| David Wickes Productions Limited | Information & communication | 1978 |
| Davidson Properties Group Ltd | Real estate | 2025 |
| Davidsons & Co Ltd | Professional & scientific | 2014 |
| Davmira London Ltd | Administrative & support | 2024 |
| Dawnmire Limited | Professional & scientific | 2020 |
| Dawton Group Ltd | Administrative & support | 2019 |
| Dawton Short Stay Ltd | Real estate | 2018 |
| Daybridge Investments Limited | Real estate | 2019 |
| Dayday Films LLP | | 2011 |
| Dayday Limited | Information & communication | 2012 |
| Daylight Glazing Limited | Construction | 2019 |
| DB Carr Limited | Professional & scientific | 2022 |
| DB Ceramic London Ltd | Extraterritorial | 2022 |
| DB Ceramic Ltd | Manufacturing | 2022 |
| DBM Environmental Ltd | Construction | 2021 |
| DBM Haulage Ltd | Water & waste | 2016 |
| DBO Productions Limited | Information & communication | 2012 |
| DC Construction.Name Ltd | Construction | 2016 |
| DC Plastering and Decorating Limited | Construction | 2018 |
| DC Props Ltd | Arts & recreation | 2017 |
| DC Transformation Ltd | Information & communication | 2013 |
| DC01 JC Limited | Financial services | 2024 |
| Dcds Holdings Ltd | Wholesale & retail | 2016 |
| DCL Assets Limited | Financial services | 2024 |
| DCL Contracting Services Ltd | Construction | 2014 |
| DCM Electrical Contractors Limited | Construction | 2013 |
| DCS Itech Limited | Professional & scientific | 2007 |
| DCS Universal Building Contractors Ltd | Construction | 2009 |
| DCT Facilities Management (Services) Ltd | Administrative & support | 2013 |
| DCT Facilities Management Ltd | Administrative & support | 2011 |
| DD Brothers Limited | Real estate | 2017 |
| DDT Security Ltd | Administrative & support | 2025 |
| DE Beauville Planning Consulting Ltd | Other services | 2019 |
| DE Beauvoir Court Freehold Limited | Households | 1996 |
| DE Gregoris Ltd | Construction | 2024 |
| DE Lobs Limited | Information & communication | 2016 |
| DE Maria LLP | | 2012 |
| DE Practice FH Ltd | Real estate | 2025 |
| DE Stefano Holdings Limited | Financial services | 2019 |
| Deacon Engineering Ltd | Professional & scientific | 2025 |
| Deacon Red Investments Ltd | Real estate | 2019 |
| Dean Arthur NDT Services Ltd | Professional & scientific | 2015 |
| Dean Spicksley Limited | Construction | 2016 |
| Deblon Limited | Financial services | 2025 |
| Deborah Developments INT Limited | Hospitality | 2020 |
| Decibel Songs Music Publishing (UK) Limited | Arts & recreation | 2015 |
| Decking to DIY Ltd | Construction | 2017 |
| Deckland Properties Limited | Real estate | 2000 |
| Deco Blinds London Ltd | Wholesale & retail | 2025 |
| Deco Bros Limited | Construction | 2022 |
| Decor Facilities Management Ltd | Real estate | 2013 |
| Decserve International Limited | Transport & logistics | 2021 |
| Deen Healthcare Ltd | Health & social care | 2021 |
| Deep Dive Digital Ltd | Information & communication | 2016 |
| Deep Lemon Limited | Information & communication | 2014 |
| Deer Muse Ltd | Information & communication | 2024 |
| Defence Mechanisms Limited | Professional & scientific | 2010 |
| Definite Cleaning Corporation Limited | Administrative & support | 2025 |
| Definitum Ltd | Professional & scientific | 2014 |
| Dek-Uk Ltd | Construction | 2019 |
| Delcap Asset Management Limited | Financial services | 1996 |
| Delipac Brands & Technologies Ltd | Wholesale & retail | 2015 |
| Delipac Limited | Administrative & support | 2012 |
| Deliverix Ltd | Hospitality | 2016 |
| Deliveroasts Limited | Administrative & support | 2020 |
| Dellfield Court (Luton) Limited | Households | 1976 |
| Dellugo Limited | Manufacturing | 1993 |
| Delphi Awakening Ltd | Administrative & support | 2024 |
| Delta ES Limited | Construction | 2012 |
| Delta Internet Limited | Information & communication | 2018 |
| Deltair Mechanical Services Ltd | Construction | 2019 |
| Demanka (Braintree) Limited | Administrative & support | 1998 |
| Demetriou Limited | Real estate | 2012 |
| Demi and Mason Construction Ltd | Construction | 2019 |
| DEN Tour Consulting Limited | Other services | 2014 |
| Denband Limited | Extraterritorial | 2020 |
| Denchy Limited | Financial services | 2012 |
| Denerest Limited | Professional & scientific | 2024 |
| Dennis & Dyer Boxing Academy Ltd | Education | 2019 |
| Denpharm Ltd | Other services | 2018 |
| Densante Limited | Health & social care | 2020 |
| Densea Deliveries LLP | | 2016 |
| Dentac Ltd | Education | 2013 |
| Dental Expert Witness Services Limited | Professional & scientific | 2017 |
| Dentaliving Ltd | Health & social care | 2019 |
| Dentaliving Marlow Ltd | Health & social care | 2019 |
| Dentify Limited | Health & social care | 2019 |
| Depuson Limited | Real estate | 2026 |
| Derby IDS SPV Ltd | Financial services | 2024 |
| Derby Trading Limited | Wholesale & retail | 2016 |
| Dermafaye Ltd | Health & social care | 2024 |
| Derrin Brothers Properties Limited | Professional & scientific | 1959 |
| Desando S.A.G. Limited | Health & social care | 2025 |
| Design a Building Ltd | Professional & scientific | 2011 |
| Design Develop Ltd | Professional & scientific | 2022 |
| Design Nomad Ltd | Other services | 2015 |
| Design Plus Build Ltd | Construction | 2019 |
| Design Skills Limited | Professional & scientific | 2018 |
| DESIGN&BUILD4UK Ltd | Construction | 2017 |
| Designed by Carr Ltd | Professional & scientific | 2022 |