| Smashed Events Ltd | Arts & recreation | 2016 |
| Sober Butterfly CIC | Health & social care | 2024 |
| Social Folk Coffee Limited | Hospitality | 2024 |
| Sooper Limited | Information & communication | 2022 |
| Soul Spirit Restoration Ltd | Health & social care | 2024 |
| Sovereign Lubricants (UK) Limited | Wholesale & retail | 1980 |
| Sovereign Lubricants (Yorkshire) Limited | Real estate | 1995 |
| Space-Build Limited | Manufacturing | 1996 |
| Spacechanger Ltd | Construction | 2021 |
| Spares Plus Ltd | Wholesale & retail | 2020 |
| Spark Energy UK Ltd | Information & communication | 2022 |
| Spectrum Comms (Solutions) Limited | Information & communication | 2020 |
| Spice 138 Ltd | Hospitality | 2023 |
| Spiderninja Limited | Information & communication | 2017 |
| SPM Management Limited | Wholesale & retail | 2013 |
| ST John's (CE) Primary Academy Trust, Clifton | Education | 2011 |
| ST Pegs Logistics Limited | Wholesale & retail | 2012 |
| Stanico Employment Limited | Professional & scientific | 2007 |
| Stark Industry Ents Ltd | Extraterritorial | 2025 |
| Staytied Ltd | Wholesale & retail | 2025 |
| Steele Works Property Ltd | Real estate | 2026 |
| Steeples Financial Services Limited | Financial services | 2017 |
| Stem Racing Limited | Professional & scientific | 2002 |
| Stepaway Limited | Real estate | 2001 |
| Stercap Nurseries Ltd. | Education | 2011 |
| Steve O'Reilly Limited | Construction | 2003 |
| STF Building Supplies Ltd | Wholesale & retail | 2020 |
| Stoddart Consulting Limited | Professional & scientific | 2019 |
| Stoddart Prints Limited | Wholesale & retail | 2024 |
| Stone Asset Holdings Ltd | Real estate | 2026 |
| Stone Circle and Square Mile Property Holdings Ltd | Financial services | 2025 |
| Stone Developmentsuk Ltd | Construction | 2020 |
| Stone Investment Group Ltd | Real estate | 2025 |
| Stone Leaseholds Ltd | Real estate | 2026 |
| Stone Property Holdings Ltd | Real estate | 2020 |
| Stratton Park Motors Ltd | Wholesale & retail | 2019 |
| Strom Vision Limited | Administrative & support | 2007 |
| Styling by Katie Limited | Other services | 2024 |
| Success 888 Ltd | Hospitality | 2021 |
| Sundae Social Ltd | Hospitality | 2025 |
| Sunningdale House Developments (Walmer Management Company) Limited | Households | 2017 |
| Suppremacy Ltd | Wholesale & retail | 2024 |
| Swadish Indian Restaurant & Takeaway Ltd | Hospitality | 2024 |
| Swifty Software Ltd | Information & communication | 2021 |
| Swimrite Leisure Limited | Arts & recreation | 1999 |
| Sykes and Price Limited | Real estate | 2022 |
| SYN Enterprises Ltd | Hospitality | 2024 |
| Szep Limited | Health & social care | 2019 |
| T & R Motors Limited | Wholesale & retail | 2017 |
| T G Building Services Ltd | Construction | 2020 |
| T Mortgage Solutions Ltd | Financial services | 2019 |
| T-Shirt & Vape Ltd | Wholesale & retail | 2025 |
| Tafs Products Ltd | Manufacturing | 2014 |
| Take Flight Bird Control Limited | Professional & scientific | 2004 |
| Talismann Property Limited | Real estate | 2018 |
| Tamabo Ltd | Health & social care | 2018 |
| Taylor Fabrications Group Ltd | Manufacturing | 2024 |
| TCW Access Ltd | Administrative & support | 2026 |
| TEN Barbers Limited | Other services | 2025 |
| Tennant Investments Limited | Real estate | 2004 |
| Terraseal Limited | Construction | 2017 |
| Terry the Carpet Fitter Ltd | Construction | 2004 |
| TEZ TEZ Painting & Decorating Ltd | Construction | 2025 |
| THE Avocet Hardware Group Limited | Wholesale & retail | 2017 |
| THE Barge-Brighouse Ltd | Hospitality | 2025 |
| THE BB Furniture Group Limited | Wholesale & retail | 2023 |
| THE Black Horse Inn Clifton Limited | Hospitality | 2020 |
| THE Brick Yard (Brighouse) Ltd | Hospitality | 2023 |
| THE Bridal Studio at Roberttown Limited | Wholesale & retail | 2015 |
| THE Carpet Tile Centre Limited | Wholesale & retail | 2012 |
| THE Crafty FOX Ltd | Hospitality | 2019 |
| THE Croissant Shop Limited | Wholesale & retail | 2017 |
| THE Crow Bar & Kitchen Ltd | Hospitality | 2018 |
| THE Dart Vault Ltd | Wholesale & retail | 2024 |
| THE Dhruva Tara Ltd | Wholesale & retail | 2025 |
| THE Digital Organisation Ltd. | Professional & scientific | 2019 |
| THE Finance Geek Ltd | Financial services | 2019 |
| THE Financial Partnership Advisers Limited | Financial services | 2009 |
| THE Fire Protection Group Holdings Ltd | Financial services | 2026 |
| THE Flower Garden (Brighouse) Ltd | Wholesale & retail | 2025 |
| THE Flower School Ltd | Wholesale & retail | 2021 |
| THE Good Karma Collective Limited | Manufacturing | 2023 |
| THE HOP Yard Limited | Hospitality | 2024 |
| THE Hound Ville (Yorkshire) Limited | Other services | 2023 |
| THE Hound Ville Limited | Other services | 2019 |
| THE Hourglass Bar Limited | Hospitality | 2021 |
| THE Joy Collection Limited | Wholesale & retail | 2024 |
| THE Leeds Psychology Practice Limited | Health & social care | 2021 |
| THE Marshall Organisation Ltd | Information & communication | 2019 |
| THE Nest Yorkshire Ltd | Health & social care | 2026 |
| THE Old Ship Inn (Brighouse) Ltd | Hospitality | 2025 |
| THE PAW DEN Limited | Other services | 2025 |
| THE Plumbing People NW Ltd | Construction | 2011 |
| THE Print Portal Ltd | Manufacturing | 2019 |
| THE Prom DEN Ltd | Wholesale & retail | 2022 |
| THE Turntable Vinyl Cafe Ltd | Wholesale & retail | 2019 |
| THE Twisted Tree BAG Collection Ltd | Manufacturing | 2026 |
| THE UK Agency Limited | Wholesale & retail | 2018 |
| THE Vault Bar (Brighouse) Ltd | Hospitality | 2025 |
| THE Willows Day Nursery (Brighouse) Ltd | Health & social care | 2016 |