| Roman Hill Consultancy Ltd | Professional & scientific | 2019 |
| Romanian Beauty and Style Limited | Wholesale & retail | 2017 |
| Roofstyle (South) Limited | Construction | 2002 |
| Rooh Investment Group Ltd | Real estate | 2025 |
| Rooke Services Limited | Construction | 2020 |
| Root and Pursuit Ltd | Agriculture & fishing | 2023 |
| Rootstock & Barrel Ltd | Hospitality | 2026 |
| Rosebrook Solutions Limited | Wholesale & retail | 2015 |
| Rosedale Brickwork Contractors Limited | Construction | 1996 |
| Rosewood Design and Build Ltd | Construction | 2019 |
| Roskellycorp Ltd | Information & communication | 2021 |
| Ross HS UK Limited | Information & communication | 2008 |
| Rougz Hair & Beauty Ltd | Other services | 2014 |
| Roundabout Events Ltd | Hospitality | 2023 |
| Route Stop Limited | Wholesale & retail | 2026 |
| ROW Farm Limited | Agriculture & fishing | 2006 |
| Rowker Consultancy Ltd | Water & waste | 2023 |
| Royal County of Berkshire Transport Limited | Transport & logistics | 2021 |
| Royale Berkshire Bathrooms Ltd | Construction | 2022 |
| Royle Tiling Ltd | Construction | 2020 |
| RPP Solutions Limited | Wholesale & retail | 2009 |
| RR Communications Ltd | Information & communication | 2016 |
| RR Niruvanam Ltd | Information & communication | 2019 |
| RRT Sussex Limited | Wholesale & retail | 2026 |
| RS Carpainter Limited | Wholesale & retail | 2026 |
| RSI Mechanical Ltd | Wholesale & retail | 2019 |
| Rsjones Limited | Professional & scientific | 2018 |
| RSN Works Ltd | Manufacturing | 2025 |
| RT21 Ltd | Hospitality | 2021 |
| RTL Roman Tesliuk Logistics Ltd | Transport & logistics | 2025 |
| RTT Solutions Limited | Information & communication | 2013 |
| Rubicon 23 Limited | Administrative & support | 2023 |
| Ruby Doo's Boutique Limited | Professional & scientific | 2015 |
| Ruby IT Services Limited | Information & communication | 2005 |
| Rukay Properties Ltd | Real estate | 2024 |
| Rule PPM Limited | Professional & scientific | 2026 |
| Rusford Heating Ltd | Construction | 2018 |
| RVG Solutions Ltd | Professional & scientific | 2019 |
| Ryehurst Group Limited | Financial services | 2026 |
| Ryehurst Holdings Limited | Real estate | 2020 |
| Ryslip Group Limited (the) | Agriculture & fishing | 1963 |
| S F Repairs (Commercial) Ltd | Wholesale & retail | 2013 |
| S Ring Lighting Ltd | Information & communication | 2015 |
| S V Drishti Ltd | Extraterritorial | 2025 |
| S&V International Ltd | Extraterritorial | 2024 |
| S.A.F Electrics Ltd | Construction | 2006 |
| S.A.R. Transport Ltd | Transport & logistics | 2011 |
| S.S Retail Group Ltd | Wholesale & retail | 2024 |
| S.S.M. Developments Limited | Other services | 1979 |
| S01 Dining Ltd | Hospitality | 2026 |
| S23 Construction Limited | Construction | 2021 |
| SA Building Ltd | Construction | 2020 |
| SA IT Consulting Limited | Information & communication | 2016 |
| SA Team Ltd | Arts & recreation | 2014 |
| SAB Fitness Berkshire LLP | | 2019 |
| Sabbarton Sales Solutions Limited | Professional & scientific | 2006 |
| Sabl Sport Limited | Administrative & support | 2024 |
| Sachdev Dwellings Ltd | Real estate | 2025 |
| Sadi MA Boli Limited | Education | 2014 |
| Safari Automotive Limited | Wholesale & retail | 2025 |
| Safe Pet Crates Limited | Wholesale & retail | 2024 |
| Safe Tact Security Ltd | Other services | 2024 |
| Safe Windows and Doors Limited | Construction | 2019 |
| Safebathe Ltd | Construction | 2025 |
| Safenurture Care Ltd | Health & social care | 2025 |
| Safety AS Standard Ltd | Professional & scientific | 2005 |
| Safety Connect Ltd | Professional & scientific | 2026 |
| Saffafoods Ltd | Hospitality | 2024 |
| Saffron Food Consulting Limited | Hospitality | 2022 |
| Saftech Ltd | Information & communication | 2003 |
| Sage Equity Release Limited | Financial services | 2018 |
| Sage Projects Limited | Transport & logistics | 1990 |
| Sakup Limited | Health & social care | 2013 |
| Salcal Limited | Professional & scientific | 2019 |
| Sally Salon Services Limited | Wholesale & retail | 1972 |
| Sally UK Holdings Limited | Financial services | 2006 |
| Sally's Pipe Dream LLP | | 2026 |
| Saltway Day Nursery Ltd | Education | 2016 |
| Salty Days Limited | Professional & scientific | 2025 |
| Salwey Roofing Limited | Construction | 2017 |
| SAM Kingston Consulting Limited | Professional & scientific | 2003 |
| SAM RAO Yoga Ltd | Arts & recreation | 2003 |
| Sam's Roofing and Building Ltd | Construction | 2021 |
| Samartha Homes Ltd | Real estate | 2021 |
| Samhorizon Hub Limited | Wholesale & retail | 2024 |
| Sancronis Limited | Professional & scientific | 2017 |
| Sandford Grey Holdings Limited | Real estate | 2020 |
| Sandhurst Town Football Club Limited | Arts & recreation | 2005 |
| Sandoz Limited | Manufacturing | 1981 |
| Sandsdigitalproducts Ltd | Education | 2025 |
| Sante Global LLP | | 2020 |
| Sante Trading Group LLP | | 2026 |
| Sapire Limited | Wholesale & retail | 2025 |
| Sapna Education Limited | Health & social care | 2025 |
| Sapphire Aviation UK Limited | Transport & logistics | 2025 |
| Sapta Giri Estates Ltd | Real estate | 2026 |
| Sarah Venturi Design Ltd | Manufacturing | 2026 |
| Sarah's Angels Ltd | Health & social care | 2025 |
| SAS Business Services Limited | Professional & scientific | 2007 |
| SAS Drone Services Ltd | Agriculture & fishing | 2014 |