| Emea Technology Ltd | Wholesale & retail | 2019 |
| Emerald Builders Ltd | Construction | 2020 |
| Emerald Care Home Ltd | Health & social care | 2022 |
| Emerald Painters Southern Ltd | Construction | 2017 |
| Emeraldbuilderspainters Ltd | Construction | 2025 |
| Emergency Vehicle Services Ltd | Wholesale & retail | 2009 |
| Emily Court Right to Manage Company Ltd | Real estate | 2015 |
| Emily Fripp & Associates Ltd | Professional & scientific | 2009 |
| Emily Kitchener Limited | Wholesale & retail | 2025 |
| EMJ Quality Homecare (Dorset) Ltd | Health & social care | 2019 |
| EMM Flooring Limited | Wholesale & retail | 2020 |
| Emm's Plant House Ltd | Wholesale & retail | 2024 |
| Emma Court Right to Manage Company Limited | Real estate | 2011 |
| Emma Jane Collection Ltd | Extraterritorial | 2015 |
| Emma's Day Nursery Ltd | Education | 2016 |
| Emmys Care Ltd | Health & social care | 2023 |
| Emmys Healthcare Services Limited | Administrative & support | 2024 |
| Empire Car Wash Limited | Wholesale & retail | 2025 |
| Empire Lion Ltd | Professional & scientific | 2025 |
| Empire Trading Group Ltd | Wholesale & retail | 2023 |
| Employment Solutions South Limited | Administrative & support | 2003 |
| Empnéo Limited | Financial services | 2021 |
| Empower Crew Ltd | Professional & scientific | 2025 |
| Empower Flight Ltd | Professional & scientific | 2024 |
| Empower Homes Group Ltd | Financial services | 2021 |
| Empower Homes Properties Ltd | Real estate | 2021 |
| Empower Homes Sourcing Ltd | Real estate | 2021 |
| Empowered Momentum Ltd | Health & social care | 2021 |
| Emre Isil Ltd | Wholesale & retail | 2017 |
| Emunah Place Ltd | Hospitality | 2016 |
| Emzo Mobile Barbers Ltd | Other services | 2024 |
| ENC Events 'N' More Ltd | Hospitality | 2019 |
| ENCAPSUL8 Fire Protection Ltd | Construction | 2025 |
| Enchanted Gems Ltd | Wholesale & retail | 2024 |
| Encore Shows Ltd | Arts & recreation | 2024 |
| Encounter Holidays Ltd | Administrative & support | 2020 |
| Endeavour INK Limited | Arts & recreation | 2026 |
| Endlessgaming Network Ltd | Information & communication | 2022 |
| Endue Ltd | Administrative & support | 2017 |
| Endure Hybrid Training Club Ltd | Arts & recreation | 2025 |
| ENE Naturals Limited | Wholesale & retail | 2024 |
| Energeo Solutions Ltd | Professional & scientific | 2025 |
| Energise Holdings Limited | Real estate | 2022 |
| Energy Acoustics Limited | Professional & scientific | 2024 |
| Energy Advice Line Limited | Information & communication | 2006 |
| Energy Efficient Plumbing Services Limited | Construction | 2010 |
| Energy Guard Insulation Ltd | Construction | 2018 |
| Energy Network Services Ltd | Construction | 2001 |
| Enervus Ltd | Financial services | 2026 |
| Enfield Refrigeration Limited | Manufacturing | 1946 |
| Enfields Bournemouth Limited | Real estate | 2007 |
| Engineering & Surveying Services Limited | Professional & scientific | 2015 |
| England Civils Limited | Construction | 2014 |
| England's Coast Community Interest Company | Professional & scientific | 2024 |
| Enhance Building Services Limited | Construction | 2006 |
| Enhanced Capital Ltd | Financial services | 2023 |
| Enjoy Group International Ltd | Information & communication | 2025 |
| Enmove Ltd | Health & social care | 2023 |
| ENN Ltd | Wholesale & retail | 2024 |
| Enovo Accounting Limited | Professional & scientific | 2025 |
| Ensbury Gaff Limited | Hospitality | 2023 |
| Ensemble Property Services Ltd | Construction | 2022 |
| Ensor Developments Limited | Real estate | 2015 |
| Enspire Estates Ltd | Real estate | 2026 |
| Enter Events Ltd | Arts & recreation | 2016 |
| Enterprise Business Training Network Limited | Real estate | 2000 |
| Entire Flooring Limited | Construction | 2019 |
| Entity Dynamics Limited | Information & communication | 2025 |
| Entonhurst Limited | Real estate | 1988 |
| ENV23 Limited | Professional & scientific | 2015 |
| Enviroright Renewables Ltd | Construction | 2024 |
| EPC123 Ltd | Professional & scientific | 2025 |
| Epholidays Ltd | Administrative & support | 2019 |
| Epic Assets Ltd | Financial services | 2016 |
| Epic Renewables Ltd | Extraterritorial | 2025 |
| Epic Trails Travel Group Ltd | Information & communication | 2025 |
| Epic Wins UK Ltd | Wholesale & retail | 2025 |
| Epik Media Ltd | Other services | 2024 |
| EPIK89 Ltd | Construction | 2015 |
| Equilibrium Economics Ltd | Professional & scientific | 2012 |
| Equipaxxess Limited | Mining & quarrying | 2003 |
| Equity Squared Limited | Real estate | 2004 |
| ERA Capital Investments Ltd | Financial services | 2022 |
| ERA IT Consultants Ltd | Information & communication | 2018 |
| Erbetta Properties Ltd | Real estate | 2025 |
| ERG Deli Cafe Bar Ltd | Hospitality | 2025 |
| Ergonomic Office Furniture Limited | Professional & scientific | 2006 |
| Eric's Three Finger Music Limited | Information & communication | 1994 |
| Erinbank Freehold Limited | Households | 2005 |
| Erinbank Mansions Management Company Limited | Households | 1987 |
| Ernestoria Ltd | Professional & scientific | 2013 |
| ERP Attendant Ltd | Information & communication | 2024 |
| Erro Tool Company Limited | Wholesale & retail | 2006 |
| ERT Design Ltd | Professional & scientific | 2011 |
| Erudia Tours Ltd. | Professional & scientific | 2012 |
| ESA Property Acquisitions Limited | Real estate | 2023 |
| ESA Property Contracts Limited | Construction | 2020 |
| ESA Property Ltd | Real estate | 2019 |
| Esam AL Zarooni Advocates & Legal Consulting Ltd | Professional & scientific | 2024 |
| Esca Cafe Bar Ltd | Hospitality | 2024 |