| RWT Developments Limited | Construction | 2016 |
| Ryab Express Ltd | Transport & logistics | 2019 |
| Ryan Gardens Freehold Limited | Households | 2020 |
| Rydal Management Company Limited | Households | 1986 |
| Ryfbss Ltd | Information & communication | 2024 |
| Rynoproducts Ltd | Wholesale & retail | 2026 |
| S & E United Properties Ltd | Real estate | 2025 |
| S & M Properties Developments Ltd | Real estate | 2021 |
| S & S Tailoring Ltd | Other services | 2012 |
| S a Gillingham Accountancy Ltd | Professional & scientific | 2007 |
| S B Projects Limited | Manufacturing | 1990 |
| S Bodyshop Limited | Wholesale & retail | 2026 |
| S C Textiles Ltd | Wholesale & retail | 2017 |
| S Cook Garden Maintenance Limited | Administrative & support | 2022 |
| S Drake Estates Ltd | Real estate | 2026 |
| S K & J Holdings Limited | Financial services | 2014 |
| S M Dreams Car Wash Ltd | Administrative & support | 2025 |
| S M Marine Composites Ltd | Manufacturing | 2018 |
| S Miller Roofing Limited | Construction | 2009 |
| S Nissenbaum & SON Ltd | Real estate | 2019 |
| S S Shopfitting and Carpentry Limited | Construction | 2023 |
| S Szczech Group Limited | Information & communication | 2025 |
| S&A Amanah UK Ltd | Wholesale & retail | 2026 |
| S&A Locksmith Ltd | Wholesale & retail | 2025 |
| S&A Treader Ltd | Transport & logistics | 2024 |
| S&E Gardeners Ltd | Construction | 2018 |
| S&G Build Ltd | Construction | 2025 |
| S&G Harley Ltd | Education | 2019 |
| S&N Theatre Company | Arts & recreation | 2010 |
| S&P Splendid Smiles Ltd | Health & social care | 2014 |
| S&R Consultants Limited | Professional & scientific | 2024 |
| S. J. Churchill Limited | Real estate | 2002 |
| S.J.M. (Poole) Limited | Real estate | 2017 |
| S.L. Jones Ltd | Wholesale & retail | 2018 |
| S.O.B Direct Limited | Wholesale & retail | 2025 |
| S.O.G 88 Ltd | Transport & logistics | 2014 |
| S2 Clinical Solutions Limited | Health & social care | 2025 |
| S2S Recruitment Limited | Administrative & support | 2014 |
| S3 Projects Limited | Information & communication | 2023 |
| SA and P Holdings Limited | Real estate | 2017 |
| SA Training and Consultancy Ltd | Education | 2020 |
| SA Treader Ltd | Wholesale & retail | 2025 |
| Saad Afridi Ltd | Wholesale & retail | 2025 |
| Saba G Ltd | Administrative & support | 2016 |
| Sabana Burgers Limited | Hospitality | 2018 |
| Sabenza Holdings Ltd | Professional & scientific | 2021 |
| Sable Court RTM Company Limited | Households | 2025 |
| Sabon Kebab Ltd | Hospitality | 2015 |
| Sabre Paints Ltd | Wholesale & retail | 2021 |
| Sabreez Ltd. | Wholesale & retail | 2017 |
| Sacco&Co Property Group Ltd | Real estate | 2026 |
| Sachin Tech Ltd | Information & communication | 2025 |
| Saeful Fariz Trading Limited | Wholesale & retail | 2025 |
| Safari Constructions Limited | Construction | 2024 |
| Safatech Limited | Professional & scientific | 2000 |
| Safe & Sound Housing | Real estate | 2018 |
| Safe & Sound Investments Ltd | Real estate | 2000 |
| Safe and DRY Limited | Real estate | 2018 |
| Safe and Sound Childcare CIC | Health & social care | 2012 |
| Safe Jetting Limited | Other services | 2025 |
| Safe Solar Ltd | Wholesale & retail | 2019 |
| Safe Water Networks Ltd | Professional & scientific | 2025 |
| Safeguard Community Support Ltd | Extraterritorial | 2025 |
| Safehaven Support Ltd | Health & social care | 2025 |
| Safeshore Limited | Real estate | 2021 |
| Safesupport Security Ltd | Other services | 2017 |
| Safetec Protection Ltd | Public administration | 2019 |
| Safetest Ltd | Manufacturing | 2003 |
| Safety and Training Services Limited | Transport & logistics | 2004 |
| Saffron Hyderabadi Bowl Ltd | Hospitality | 2025 |
| Sage Financial Solutions Ltd | Financial services | 2025 |
| Sagewood House Limited | Health & social care | 2025 |
| Sahaana Homes Ltd | Real estate | 2025 |
| Sahara Student Services Limited | Education | 2016 |
| Sahur Ltd | Wholesale & retail | 2026 |
| Sail Point Poole Limited | Households | 2019 |
| Saint Augustines RTM Company Limited | Real estate | 2005 |
| Saint Clinic Academy Ltd | Other services | 2020 |
| Sajan Residential Ltd | Real estate | 2020 |
| Sakahna Limited | Professional & scientific | 2022 |
| Sakg Short Stays Limited | Hospitality | 2023 |
| SALAHLEH92 Ltd | Real estate | 2012 |
| Salam Development Limited | Real estate | 2024 |
| Salamed Limited | Health & social care | 2021 |
| Salammbo Limited | Wholesale & retail | 2019 |
| Sales Box Ltd | Wholesale & retail | 2022 |
| Salfal and Associates Ltd | Professional & scientific | 2016 |
| Salih Bekar Construction and Steel Works Limited | Construction | 2019 |
| Salika Ltd | Households | 2022 |
| Sally Whitlock HR Consulting Ltd | Administrative & support | 2018 |
| Salon Safe Solutions Ltd | Manufacturing | 2024 |
| Salsa Limited | Hospitality | 2001 |
| Salt Bay Accountancy Limited | Extraterritorial | 2019 |
| Saltaire Apartments Management Company Limited | Households | 2005 |
| Salter Rise Residents Association Limited | Hospitality | 1975 |
| Salterns Brokerage Limited | Extraterritorial | 1997 |
| Salterns Chandlery Limited | Other services | 1994 |
| Salterns Management 15/16 (RTM) Ltd | Real estate | 2010 |
| Salterns Marina Limited | Wholesale & retail | 1969 |
| Salterns Marina South Limited | Wholesale & retail | 2018 |