| Sado Engineers Limited | Manufacturing | 2014 |
| Saeed Bridal Gallery Ltd | Wholesale & retail | 2019 |
| SAF Accounting & Business Services Limited | Professional & scientific | 2016 |
| SAF Builders (BFD) Ltd | Construction | 2019 |
| Saf.M Ltd | Other services | 2020 |
| Safa Islamic Store Limited | Wholesale & retail | 2023 |
| Safa Lifestyle Limited | Wholesale & retail | 2026 |
| Safa Wholesale Ltd | Wholesale & retail | 2025 |
| Safar Tours Ltd | Administrative & support | 2019 |
| Safaz Express Ltd | Transport & logistics | 2019 |
| Safe Box Self Storage Ltd | Real estate | 2021 |
| Safe Electrics Contractors Ltd | Administrative & support | 2017 |
| Safe Glaze Limited | Manufacturing | 2021 |
| Safe Guard Windows Ltd | Construction | 2021 |
| Safe Harbour Care & Support Ltd | Health & social care | 2026 |
| Safe Home Heating Ltd | Professional & scientific | 2014 |
| Safe Homes (Yorkshire) CIC | Real estate | 2023 |
| Safe House Plumbing Ltd | Other services | 2017 |
| Safe Realty Ltd | Real estate | 2022 |
| Safe Renovations Ltd | Construction | 2025 |
| Safe Schools Global Ltd | Public administration | 2018 |
| Safe Search INT Ltd | Administrative & support | 2019 |
| Safe Spark Electrical Limited | Manufacturing | 2013 |
| Safe Style Properties Ltd | Real estate | 2020 |
| Safe Support Care Ltd | Health & social care | 2021 |
| Safe Travel BFD Ltd | Transport & logistics | 2025 |
| SAFE2SHIPGOODS Ltd | Wholesale & retail | 2025 |
| Safeguard Commercial Protection Limited | Administrative & support | 2022 |
| Safehands Services Limited | Health & social care | 1994 |
| Safehands Solution (Management) Limited | Other services | 2013 |
| Safely Accessible Ltd | Health & social care | 2025 |
| Safer Bound Limited | Administrative & support | 2020 |
| Safer Property Group Ltd | Real estate | 2018 |
| Saferoute Taxi Ltd | Transport & logistics | 2025 |
| Safety First Community Training Centre Limited | Education | 2008 |
| Safeway (Overseas) Limited | Wholesale & retail | 1924 |
| Safeway Carz Ltd | Transport & logistics | 2026 |
| Safeway Development Limited | Professional & scientific | 1982 |
| Safeway Food Stores Limited | Administrative & support | 1954 |
| Safeway Limited | Wholesale & retail | 1977 |
| Safeway Pension Trustees Limited | Financial services | 1977 |
| Safeway Pensions Trustees Company Limited | Professional & scientific | 1981 |
| Safeway Properties Limited | Administrative & support | 1938 |
| Safeway Quest Trustees Limited | Administrative & support | 1998 |
| Safeway Stores (Ireland) Limited | Wholesale & retail | 1997 |
| Safeway Stores Limited | Wholesale & retail | 1963 |
| Safeway Trustee (Furb) Limited | Financial services | 1983 |
| Safeway Wholesale Limited | Manufacturing | 1978 |
| Saffah Investments Limited | Real estate | 2024 |
| Saffiakhanacademy Ltd | Health & social care | 2025 |
| Saffron Dean Community Association | Administrative & support | 1995 |
| Saffron Express (NE) Limited | Hospitality | 2016 |
| Saffron News Ltd | Wholesale & retail | 2026 |
| Saffron's Spice UK Ltd | Hospitality | 2019 |
| Safi Khan Foods Ltd | Wholesale & retail | 2024 |
| Safi Recycling Ltd | Wholesale & retail | 2025 |
| Safi Traders Ltd | Wholesale & retail | 2025 |
| Safronut Limited | Wholesale & retail | 2025 |
| Safsun Enterprises Limited | Professional & scientific | 2023 |
| Safwan Grewal Ltd | Wholesale & retail | 2023 |
| Sagar Joinery Projects Ltd | Construction | 2025 |
| Sage V G Limited | Professional & scientific | 2000 |
| Saghah Properties Ltd | Real estate | 2019 |
| Sagu Motors Limited | Wholesale & retail | 2009 |
| Sahabas Coffee Ltd | Manufacturing | 2019 |
| Sahabas Ltd | Extraterritorial | 2013 |
| Sahar IT Limited | Wholesale & retail | 2020 |
| Sahar Media Services Limited | Information & communication | 2016 |
| Sahar Trading Ltd | Wholesale & retail | 2025 |
| Sahara Pharmacy Ltd | Extraterritorial | 2010 |
| Sahil Haulage Services Ltd | Transport & logistics | 2019 |
| Sahil Khan Ltd | Wholesale & retail | 2025 |
| Sahp Limited | Manufacturing | 2019 |
| Saia Trading Ltd | Wholesale & retail | 2024 |
| Saidy's Security Ltd | Administrative & support | 2025 |
| Saif ALI Contracting Services Ltd | Professional & scientific | 2023 |
| Saif KS Limited | Professional & scientific | 2019 |
| Saif Linen Hire Ltd | Other services | 2012 |
| Saif Space CIC | Arts & recreation | 2022 |
| Saif Trade Sales Ltd | Wholesale & retail | 2026 |
| Saifan Ltd | Professional & scientific | 2019 |
| Saifee Medical Solutions Ltd | Wholesale & retail | 2023 |
| Sailvvay UK Ltd | Wholesale & retail | 2024 |
| Saima Aziz Limited | Wholesale & retail | 2025 |
| Saina Skin Clinic Ltd | Other services | 2025 |
| Saino Business Services Ltd | Administrative & support | 2019 |
| Saint Jude's Services Ltd | Administrative & support | 2019 |
| Saint Martin Trading Ltd | Construction | 2025 |
| Saint Simonside Ltd | Hospitality | 2016 |
| Saira Healthcare Ltd | Health & social care | 2026 |
| Sairish's Community Care Ltd | Health & social care | 2025 |
| Saivenuk Ltd | Wholesale & retail | 2025 |
| SAJ 72 Holding Co Limited | Financial services | 2026 |
| SAJ Logistic Solutions Ltd | Transport & logistics | 2026 |
| SAJ Property Corp Ltd | Real estate | 2026 |
| SAJ Property Rentals Ltd | Real estate | 2024 |
| Sajid & Arif Investments Ltd | Construction | 2021 |
| Sajid Group Limited | Financial services | 2025 |
| Sajjad Fabrications Ltd | Other services | 2024 |
| Sajn PVT Ltd | Other services | 2022 |