| Polyco Healthline Group Limited | Manufacturing | 2016 |
| Polyco Healthline Limited | Manufacturing | 1986 |
| Pomack Calibration & Control Limited | Professional & scientific | 2017 |
| Poplar Accountancy Limited | Professional & scientific | 2007 |
| Poplar Wealth Management Limited | Professional & scientific | 2022 |
| PPD Electrical Ltd | Construction | 2026 |
| PR Consultancy (Cambridgeshire) Ltd | Other services | 2018 |
| PR Property Management Cambridgeshire Ltd | Real estate | 2022 |
| Precise Law Limited | Professional & scientific | 2021 |
| Prep Station Ltd | Transport & logistics | 2024 |
| Presentation Guru Publishing Limited | Professional & scientific | 2016 |
| Prima Voca Ltd | Health & social care | 2022 |
| Priory Marine Limited | Manufacturing | 2015 |
| Priory Veterinary Practice Bourne Limited | Professional & scientific | 2023 |
| Pro Ground Competitions Limited | Wholesale & retail | 2026 |
| Probus Construction Limited | Construction | 2017 |
| Probus Group Limited | Construction | 2020 |
| Procare Domiciliary Services Ltd | Health & social care | 2020 |
| Process Engineering Limited | Professional & scientific | 2016 |
| Profile Lighting Ltd | Professional & scientific | 2018 |
| Profocus Limited | Real estate | 2020 |
| Proforge Limited | Manufacturing | 2019 |
| Prominent Women Organisation Community Interest Company | Other services | 2025 |
| Proper Sealants Ltd | Construction | 2025 |
| Provance Ltd | Wholesale & retail | 2022 |
| PSA Design Consultancy Limited | Professional & scientific | 2026 |
| PT Financial Ltd | Financial services | 2022 |
| Punjab Trucker Ltd | Transport & logistics | 2024 |
| Pure Horror Ltd | Wholesale & retail | 2023 |
| Pushing Envelopes Ltd | Professional & scientific | 2019 |
| QR Metals (UK) Limited | Water & waste | 2023 |
| QR Metals Limited | Water & waste | 2023 |
| Quinn&Ares Limited | Wholesale & retail | 2026 |
| R & B Blasting Limited | Administrative & support | 2002 |
| R E G Training & Development Limited | Professional & scientific | 1999 |
| R Property Developers Ltd | Construction | 2026 |
| R&V Kusina Ltd | Hospitality | 2026 |
| R. C. H. Dentserve Limited | Manufacturing | 2001 |
| R.A.B. Precision Engineering Ltd | Manufacturing | 2011 |
| RADI8 Systems Ltd | Manufacturing | 2026 |
| Radiant Solar Ltd | Information & communication | 2026 |
| Radrose Property Ltd | Real estate | 2023 |
| Railstone Properties Ltd | Real estate | 2016 |
| Railtainment Limited | Transport & logistics | 2022 |
| Rainbow Fixings Ltd | Wholesale & retail | 2013 |
| RCM Project Solutions Ltd | Professional & scientific | 2024 |
| Red Deer Property Ltd | Real estate | 2024 |
| Red House Rail Services Limited | Construction | 2024 |
| Red Kite Digital Consulting Limited | Professional & scientific | 2018 |
| Red Zebra Limited | Professional & scientific | 2009 |
| Redrock Systems Ltd | Real estate | 2024 |
| Redz Arena Limited | Arts & recreation | 2025 |
| Reeds Sonar Consultancy Ltd | Professional & scientific | 2014 |
| Reflex Aluminium Group Ltd | Construction | 2003 |
| Renu Holistic Beauty and Fitness Studios Limited | Other services | 2011 |
| Resources Today Ltd | Education | 2025 |
| Rewardspace Ltd | Information & communication | 2024 |
| Richard on Transport Ltd | Transport & logistics | 2021 |
| Richardson's Agriculture Ltd | Manufacturing | 2019 |
| Richmond Veterinary Services Ltd | Extraterritorial | 2021 |
| Right Light Ltd | Information & communication | 2023 |
| Riverglen Financial Associates Ltd | Financial services | 2022 |
| RJC Commercials Ltd | Administrative & support | 2025 |
| RJC Legacy Holdings Ltd | Financial services | 2026 |
| RJC Property Solutions Ltd | Construction | 2025 |
| RJC Property Trading Ltd | Real estate | 2026 |
| RM Detailing Bourne Ltd | Administrative & support | 2024 |
| Robinson A.C. Generators Services Limited | Manufacturing | 2013 |
| Rock School BUS CIC | Arts & recreation | 2021 |
| Rootkit Raccoons Ltd | Information & communication | 2026 |
| Rootridge Limited | Agriculture & fishing | 1986 |
| Roots and Wings Community CIC | Health & social care | 2025 |
| Ropley Information Technology Limited | Information & communication | 2008 |
| RPS Homes Limited | Real estate | 2023 |
| Rsec Limited | Information & communication | 2023 |
| RUBBER55 Limited | Manufacturing | 2012 |
| S & G Roofing & Cladding Inspection Ltd | Construction | 2024 |
| S & P Driver Services Limited | Other services | 2017 |
| S H Food Solutions Limited | Hospitality | 2025 |
| S M Roofing Contractors Limited | Construction | 2022 |
| S N Pubs Ltd | Hospitality | 2025 |
| S. G. C. Build Limited | Construction | 2011 |
| Sabina GUL & Company Ltd | Health & social care | 2019 |
| Safedon Limited | Other services | 2011 |
| Safeguard Installations Ltd | Administrative & support | 2008 |
| Sage Elephant Limited | Hospitality | 2023 |
| Saintas Homes Ltd | Other services | 2016 |
| Sal's Takeaway Ltd | Hospitality | 2025 |
| Salpack Ltd | Wholesale & retail | 2021 |
| SAM RAY Services Ltd | Manufacturing | 2024 |
| Sam's of Bourne Limited | Wholesale & retail | 2016 |
| Sandall Roofing Limited | Construction | 2009 |
| Sanderson's Multi Service Ltd | Professional & scientific | 2025 |
| Sandhusons Ltd | Wholesale & retail | 2021 |
| Sandtime Limited | Professional & scientific | 1996 |
| Sanjtech Engineering Services Limited | Professional & scientific | 2018 |
| Santos Accounting Ltd | Professional & scientific | 2022 |
| Sapsystek Limited | Information & communication | 2017 |
| Sarah Moysey Design Limited | Arts & recreation | 2014 |
| Sash Motorsport Limited | Manufacturing | 2023 |