| Saxon Academic Arts Ltd | Construction | 2022 |
| SBS Farming Limited | Agriculture & fishing | 2023 |
| Scadaun Consulting Ltd | Professional & scientific | 2014 |
| Scent of Salvation Ltd | Hospitality | 2020 |
| Scorpion Publishing Group Limited | Professional & scientific | 2000 |
| Scott Charles Construction Ltd | Real estate | 2023 |
| Scott Charles Design & Construction Limited | Construction | 2024 |
| SD Acer Projects Ltd | Administrative & support | 2021 |
| SE Jallow Consulting Ltd | Professional & scientific | 2024 |
| Seamatters Ltd | Other services | 2023 |
| Sebo Properties Limited | Real estate | 2021 |
| Sentinel Aviation Investments Limited | Financial services | 2026 |
| Sentinel Aviation Limited | Administrative & support | 2015 |
| Sentinel Logistics Limited | Financial services | 2026 |
| Sfowlerevans Ltd | Wholesale & retail | 2021 |
| Sharp Lines Painting & Decorating Ltd | Construction | 2020 |
| Sheppard Electrical Limited | Construction | 2023 |
| Sherwood and Scott Limited | Real estate | 2022 |
| Shine Time Pressure Washing Ltd | Administrative & support | 2025 |
| Shipquest Ltd | Wholesale & retail | 2018 |
| Shirley Consulting Ltd. | Information & communication | 2017 |
| Shoot and Splice Films Limited | Information & communication | 2019 |
| Showhire Limited | Administrative & support | 2003 |
| Shredcyclesuk Ltd | Wholesale & retail | 2020 |
| Shutter Central Ltd | Manufacturing | 2023 |
| Sidewalk Consulting Limited | Professional & scientific | 2026 |
| Sienna International Limited | Wholesale & retail | 2020 |
| Signal Aldershot Limited | Administrative & support | 2024 |
| Signal Bizhub Group Ltd | Administrative & support | 2013 |
| Signal Bordon Limited | Administrative & support | 2017 |
| Signal South West Ltd | Administrative & support | 2025 |
| Silent Air and Sea Ltd | Transport & logistics | 2023 |
| Silent Transport UK Limited | Transport & logistics | 2012 |
| Silex Limited | Manufacturing | 1985 |
| Simply Distribution UK Ltd | Wholesale & retail | 2007 |
| Sincdata Services Limited | Information & communication | 2017 |
| Sisodiya Holdings Limited | Real estate | 2021 |
| Sisodiya Limited | Wholesale & retail | 2021 |
| Sjpds Limited | Information & communication | 2003 |
| SJZ Property Ltd | Real estate | 2018 |
| Slates and Ladders Roofing and Solar Ltd | Construction | 2025 |
| Smalley & Co Consulting Ltd | Professional & scientific | 2019 |
| Smallworld IT (UK) Limited | Information & communication | 2000 |
| Smallworld Properties Limited | Real estate | 2020 |
| SN Fire & Safety Solutions Ltd | Professional & scientific | 2025 |
| Socialclimb Global Ltd | Professional & scientific | 2022 |
| Solare Engineering Solutions Ltd | Manufacturing | 2019 |
| Sonnet Cloud Ltd | Information & communication | 2022 |
| SOS Accounting Ltd | Professional & scientific | 2026 |
| Sound the Alarm Limited | Information & communication | 2018 |
| Source Heat Pumps Ltd | Construction | 2009 |
| South Atlantic Procurement LLP | | 2019 |
| South East Foods Ltd | Hospitality | 2018 |
| Southapex Ltd | Health & social care | 2026 |
| Southcoast Medics Ltd | Health & social care | 2024 |
| Spa Splash Products Limited | Wholesale & retail | 1998 |
| Sparqlees Limited | Information & communication | 2024 |
| Specialist Autocare Group Ltd | Wholesale & retail | 2015 |
| Spectrum Groupe Limited | Information & communication | 2016 |
| Spencers Court Residents Association Limited | Professional & scientific | 1988 |
| Spooners Turf Limited | Wholesale & retail | 2002 |
| Sprayed Concrete Association | Other services | 1997 |
| Springfield Light Metal and Motor Works Limited | Real estate | 1956 |
| SS Carpet Cleaning Ltd | Administrative & support | 2016 |
| Stable and Ground Ltd | Wholesale & retail | 2020 |
| Staiforce Limited | Information & communication | 2023 |
| Stannel Ltd | Wholesale & retail | 2025 |
| Star Support for YOU Limited | Health & social care | 2018 |
| Starburst Properties Limited | Health & social care | 2008 |
| Start Licensing Ltd | Households | 2002 |
| Station Beauty Ltd | Other services | 2025 |
| Stem Holdings Limited | Financial services | 2023 |
| Stephens & SON (Farms) Limited | Agriculture & fishing | 1958 |
| Stillman Consulting Ltd | Professional & scientific | 2019 |
| Stokes of London Limited | Other services | 2018 |
| Story Bricks Ltd | Professional & scientific | 2025 |
| Stuart J Finch Builders Ltd | Construction | 2014 |
| Stuff'D Ltd | Hospitality | 2024 |
| Stymies (Golf Lane) Management Limited | Households | 1974 |
| Sublime Chocolates Ltd | Manufacturing | 2023 |
| Subsidence Forum Ltd | Other services | 2007 |
| Sundew Consulting Limited | Professional & scientific | 2016 |
| Sunny Days Childcare Ltd | Health & social care | 2022 |
| Supportal UK Ltd | Information & communication | 2015 |
| Supreme Dance Group Limited | Education | 2020 |
| Surestead Solutions Limited | Information & communication | 2003 |
| Surgehospital Limited | Health & social care | 2021 |
| Sutherland Close (Heathervale) Residents Association Limited | Households | 1986 |
| Swallowdiagnostics Ltd | Health & social care | 2024 |
| Swift Glass and Glazing Ltd | Construction | 2021 |
| Sydrich Developments Ltd | Construction | 2021 |
| Symes Fine Kitchens and Interiors Ltd | Manufacturing | 2014 |
| T. King & SON (Groundworks) Limited | Construction | 1975 |
| Tadpole Swim School Limited | Education | 2021 |
| Take One Hire and Supply Ltd | Wholesale & retail | 2023 |
| Tamad Limited | Construction | 2026 |
| Tame the Taxman Ltd | Professional & scientific | 2019 |
| Tansley Photography Ltd. | Professional & scientific | 2003 |
| TAP @ the Shed Ltd | Hospitality | 2021 |
| Tarling Construction Ltd | Construction | 2020 |