| D & T Riggall Jewellers (Brigg) Ltd | Wholesale & retail | 2018 |
| D C Chatterton Limited | Other services | 2004 |
| D Hughes Landscaping Ltd | Professional & scientific | 2025 |
| D Thompson Plumbing & Heating Ltd | Construction | 2024 |
| D. Jacklin Limited | Agriculture & fishing | 2004 |
| D1 Projects Ltd | Construction | 2025 |
| Damian Limited | Wholesale & retail | 2005 |
| DAN Albone and SON Limited | Agriculture & fishing | 1955 |
| DAN Rowson Agriculture Limited | Agriculture & fishing | 2017 |
| Daniel Delatouche Ltd | Health & social care | 2021 |
| David Jenkins Meats (Grimsby) Limited | Wholesale & retail | 2018 |
| David Mcnicholas Golf Ltd | Arts & recreation | 2011 |
| Dc-Fit Ltd | Health & social care | 2019 |
| Dcbean Technical Sales Limited | Wholesale & retail | 2026 |
| Dckc Properties Limited | Real estate | 2019 |
| DDM Agriculture (Bawtry) Limited | Administrative & support | 2018 |
| DDM Agriculture (Howden) Limited | Administrative & support | 2023 |
| DDM Agriculture Limited | Administrative & support | 1999 |
| DDM Trustees Limited | Other services | 2024 |
| Dean Wray Carpets Limited | Construction | 2002 |
| Dean Wray Rentals Limited | Real estate | 2025 |
| Dedicated Courier Ltd | Transport & logistics | 2025 |
| Delta Construction Hull Limited | Construction | 2011 |
| Demeter (Brigg) Limited | Professional & scientific | 2024 |
| Dents of Brigg Limited | Wholesale & retail | 2002 |
| Derwent Properties (Yorkshire) Ltd | Real estate | 2021 |
| Dewstone Consultants Limited | Professional & scientific | 1995 |
| DH Architecture Limited | Professional & scientific | 2018 |
| Diyar Pizza Ltd | Hospitality | 2020 |
| DJ Smith Engineering Services Ltd | Construction | 2023 |
| DLM Air Solutions Limited | Energy | 2011 |
| DN37 Properties Ltd | Real estate | 2021 |
| Docks Digital Limited | Professional & scientific | 2019 |
| Double Sided Limited | Professional & scientific | 2004 |
| Dowse Haulage Limited | Transport & logistics | 2003 |
| DR LJ Ltd | Education | 2018 |
| Dunham's Bakery Ltd | Manufacturing | 2020 |
| Dunscroft Properties Limited | Construction | 2016 |
| Durable Systems Ltd | Real estate | 2013 |
| DVM Contractors Ltd | Construction | 2025 |
| E&I Design Solutions Ltd | Professional & scientific | 2021 |
| E&I Engineering Limited | Professional & scientific | 2019 |
| East Damp Solutions Ltd | Construction | 2025 |
| East Yorkshire Engineering Ltd | Construction | 2018 |
| Eastcoast Aggregates Ltd | Other services | 2024 |
| Eazi Storage Ltd | Transport & logistics | 2020 |
| Eco Friendly Online Ltd | Wholesale & retail | 2026 |
| Edparts Ltd | Wholesale & retail | 2021 |
| Edward Albone Limited | Agriculture & fishing | 1979 |
| Edwark Design & Engineering Ltd | Administrative & support | 2022 |
| ELJ Residential Ltd | Real estate | 2022 |
| ELM House Software Ltd | Information & communication | 1999 |
| Elmm Coaching Limited | Professional & scientific | 2014 |
| Elsham Garage Services Limited | Wholesale & retail | 2000 |
| Elsham Hall Limited | Hospitality | 2024 |
| Elsham Hall Services Ltd | Hospitality | 2024 |
| EMC Testing Services Ltd | Professional & scientific | 2023 |
| Empower Diversity Ltd | Administrative & support | 2024 |
| Empower Hauls Ltd | Water & waste | 2025 |
| Engineering Management Intelligence Limited | Professional & scientific | 2026 |
| Equability Limited | Professional & scientific | 2009 |
| Ethical Pepper Limited | Wholesale & retail | 2021 |
| Event Hire by Cooks Ltd | Administrative & support | 2024 |
| Everett Investments | Real estate | 1950 |
| EWE Holdings Limited | Financial services | 2022 |
| Ewol Ltd | Wholesale & retail | 2025 |
| F Turnbull Limited | Other services | 2009 |
| Faribi Services Ltd | Health & social care | 2018 |
| Farnsworth Consulting Ltd | Professional & scientific | 2023 |
| Felixstowe Land Train Limited | Arts & recreation | 2018 |
| Fellowes and Sons Limited | Administrative & support | 2022 |
| Femme B Beauty Ltd | Wholesale & retail | 2021 |
| Fennswood Ltd | Arts & recreation | 2020 |
| Fentonghyll Limited | Real estate | 1993 |
| Fenwicks Tree and Garden Care Limited | Agriculture & fishing | 2024 |
| Festino (Finance) Limited | Administrative & support | 1973 |
| Financial Planning Associates LLP | | 2011 |
| Finch Farms Ltd | Agriculture & fishing | 2016 |
| Firbrook (Agriculture) Limited | Transport & logistics | 1983 |
| Firbrook Holdings Limited | Real estate | 2013 |
| First Choice Cladding Limited | Construction | 2023 |
| First Phase Sports Limited | Professional & scientific | 2026 |
| FL Capital Limited | Financial services | 2021 |
| Forrester Hall Garage Management Company Limited | Administrative & support | 2015 |
| Franklin and SON Farming Limited | Agriculture & fishing | 1996 |
| Franks Curtis Limited | Extraterritorial | 2012 |
| Freedom Roofline Design Limited | Construction | 2010 |
| Freeman (Fish Merchants) Limited | Wholesale & retail | 2009 |
| Freerange Software (UK) Limited | Other services | 1998 |
| FSH Pubs Limited | Hospitality | 2026 |
| Funforest Limited | Arts & recreation | 2006 |
| G & J Rentals Ltd | Real estate | 2025 |
| G H C Investments Limited | Real estate | 2019 |
| G Plastering Ltd | Construction | 2021 |
| G-Arrl Group LLP | | 2025 |
| G.O.C. International Limited | Agriculture & fishing | 2006 |
| Gaia Workplace Wellbeing Ltd | Health & social care | 2022 |
| Gainsborough Rope Access Limited | Construction | 2024 |
| Gary Johnson Racing Ltd | Arts & recreation | 2016 |
| GB Plant Services Limited | Construction | 2019 |