| Strudel DOT Digital Limited | Information & communication | 2022 |
| Stryjecki Homes Ltd | Real estate | 2024 |
| Studded Petals Ltd | Wholesale & retail | 2020 |
| Student ACCOMMODATION4U Limited | Hospitality | 2012 |
| Studfield Limited | Professional & scientific | 2013 |
| Studio 137 Ltd | Manufacturing | 2018 |
| Studio 68 (UK) Limited | Extraterritorial | 2013 |
| Studio Grafique Ltd | Professional & scientific | 2024 |
| Studio Kuro Ltd | Information & communication | 2024 |
| Studio MGT Ltd | Professional & scientific | 2026 |
| Studio Moves Limited | Transport & logistics | 2005 |
| Studio Remko Limited | Information & communication | 2025 |
| Studio Sidika Limited | Professional & scientific | 2015 |
| Studio Tsim Ltd | Professional & scientific | 2026 |
| Studio Tyres Ltd | Wholesale & retail | 2022 |
| Studio Way Mini Mart Ltd | Wholesale & retail | 2026 |
| Studio Yearwood Ltd | Professional & scientific | 2024 |
| Studio Yesen Ltd | Professional & scientific | 2025 |
| Studiopatel Ltd | Professional & scientific | 2023 |
| Studiospares Europe Limited | Manufacturing | 2018 |
| STUDY4YOU Limited | Education | 2025 |
| Stuffed Foods Ltd | Manufacturing | 2022 |
| Su.Zhang Ltd | Wholesale & retail | 2020 |
| Subliminal Marketing Limited | Professional & scientific | 2019 |
| Subtech Digital Solutions Limited | Manufacturing | 2024 |
| Subxl Limited | Hospitality | 2014 |
| Sudbury Court Tenants Limited | Real estate | 1977 |
| Sude Taxi Ltd | Other services | 2015 |
| Sugarman Family Limited | Financial services | 2014 |
| Sukaina Properties Limited | Real estate | 2020 |
| Sull Property Services Ltd | Real estate | 2026 |
| Sullivan Bros. Limited | Construction | 1985 |
| Summer Air Ltd | Energy | 2022 |
| Summercleaningx Ltd | Administrative & support | 2025 |
| Summit Lodge Number 10 Limited | Construction | 2023 |
| Sunbeam Consulting Ltd | Professional & scientific | 2022 |
| Sunburned Limited | Information & communication | 2024 |
| Suncare and Support Ltd | Health & social care | 2022 |
| Sunderland Catering Limited | Hospitality | 2024 |
| Sunderland House (Handley Gardens) Resident Management Company Business Unit London Limited | Households | 2022 |
| Sunflower and Sage Interiors Limited | Professional & scientific | 2025 |
| Sungolde Healthcare Limited | Real estate | 2001 |
| Sunil Thalada Services Limited | Health & social care | 2015 |
| Sunningdale Carpets Ltd | Construction | 2007 |
| Sunningdale Financial Ltd | Financial services | 2016 |
| Sunny and Moon Limited | Wholesale & retail | 2024 |
| Sunny Land Homes Ltd | Real estate | 2026 |
| Sunnyside Media Ltd | Arts & recreation | 2024 |
| Sunset Avenue (Woodford) Maintenance Company Limited | Households | 1978 |
| Sunshades and Decking Ltd | Administrative & support | 2021 |
| Super-Premium UK Limited | Wholesale & retail | 2023 |
| Superfrac Limited | Manufacturing | 2011 |
| Superior Striker Management International Ltd | Education | 2018 |
| Supersuit Productions Ltd | Arts & recreation | 2020 |
| Supertone Marketing Limited | Public administration | 2015 |
| Superwell Services Co. Limited | Professional & scientific | 2015 |
| Supply Windows Limited | Construction | 2010 |
| Support for Humanity | Health & social care | 2024 |
| Supreme Shoe Care Limited | Wholesale & retail | 2013 |
| Supreme Steelworks Ltd | Manufacturing | 2023 |
| Sura Kalare Ltd | Wholesale & retail | 2025 |
| Surgic Vision Limited | Professional & scientific | 2016 |
| Surprise ME Limited | Information & communication | 2000 |
| Surrey Dental Limited | Health & social care | 2023 |
| Surrey Endocrinology Limited | Health & social care | 2023 |
| Surrey Smiles Ltd | Health & social care | 2020 |
| Surrey Urology Ltd | Health & social care | 2021 |
| Susan Goldsmith Limited | Professional & scientific | 2005 |
| Susanta Property Ltd | Real estate | 2016 |
| Suspiro Medical Limited | Health & social care | 2022 |
| Sussex Forest School Ltd. | Education | 2016 |
| Sussex Productions Limited | Arts & recreation | 2022 |
| Sussex Removals & Storage Ltd | Transport & logistics | 2016 |
| Suton Properties Limited | Real estate | 1990 |
| Sutton R4 Ltd | Health & social care | 2023 |
| Svoe Ltd | Construction | 2019 |
| SVP Properties Limited | Real estate | 2018 |
| SVS Consultants Limited | Professional & scientific | 2015 |
| Svtv Limited | Information & communication | 2003 |
| Swaker Yard (Apartments) Limited | Real estate | 2025 |
| Swaker Yard Limited | Real estate | 2023 |
| Swan & Stag Courts Limited | Households | 1993 |
| Swan Films Ltd | Information & communication | 2013 |
| Swan Windows & SON Limited | Construction | 2002 |
| Swanage Taxis Limited | Transport & logistics | 1985 |
| Swanson and James Limited | Professional & scientific | 2001 |
| Swashbuckle Ltd | Transport & logistics | 2018 |
| SWE Productions Limited | Arts & recreation | 2021 |
| Sweat Entertainment Ltd | Information & communication | 2018 |
| Sweat Music Group Ltd | Financial services | 2026 |
| Sweat Strategies Ltd | Professional & scientific | 2026 |
| Sweeney Entertainments Limited | Arts & recreation | 2015 |
| Sweet ME Keep ME Limited | Administrative & support | 2011 |
| Sweet Success Ventures Ltd | Hospitality | 2023 |
| Swift Telecommunications Ltd | Information & communication | 2022 |
| Swiftline Express Ltd | Transport & logistics | 2025 |
| Swish Sigma Limited | Information & communication | 2013 |
| Swishes Limited | Arts & recreation | 2025 |
| Swoop Hospitality Limited | Administrative & support | 2026 |
| Swoosh.Com Limited | Professional & scientific | 2010 |