| DR Sophie Fletcher Limited | Education | 2025 |
| Dreadnought Developments Holdings Limited | Real estate | 2019 |
| Dreadnought Developments Limited | Real estate | 2019 |
| Dream Developers ( Cornwall ) Limited | Other services | 2016 |
| Dreamsider Ltd | Wholesale & retail | 2018 |
| Drive on Motors Ltd | Wholesale & retail | 2024 |
| Driving Force Media Limited | Information & communication | 2008 |
| DRM Refurbishments Ltd | Construction | 2019 |
| Droitwich Spa Nursing & Residential Home Limited | Professional & scientific | 1985 |
| DS Brookes Ltd | Manufacturing | 1998 |
| Dsns Consultancy Limited | Professional & scientific | 2023 |
| Ductwork Installation Solutions Limited | Construction | 2020 |
| Dudley Building Services Ltd | Construction | 2022 |
| Dudley Car Repair Ltd | Wholesale & retail | 2026 |
| Dudley Council for Voluntary Service | Health & social care | 1986 |
| Dudley CVS Enterprises Limited | Hospitality | 2015 |
| Dudley DPF Solutions Ltd | Wholesale & retail | 2025 |
| Dudley FC Ltd | Hospitality | 2026 |
| Dudley Federation of Tenant and Residents Association | Households | 2002 |
| Dudley Motor Services Limited | Wholesale & retail | 2016 |
| Dudley New Touch Barbers Ltd | Other services | 2021 |
| Dudley Town Football Club Limited | Arts & recreation | 2017 |
| Dunhampton Park Holdings Ltd | Financial services | 2025 |
| Dunhampton Park Ltd | Real estate | 2025 |
| Dunkley Descents Ltd | Construction | 2025 |
| Dunkley Properties Limited | Real estate | 2013 |
| Dustair Limited | Manufacturing | 1968 |
| Dusty Recesses Ltd | Professional & scientific | 2024 |
| DVH Investigations and Consultancy Ltd | Administrative & support | 2022 |
| Dvnci Ltd | Manufacturing | 2024 |
| DY Brockmoor Limited | Hospitality | 2022 |
| DY Fashion Limited | Wholesale & retail | 2025 |
| DY5 Cuts Ltd | Other services | 2026 |
| DY5 Motors Ltd | Wholesale & retail | 2019 |
| DY5 Orange Shop Ltd | Wholesale & retail | 2026 |
| DY8 Desinz Ltd | Other services | 2012 |
| Dyson & Sons Limited | Wholesale & retail | 2005 |
| Dyson Products Limited | Wholesale & retail | 1946 |
| E & S Accessories Limited | Wholesale & retail | 2005 |
| E-Finity Limited | Wholesale & retail | 2025 |
| E.G.J.S Properties Limited | Real estate | 2024 |
| E.Marsh Upholsterers Limited | Manufacturing | 2021 |
| Early Years 2 Private Day Nursery Limited | Health & social care | 2011 |
| Easiflo Fabrications Limited | Manufacturing | 1965 |
| Easiflo Investments Limited | Professional & scientific | 1962 |
| East India Trading Company Ltd | Manufacturing | 2025 |
| Eastfield Recycling Limited | Water & waste | 2015 |
| Eaton-Williams Holdings Limited | Manufacturing | 1994 |
| Eatvendmens Ltd | Administrative & support | 2017 |
| Ebmp Properties Limited | Real estate | 2021 |
| EC22 Properties Limited | Real estate | 2023 |
| ECC Design and Engineering UK Ltd | Professional & scientific | 2021 |
| Echelon Lift Services Limited | Construction | 2024 |
| Echo Housing Group Ltd | Real estate | 2022 |
| Ecology Associates Ltd | Professional & scientific | 2021 |
| Ecoswift Couriers Ltd | Transport & logistics | 2025 |
| Ecotik Delivery & Logistics Limited | Transport & logistics | 2023 |
| ECS Equestrian Group Limited | Agriculture & fishing | 2025 |
| EDA Civil Engineering Limited | Construction | 2018 |
| Eddips Holdings Limited | Financial services | 2019 |
| Eden Design Contracts Ltd | Construction | 2017 |
| Eden Park Property Investments Limited | Real estate | 2020 |
| Educ@T Ltd | Education | 2024 |
| Edwardstone Properties Limited | Real estate | 2025 |
| Egjs Holdings Limited | Wholesale & retail | 2023 |
| EIGHTY3 Design Ltd | Information & communication | 2015 |
| Eitilt Limited | Financial services | 2023 |
| EJB Security Limited | Financial services | 2025 |
| EL7 Properties Limited | Real estate | 2021 |
| Electrical Skills Training Ltd | Education | 2018 |
| Electriciannearmemidlands Ltd | Construction | 2025 |
| Electromotive Technologies Ltd | Transport & logistics | 2019 |
| Electrotechnology Limited | Manufacturing | 2008 |
| Elegant (Worcestershire) Limited | Construction | 2012 |
| Elegant Developments Limited | Other services | 2005 |
| Elegant Dickens Heath (Village Sales) Limited | Construction | 2018 |
| Elegant Hampton Green Limited | Construction | 2018 |
| Elegant Homes (Hampton in Arden) Limited | Construction | 2011 |
| Elevate Asset & Commercial Finance Ltd | Information & communication | 2023 |
| Elise Design Services Limited | Professional & scientific | 2019 |
| Elite Builders Slough Limited | Construction | 2020 |
| Elite Engraving by M&S Limited | Professional & scientific | 2024 |
| Elite Glass & Glazing Ltd | Manufacturing | 2007 |
| Elite Motor-Tech Ltd | Professional & scientific | 2012 |
| Elite Removals & Export Limited | Other services | 2021 |
| Elitecart Ltd | Wholesale & retail | 2024 |
| Elpeberl Ltd | Construction | 2016 |
| ELS (Midlands) Limited | Professional & scientific | 2019 |
| Elura Aesthetics Limited | Other services | 2026 |
| ELV Recycling (Midlands) Limited | Water & waste | 2006 |
| ELY Spedition Limited | Transport & logistics | 2026 |
| Embeth Property Limited | Real estate | 2020 |
| Embracing Relocation Ltd | Real estate | 2019 |
| Emedia SEO Limited | Professional & scientific | 2023 |
| EMH Building Contractors Ltd | Construction | 2024 |
| Emiris Ltd | Administrative & support | 2017 |
| Emmiera Group Ltd | Other services | 2004 |
| Empire Recovery Ltd | Wholesale & retail | 2021 |
| Empire Support Services Ltd | Administrative & support | 2016 |
| Empowersphere Ltd | Professional & scientific | 2025 |