| E-Smart Taxis Limited | Wholesale & retail | 2024 |
| E-Sparkle Solutions (Europe) Limited | Manufacturing | 2010 |
| E-Star Nursery Limited | Health & social care | 2025 |
| E-Tech World Ltd | Wholesale & retail | 2017 |
| E-Tts Ltd | Construction | 2025 |
| E-Xprt Ltd | Information & communication | 2023 |
| E. Braude (London) Limited | Manufacturing | 1957 |
| E.B.S. Barker Limited | Wholesale & retail | 1972 |
| E.G.Carr Ltd | Professional & scientific | 2018 |
| E.L. FEE Telecoms Limited | Information & communication | 2018 |
| E1 Brickwork and Property Services Ltd | Construction | 2025 |
| E1 Leisure Ltd | Hospitality | 2023 |
| E4OFFICE Limited | Wholesale & retail | 2014 |
| EA Property North East Ltd | Real estate | 2024 |
| EAD Electrical Ltd | Construction | 2019 |
| EAD Homes Ltd | Real estate | 2026 |
| EAD Properties Ltd | Real estate | 2026 |
| Eaengineering Ltd | Professional & scientific | 2025 |
| Eagle Auto Car Sales Limited | Wholesale & retail | 2022 |
| Eagle Construction (NW) Ltd | Construction | 2015 |
| Eagle Electrical & DIY Limited | Wholesale & retail | 2020 |
| Eagle EYE Brands Ltd | Wholesale & retail | 2024 |
| Eagle Hygiene & Safety Consultants Ltd | Professional & scientific | 2018 |
| Eagley Accounting Limited | Professional & scientific | 2019 |
| Eagley Angling Limited | Agriculture & fishing | 2016 |
| Eagley Brook Limited | Real estate | 2024 |
| Eagley Infant School | Education | 2012 |
| Eagley Junior School | Education | 2012 |
| Eagley School House Nursery Ltd | Education | 2003 |
| EAP Consulting (Healthcare) Ltd | Health & social care | 2015 |
| Eapharm Ltd | Health & social care | 2019 |
| Earful Ltd | Wholesale & retail | 2021 |
| Earldale Limited | Construction | 2020 |
| Early Brew Cafe Ltd | Hospitality | 2026 |
| Earl’S Day & Night Deli Limited | Wholesale & retail | 2023 |
| Earth Evolution Ltd | Wholesale & retail | 2019 |
| Earth Exchange UK Limited | Wholesale & retail | 2022 |
| Earth's Crust Resources Limited | Extraterritorial | 2020 |
| Earthie Organics Ltd | Wholesale & retail | 2025 |
| Earthwork Support Specialist (CE) Limited | Construction | 2020 |
| Earthworks North West Ltd | Construction | 2018 |
| Earthworks Northwest Holdings Ltd | Professional & scientific | 2019 |
| Ease Consultancy Ltd | Professional & scientific | 2023 |
| Ease Your Debts Limited | Other services | 2019 |
| Easi-Chock Limited | Administrative & support | 2012 |
| Easi-Chock Solutions Ltd | Administrative & support | 2024 |
| Easiflow Ventilation Limited | Construction | 2022 |
| Easily Sourced Ltd | Real estate | 2019 |
| East Glow Limited | Administrative & support | 2025 |
| East India Propco Ltd | Real estate | 2020 |
| East Lancashire Property & Land Developments Ltd | Households | 2020 |
| East Neuk Trials Motorcycles Limited | Wholesale & retail | 2014 |
| East Sing 88 Limited | Extraterritorial | 2020 |
| Eastbank Management Company (Bolton) Limited | Households | 2020 |
| Eaststone Limited | Manufacturing | 2007 |
| Eastwood Mortgages Ltd | Other services | 2023 |
| Easy AS Ecom Ltd | Wholesale & retail | 2023 |
| Easy Buyz Limited | Other services | 2024 |
| Easy Equipment Limited | Wholesale & retail | 2005 |
| Easy Going Fashion Limited | Wholesale & retail | 2019 |
| Easy Life Properties Ltd | Real estate | 2021 |
| Easy Move (Bolton) Ltd | Real estate | 2007 |
| Easy PC Training Limited | Information & communication | 2004 |
| Easy Shopping Limited | Wholesale & retail | 2024 |
| Easy-Breeze Windows Limited | Manufacturing | 2019 |
| Easybuy Hub Ltd | Wholesale & retail | 2024 |
| Easygoodsuk Group Limited | Wholesale & retail | 2021 |
| Easyhomes NW Ltd | Construction | 2019 |
| Easylawn Turf Supplies Limited | Administrative & support | 2002 |
| Easymove Westhoughton Ltd | Real estate | 2023 |
| EAT & Breathe Ltd | Professional & scientific | 2014 |
| EAT Move Sleep Retreat Ltd | Extraterritorial | 2021 |
| Eating With Husna Ltd | Hospitality | 2026 |
| EB 1ST Call Cars Ltd | Transport & logistics | 2023 |
| EB Clinical Psychology Service Limited | Administrative & support | 2016 |
| Ebaa Barbers Bolton Ltd | Other services | 2025 |
| Ebamas Services Ltd | Health & social care | 2022 |
| EBB Consultancy Limited | Administrative & support | 2020 |
| Ebby Analytics Ltd | Financial services | 2018 |
| Ebenezer Care Ltd | Health & social care | 2014 |
| EBI Logistics Ltd | Transport & logistics | 2018 |
| Ebike Capital Ltd | Manufacturing | 2018 |
| EBM Risk Consulting Ltd | Administrative & support | 2017 |
| EBO BIO Solution Ltd | Wholesale & retail | 2025 |
| Ebo's Barbers Ltd | Other services | 2022 |
| Ebony Nicole Cosmetics Limited | Manufacturing | 2020 |
| Ebra Properties Limited | Real estate | 2016 |
| EC Global Limited | Professional & scientific | 2007 |
| Ecars Limited | Wholesale & retail | 2005 |
| Ecave Ltd | Wholesale & retail | 2022 |
| Eccles QS Services Ltd | Professional & scientific | 2023 |
| ECG the Jesus Nation Church-Manchester CIC | Other services | 2024 |
| Echelon & Co. Ltd | Professional & scientific | 2025 |
| Echo and Wave CIC | Education | 2026 |
| Echo Consult Limited | Real estate | 2017 |
| Echo Electronics Ltd | Wholesale & retail | 2025 |
| Echo Fusion Ltd | Administrative & support | 2016 |
| Eckersley Sprinklers Ltd | Professional & scientific | 2014 |
| Eclear Technologies Limited | Information & communication | 2013 |
| Eclectic Rhythm Ltd | Professional & scientific | 2013 |