| David C Hughes Carpentry Ltd | Manufacturing | 2024 |
| David Mews Ltd | Real estate | 2025 |
| David Taylor Advisory Services Ltd | Professional & scientific | 2025 |
| Davis James Investments Ltd | Wholesale & retail | 2024 |
| Davmerry Limited | Extraterritorial | 1988 |
| Dawes Road Limited | Households | 2021 |
| Dawnlea Enterprises Limited | Information & communication | 1997 |
| Day Liddell Limited | Hospitality | 2013 |
| Dazie Mazie's Limited | Other services | 2015 |
| DB Legal Services Limited | Professional & scientific | 2021 |
| DBG Recruitment Ltd | Administrative & support | 2023 |
| DCM Commercial and Residential Services Ltd | Construction | 2024 |
| DD Consultancy (Waste) Ltd | Professional & scientific | 2025 |
| DDN Property Limited | Real estate | 2017 |
| DDP Partners Limited | Financial services | 2025 |
| DE Beers International Ltd | Professional & scientific | 2016 |
| DE Cartel Limited | Manufacturing | 2025 |
| DE Luca Hair & Beauty Ltd | Other services | 2012 |
| DE Trafford Estates Churchgate Block J Limited | Administrative & support | 2015 |
| DE Vere Pharma Ltd | Wholesale & retail | 2022 |
| De'Milia Properties Ltd | Real estate | 2023 |
| De'Milia Travel Ltd | Administrative & support | 2024 |
| Dean Heating Ltd | Other services | 2021 |
| Dean Tucker Ltd | Administrative & support | 2014 |
| Debenham Homes Limited | Construction | 1992 |
| Debt Recovery & Enforcement Ltd | Administrative & support | 2024 |
| DEC the Tree Ltd | Other services | 2022 |
| Decent Audio Ltd | Manufacturing | 2023 |
| Decent Ventures Limited | Real estate | 2020 |
| Decimal Place Advisory Limited | Professional & scientific | 2018 |
| Deckanon Ltd | Construction | 2002 |
| Dedikated PR Ltd | Professional & scientific | 2018 |
| Deeba London Limited | Wholesale & retail | 2018 |
| Deep Analytics Ltd | Information & communication | 2017 |
| Deepshi IT Solutions Limited | Information & communication | 2015 |
| Defence Security Solutions Company Limited | Administrative & support | 2015 |
| Defined Clinic Ltd | Other services | 2023 |
| Degree of Darkness Ltd | Wholesale & retail | 2020 |
| Dehughes Limited | Energy | 2014 |
| Deidson Services Ltd | Construction | 2015 |
| Deighan Perkins LLP | | 2009 |
| DEL Maci Limited | Administrative & support | 2023 |
| Delemere Ventures Limited | Administrative & support | 2017 |
| Delimores Limited | Hospitality | 2011 |
| Delnevo Refurbishments Ltd | Construction | 2023 |
| Delon Developments Ltd | Construction | 2026 |
| Delta Legal Search Ltd | Administrative & support | 2025 |
| Deltech Sheet Metal Limited | Manufacturing | 2014 |
| Deluxe Meats Limited | Wholesale & retail | 2006 |
| Demand GEN Matters Ltd | Professional & scientific | 2024 |
| Demoney Management Limited | Real estate | 2009 |
| Demoney Projects Limited | Households | 2020 |
| Denia Consultancy Services Limited | Professional & scientific | 2016 |
| Denim Solutions Limited | Manufacturing | 2013 |
| Dennehy Construction Limited | Construction | 2005 |
| Denola Homes Limited | Real estate | 2022 |
| Densmiles Limited | Health & social care | 2025 |
| Denzal Holding Ltd | Financial services | 2016 |
| Depe Services Ltd | Professional & scientific | 2024 |
| Derivatives in Fund Management Limited | Administrative & support | 2005 |
| Derma Aesthetics Clinic Ltd | Health & social care | 2013 |
| Dermatox Ltd | Administrative & support | 2023 |
| Derw Gwyn Ltd | Real estate | 2025 |
| DES Safe Security and Electrical Ltd. | Administrative & support | 2019 |
| Design & Build Foundations Ltd | Construction | 2018 |
| Design by Flight Limited | Professional & scientific | 2018 |
| Design by TOI Limited | Manufacturing | 2023 |
| Designg (London) Limited | Administrative & support | 2008 |
| Designsixtyfour Limited | Professional & scientific | 2012 |
| Deskaway Limited | Real estate | 2025 |
| Destination Education Limited | Administrative & support | 2008 |
| Destiny Ltd | Real estate | 2021 |
| Detrafford (MBJ) Limited | Administrative & support | 2016 |
| Detrafford (ZMS) Limited | Administrative & support | 2016 |
| DEV Shree Krishna Limited | Wholesale & retail | 2026 |
| Devalis Limited | Other services | 2023 |
| Devaney Interiors Limited | Construction | 2024 |
| Develop Warwickshire (Nominee) Limited | Construction | 2022 |
| Devineuk Ltd | Information & communication | 2024 |
| Devonshire House Skin Clinic Limited | Other services | 2019 |
| Devonshire House Surgery Limited | Health & social care | 2007 |
| Dewberry Holdings Ltd | Financial services | 2022 |
| DF Sports Management Limited | Administrative & support | 2014 |
| DF2020 Limited | Information & communication | 2014 |
| DG Infotech Ltd | Information & communication | 2014 |
| DGL Distribution Ltd | Wholesale & retail | 2022 |
| Dham Consulting Ltd | Professional & scientific | 2024 |
| Dhane Properties Ltd | Construction | 2016 |
| DHN Enterprises Ltd | Other services | 2019 |
| Dhol Academy Ltd | Extraterritorial | 2019 |
| Diamond Capital Group Ltd | Real estate | 2023 |
| Diamond Cleanings and Properties Limited | Wholesale & retail | 2025 |
| Diamond Developments Phase 1 Limited | Construction | 2019 |
| Diamond Developments Phase 2 Ltd | Construction | 2023 |
| Diamond Driving School Ltd | Education | 2011 |
| Diamond Fire Solutions Ltd | Construction | 2019 |
| Diamond Heart Homes Limited | Administrative & support | 2025 |
| Diamond Rocket Trading Ltd | Financial services | 2013 |
| Digging Badger Limited | Professional & scientific | 2010 |
| Digiform Ltd | Professional & scientific | 2021 |