & Sons Limited | Construction | 1976 |
| Fastsell Ltd | Wholesale & retail | 2024 |
| FCH Ltd | Financial services | 2025 |
| Fearnley Rhodes Limited | Financial services | 2012 |
| Feathers Halifax Ltd | Hospitality | 2015 |
| Feet Street Kids Ltd | Wholesale & retail | 2019 |
| Felicity Recruitment Service Limited | Administrative & support | 2023 |
| Fentrack Limited | Information & communication | 2017 |
| Fernando Trading Limited | Construction | 2019 |
| Finesse Jewellers Limited | Wholesale & retail | 2014 |
| Fire SEC Data Fire & Security Limited | Construction | 2019 |
| Firesec Integrated Solutions Limited | Construction | 2026 |
| First to Finish Limited | Manufacturing | 2023 |
| Firth Profiles IP Limited | Administrative & support | 2019 |
| Firth Steels Limited | Manufacturing | 1983 |
| Flappit Tipping and Recycling Limited | Water & waste | 2013 |
| Floodland Limited | Real estate | 2016 |
| Flow Group Services Midco Ltd | Financial services | 2026 |
| Flow-States-App Ltd | Information & communication | 2026 |
| Food 4 Thought Catering Limited | Wholesale & retail | 2008 |
| Foodiez (HD) Ltd | Hospitality | 2025 |
| Fork in the Fish Limited | Hospitality | 2021 |
| Fortis Personal Training Ltd | Arts & recreation | 2026 |
| Foulds Clark (London) Limited | Manufacturing | 1968 |
| Foundations Property Group Ltd | Financial services | 2024 |
| Foycol Limited | Wholesale & retail | 2007 |
| Fozen Limited | Information & communication | 2018 |
| Fozzys Autocentre Ltd | Wholesale & retail | 2021 |
| Frank Platt Electrical Limited | Real estate | 1972 |
| Frederick Crowther & SON Limited | Manufacturing | 1955 |
| Freeman Assets Limited | Agriculture & fishing | 2019 |
| Front Foot HR Consultancy Ltd | Administrative & support | 2025 |
| Fronttech Ltd | Information & communication | 2022 |
| FSB Property Ltd | Real estate | 2025 |
| Fsmh Group Limited | Transport & logistics | 2024 |
| Full Circle Property Partners Ltd | Real estate | 2020 |
| Fusion IT Management Limited | Information & communication | 2003 |
| Fuso Truck UK Limited | Wholesale & retail | 2026 |