| Drainforce UK Ltd | Administrative & support | 2012 |
| Draintech Surveys Limited | Construction | 2007 |
| Draybond Limited | Information & communication | 2024 |
| Draymoss Limited | Extraterritorial | 2025 |
| Drayreed Limited | Extraterritorial | 2025 |
| Drewgunn Properties Ltd | Real estate | 2021 |
| Drinks Inn Co Ltd | Hospitality | 2023 |
| Drive TV Ltd | Information & communication | 2002 |
| Driveshaft Services (Holdings) Limited | Professional & scientific | 2015 |
| Driveshaft Services Limited | Manufacturing | 1998 |
| Drone Training Ltd | Education | 2014 |
| Drudwy Group Limited | Financial services | 2021 |
| DRY Wall Systems (Bridgend) Limited | Construction | 2000 |
| DS Pumping Stations Ltd | Professional & scientific | 2007 |
| Dsar Consultancy Ltd | Wholesale & retail | 2025 |
| DSE Electrical Group Ltd | Construction | 2025 |
| Dsear and Atex Limited | Professional & scientific | 2023 |
| DSL Building Services Limited | Construction | 2018 |
| DSL Houses Ltd | Real estate | 2024 |
| DST Innovations Limited | Manufacturing | 2011 |
| DTH Building & Landscaping Ltd | Construction | 2024 |
| Duffryn Oaks Management Limited | Real estate | 2004 |
| Duman Bookkeeping Ltd | Professional & scientific | 2021 |
| Dunes Care Limited | Health & social care | 2018 |
| Dunraven Holdings Limited | Manufacturing | 2007 |
| Dunraven Windows Retail Limited | Wholesale & retail | 2000 |
| Dunrite Roofing and Building Limited | Construction | 2026 |
| Durabunker Limited | Construction | 2014 |
| Durston's Coffee Ltd | Manufacturing | 2014 |
| Duru IT Repairs & Web Desing Services Ltd | Professional & scientific | 2019 |
| Dust & Go Cleaners Ltd | Administrative & support | 2023 |
| DV Property Limited | Real estate | 2015 |
| DW Stroud Ltd | Professional & scientific | 2018 |
| DWA Accountants Limited | Professional & scientific | 2022 |
| DWA Limited | Professional & scientific | 2022 |
| Dwep Ltd | Manufacturing | 2014 |
| DWT (Enterprises) Limited | Hospitality | 1992 |
| DYA Logistics Limited | Transport & logistics | 2017 |
| Dyfrig Hopkin Limited | Wholesale & retail | 2007 |
| Dylaspice Ltd | Hospitality | 2025 |
| Dynamic Supplements Limited | Wholesale & retail | 2025 |
| E & M Automotive Limited | Wholesale & retail | 2025 |
| E C Management Consulting Ltd | Professional & scientific | 2019 |
| E&G Senior Care Limited | Health & social care | 2016 |
| E-Bane Ltd | Administrative & support | 2022 |
| E-Dma Consulting Ltd | Professional & scientific | 2025 |
| E. T. Clay Products Limited | Wholesale & retail | 1997 |
| E. Thomas & Sons LLP | | 2006 |
| E.G.W. Consultants Limited | Information & communication | 2016 |
| E.T. & S. Construction Limited | Construction | 1996 |
| Eager Beaver Bath Resurfacing Expert Ltd | Other services | 2024 |
| Eagle Tyres Pyle Ltd | Wholesale & retail | 2023 |
| Earth People Limited | Manufacturing | 2024 |
| Earth's Future Club Limited | Administrative & support | 2022 |
| EAS Aerospace Ltd | Wholesale & retail | 2025 |
| EAS Engineering Services Ltd | Manufacturing | 2025 |
| EAS Rentals Ltd | Administrative & support | 2025 |
| Eastform Limited | Extraterritorial | 2026 |
| Eastlake Garage Limited | Wholesale & retail | 2019 |
| Easy Auto Lease Ltd | Administrative & support | 2023 |
| Easy Care Products Ltd | Health & social care | 2023 |
| Easydoors UK Ltd | Construction | 2019 |
| EAT ME OUT Ltd | Hospitality | 2025 |
| EBA Consultancy Services Ltd | Information & communication | 2012 |
| Ebay Trading Limited | Extraterritorial | 2004 |
| Echomain Limited | Extraterritorial | 2025 |
| Eco Complete Solutions Wales Ltd | Health & social care | 2025 |
| Eco Removal Limited | Water & waste | 2020 |
| Econotherm (UK) Limited | Manufacturing | 2007 |
| Edan Healthcare Ltd | Health & social care | 2022 |
| Edenlas Limited | Energy | 2022 |
| EDGE21 Studio Ltd | Information & communication | 2020 |
| Edgebray Limited | Wholesale & retail | 2024 |
| Edgehall Limited | Extraterritorial | 2026 |
| Edgemain Limited | Extraterritorial | 2026 |
| EDI Logistics Limited | Transport & logistics | 2017 |
| Eduscriptive Ltd | Information & communication | 2025 |
| Edward Homes Ltd | Wholesale & retail | 2019 |
| Edwards Farm Services Limited | Agriculture & fishing | 2013 |
| Edwards Hire Ltd | Administrative & support | 2014 |
| Edwards Machinery Ltd | Wholesale & retail | 2008 |
| Edwards Steel Services Limited | Manufacturing | 2002 |
| Eeco MEP Ltd | Construction | 2023 |
| EG FBA Ltd | Wholesale & retail | 2024 |
| Eg&Ed Property Co. Ltd | Real estate | 2025 |
| Eglur Consulting Limited | Professional & scientific | 2024 |
| Eidurtri Ltd | Arts & recreation | 2024 |
| Eithen Place Ltd | Administrative & support | 2017 |
| EKA Clothes Ltd | Wholesale & retail | 2018 |
| Elanbond Limited | Construction | 2025 |
| Elanview Limited | Extraterritorial | 2025 |
| Elderblake Limited | Real estate | 2020 |
| Electrical & Mechanical Design Services Limited | Professional & scientific | 1995 |
| Elegance Hair Extensions by EM Ltd | Other services | 2025 |
| Elegance Hair Extensions Ltd | Wholesale & retail | 2025 |
| Elements Salon ST Brides Ltd | Other services | 2024 |
| Eleos Accountants Limited | Professional & scientific | 2023 |
| Elephant Garden Education Ltd | Education | 2020 |
| Elete Design Limited | Real estate | 1971 |
| Elevare Consulting Group Limited | Professional & scientific | 2025 |