| Cowley Collaboration Ltd | Real estate | 2025 |
| Crackling Fayre Ltd | Hospitality | 2025 |
| Craig Cutler Plumbing and Heating Ltd | Construction | 2018 |
| Cranberry Foods Limited | Extraterritorial | 2003 |
| Cranidge Capital Ltd | Real estate | 2020 |
| CRC Construction Logistics Limited | Administrative & support | 2026 |
| CRC Contractors Ltd | Administrative & support | 2025 |
| Crest Racing Ltd | Manufacturing | 2014 |
| Crinkle Hill Limited | Real estate | 2024 |
| Crosby Composites Limited | Manufacturing | 1986 |
| Crouch Electrical Limited | Construction | 2013 |
| Crown Conservatories Windows and Doors Ltd | Construction | 2010 |
| Crown Entertainment Production Limited | Arts & recreation | 2023 |
| Crown M K Ltd | Real estate | 2019 |
| Crystal Business Solutions Ltd | Health & social care | 2016 |
| CSG Longboat Ltd | Professional & scientific | 2007 |
| Ctillco Limited | Administrative & support | 2025 |
| Curious Hearts Ltd | Education | 2026 |
| Curly Pals Ltd | Wholesale & retail | 2026 |
| Cutting Edge (Northants) Limited | Other services | 2009 |
| CVD Consulting Services Ltd | Professional & scientific | 2023 |
| Cwest Ventures Limited | Professional & scientific | 2017 |
| Cwim Consulting Ltd | Professional & scientific | 2016 |
| CWW Construction Limited | Construction | 2025 |
| Cybersmackstudios Ltd | Information & communication | 2022 |
| Cygnet Management Limited | Other services | 2017 |
| Cygnet Ventures Limited | Real estate | 2017 |
| D C N Professional Services Ltd | Transport & logistics | 2021 |
| D C Robinson Ltd | Wholesale & retail | 2019 |
| D James Construction Limited | Construction | 2017 |
| D L C Painting Services Limited | Construction | 2012 |
| D M Tiling Brackley Ltd | Construction | 2014 |
| D&A Testing Solutions Ltd | Wholesale & retail | 2016 |
| Dace Group Limited | Financial services | 2015 |
| Daffurn Plaster Works Limited | Construction | 2012 |
| DAG Enginnering Limited | Manufacturing | 2024 |
| Daintree Services Ltd | Transport & logistics | 2026 |
| Dakota Business Services Ltd | Administrative & support | 2024 |
| Dale Plumbing and Heating Ltd | Construction | 2022 |
| DANNY86 Ltd | Transport & logistics | 2023 |
| Dauntless U/W Limited | Financial services | 2026 |
| Dave Keenan Plumbing & Heating Limited | Construction | 2012 |
| David Barnett Farms Limited | Agriculture & fishing | 1960 |
| Davisgt Engineering Ltd | Manufacturing | 2022 |
| DC Windows & Doors Roofline Ltd | Construction | 2025 |
| Dcat Hotels & Restaurant Limited | Hospitality | 2024 |
| DE Boer & Schardijn Ltd | Extraterritorial | 2006 |
| DE Felipe Derma Limited | Real estate | 2019 |
| Deans Events Limited | Wholesale & retail | 2013 |
| Decorum Care Homes Limited | Health & social care | 2024 |
| Decorum Housing Limited | Real estate | 2020 |
| Deezul Limited | Information & communication | 2010 |
| Defern Beauty Salon Ltd | Other services | 2014 |
| Deip Limited | Professional & scientific | 2016 |
| Delaplex Ltd | Information & communication | 2017 |
| Delthorne Limited | Wholesale & retail | 2018 |
| Denzils Limited | Hospitality | 2012 |
| Destinationdez Ltd | Arts & recreation | 2025 |
| Destiny Pole Ltd | Arts & recreation | 2021 |
| Detailed Training Academy Ltd | Education | 2024 |
| Devcon Four Ltd | Professional & scientific | 2012 |
| Devon Pet Food Holdings Limited | Financial services | 2024 |
| Devon Pet Food Limited | Manufacturing | 2024 |
| Digibase Ltd | Professional & scientific | 2020 |
| Digirami Software Ltd | Information & communication | 2009 |
| Digital Correlation Ltd | Information & communication | 2022 |
| Dinobyte Ltd | Information & communication | 2023 |
| Direct Access Consulting Limited | Administrative & support | 2002 |
| Distinguished Windows Ltd | Construction | 2013 |
| Dlinexsign Ltd | Manufacturing | 1984 |
| DM Gibb 42BRO Ltd | Real estate | 2025 |
| DM Gibb Holdings Ltd | Real estate | 2019 |
| DMJ Estates Ltd | Real estate | 2025 |
| DMT Tiling Ltd | Construction | 2026 |
| DNA Steak Ltd | Hospitality | 2024 |
| Domarcho Ltd | Wholesale & retail | 2025 |
| Dom’S Pizza Limited | Hospitality | 2025 |
| Dong Cuisine Limited | Hospitality | 2026 |
| DP Tech Consulting Ltd | Professional & scientific | 2025 |
| DR Sahir Shaikh Ltd | Administrative & support | 2024 |
| DRAG2ZERO Limited | Professional & scientific | 2007 |
| Drain Doctor Limited | Construction | 1993 |
| Drawn Sky Ltd | Transport & logistics | 2018 |
| Dream Doors Holdings Limited | Financial services | 2017 |
| Dream Doors Ltd | Construction | 2000 |
| DSG Mortgages Ltd | Financial services | 2017 |
| DTC International Limited | Information & communication | 2004 |
| DTC Telecom Holdings Limited | Professional & scientific | 2014 |
| Dtgr Composites Ltd | Manufacturing | 2026 |
| Duffield Contracting Limited | Administrative & support | 2017 |
| Dura Limited | Wholesale & retail | 1997 |
| DWE Scientific Limited | Administrative & support | 2016 |
| Dwyer (UK Franchising) Limited | Administrative & support | 2012 |
| Dwyer Drain Doctor Limited | Professional & scientific | 1994 |
| E & Y Best Buys Ltd | Wholesale & retail | 2012 |
| E-Comms Consulting Ltd | Information & communication | 2006 |
| E8T Limited | Administrative & support | 2020 |
| Eager Draught Limited | Wholesale & retail | 2024 |
| Eager UK Limited | Information & communication | 2006 |
| EAP Aviation Ltd | Professional & scientific | 2026 |