| DON Tacos Ltd | Hospitality | 2023 |
| Don'T BE Chai Ltd | Hospitality | 2025 |
| Don'T Throw in the Trowel! Ltd | Agriculture & fishing | 2023 |
| Dona Bees Ltd | Wholesale & retail | 2023 |
| Doner's Empire Ltd | Hospitality | 2018 |
| Donlo Ltd | Administrative & support | 2023 |
| Donna Hall Consulting Limited | Professional & scientific | 2019 |
| DONNER24 Express Ltd | Hospitality | 2025 |
| Donoghue Portfolio Ltd | Professional & scientific | 2021 |
| Donsteph Painting & Decorating Limited | Construction | 2017 |
| Dooley Investments Ltd | Other services | 2019 |
| Doolittle Doggy Daycare and Groomers Ltd | Wholesale & retail | 2024 |
| DOORS2FLOORS UK Ltd | Wholesale & retail | 2017 |
| Doorstep Gadget Repairs Ltd | Other services | 2025 |
| Dora Estates Ltd | Real estate | 2026 |
| Dora Flowers Ltd | Wholesale & retail | 2025 |
| DORACK9SERVICES Ltd | Agriculture & fishing | 2025 |
| Dorcas Management Limited | Real estate | 2017 |
| Dorelson Limited | Wholesale & retail | 2023 |
| Doric Developments Ltd | Extraterritorial | 2011 |
| Doric Knight Limited | Professional & scientific | 2023 |
| Dorlux Beds (2005) Ltd | Professional & scientific | 2004 |
| Dormer Electrical Contractors Limited | Construction | 2014 |
| Dorrian Mews Limited | Households | 1998 |
| Dorton's Bacon Supplies Limited | Wholesale & retail | 2001 |
| DOTMO1 Healthcare Limited | Health & social care | 2012 |
| Dott Property Management Limited | Real estate | 2025 |
| Double Decker Security Limited | Information & communication | 2025 |
| Double O Health Care Services Limited | Health & social care | 2023 |
| Double U Ophthalmics Ltd | Health & social care | 2017 |
| Douglas Heating Limited | Construction | 2013 |
| Douglas Scott Legal Recruitment Limited | Administrative & support | 2004 |
| Douglas Skeeles Limited | Wholesale & retail | 1960 |
| Douglas Valley Golf Driving Range Limited | Real estate | 1998 |
| Dove Kitchens & Bathrooms Limited | Wholesale & retail | 2011 |
| Dove Photography Media and Entertainment Limited | Information & communication | 2026 |
| Dovebank Developments Limited | Real estate | 1996 |
| Dovedwin Property Ltd | Real estate | 2019 |
| Doveleys Properties Limited | Real estate | 2020 |
| Dovepoint Limited | Wholesale & retail | 1992 |
| Dovetail Consultants Limited | Health & social care | 2008 |
| Dovetail Healthcare Events Limited | Administrative & support | 2013 |
| Down to Earth Aromatherapy Products Ltd | Extraterritorial | 2017 |
| Down Under Properties Ltd | Real estate | 2023 |
| Downton Solutions Ltd | Professional & scientific | 2019 |
| Downtown Bolton Limited | Hospitality | 2025 |
| DP Beauty and Health Distribution Ltd | Wholesale & retail | 2024 |
| DP Consultants NW Limited | Information & communication | 2017 |
| DP Driving Services Limited | Transport & logistics | 2022 |
| DP Mechanical Limited | Construction | 2015 |
| DP1 Ltd | Professional & scientific | 2022 |
| Dpai Limited | Information & communication | 2024 |
| DPB Support Services Limited | Administrative & support | 2025 |
| DPE Systems Limited | Other services | 2009 |
| DPM Developments Ltd | Real estate | 2016 |
| DPM Holdings NW Limited | Financial services | 2021 |
| Dpmdefence Ltd | Professional & scientific | 2018 |
| DPS Transport Ltd | Transport & logistics | 2024 |
| Dpwellness Ltd | Health & social care | 2025 |
| DPX Engineering Solutions Ltd | Professional & scientific | 2025 |
| DR Ahsan Aesthetics Ltd | Health & social care | 2023 |
| DR Alistair (Medical Services) Limited | Health & social care | 2008 |
| DR and Skin Ltd | Health & social care | 2025 |
| DR FAB Medical Services Ltd | Health & social care | 2024 |
| DR Heating & Plumbing Ltd | Construction | 2026 |
| DR Heating NW Ltd | Construction | 2020 |
| DR Ibrahim Dental Ltd | Health & social care | 2023 |
| DR Lamia Zafrani Ltd | Health & social care | 2025 |
| DR Mariam Ltd | Health & social care | 2022 |
| DR Matthew Wood Ltd | Health & social care | 2024 |
| DR MB Salim Ltd | Health & social care | 2019 |
| DR Meng & Herbs Ltd | Wholesale & retail | 2009 |
| DR Naseef Limited | Real estate | 2009 |
| DR P George & Associates Limited | Health & social care | 2015 |
| DR PGB Aesthetic Ltd | Health & social care | 2023 |
| DR R C Prudham Ltd | Health & social care | 2015 |
| DR Rehab Ltd | Other services | 2018 |
| DR Saabb Limited | Health & social care | 2017 |
| DR Syed Nasaruddin Limited | Health & social care | 2012 |
| DR Webster Ltd | Other services | 2021 |
| DR. Twilight Ltd | Construction | 2018 |
| Drago's Gym Ltd | Arts & recreation | 2022 |
| Dragon Order Limited | Hospitality | 2021 |
| Dragon Publishing Group Ltd | Information & communication | 2026 |
| Dragonbase Ltd | Hospitality | 2022 |
| Dragonfly Content Limited | Administrative & support | 2019 |
| Dragonfly Crowd Limited | Financial services | 2019 |
| Drain-Serv (M/Cr) Ltd. | Administrative & support | 2008 |
| Drake Hall Limited | Real estate | 2004 |
| Drake Mill Storage Solutions Limited | Transport & logistics | 2018 |
| Drake QS Limited | Professional & scientific | 2011 |
| Drakes Properties Ltd | Construction | 2019 |
| Draper Engineering Consultants Ltd | Professional & scientific | 2025 |
| Drastic Brain Ltd | Information & communication | 2025 |
| Draughty Crafts Ltd | Manufacturing | 2022 |
| Draxel Ltd | Wholesale & retail | 2025 |
| Drcarpys & Nwbait LAB Limited | Wholesale & retail | 2026 |
| Dream & Desire Limited | Wholesale & retail | 2021 |
| Dream Clean Solutions Limited | Other services | 2014 |
| Dream Craft Beds Ltd | Manufacturing | 2024 |