| Melbourne Limited | Real estate | 2022 |
| Melbourne Management Limited | Real estate | 2022 |
| Melco Limited | Wholesale & retail | 1980 |
| Melfin Limited | Administrative & support | 2005 |
| Melfinco Limited | Administrative & support | 2013 |
| Melia Melts Ltd | Manufacturing | 2023 |
| Melior Products Limited | Wholesale & retail | 2015 |
| Melling Farm and Equine Limited | Financial services | 2025 |
| Melling Pharmacy Limited | Wholesale & retail | 2002 |
| Mello Bolton Errands Limited | Health & social care | 2023 |
| Mellor Coachcraft Limited | Other services | 1992 |
| Mellor Tops Maintenance Limited | Manufacturing | 1998 |
| Mellow CLO Ltd | Wholesale & retail | 2024 |
| Meloc Engineering Service Ltd | Professional & scientific | 2024 |
| Melodyhouse Supply Limited | Wholesale & retail | 2025 |
| Melrose Court (Kearsley) Limited | Real estate | 2013 |
| Melrose Property Services North West Limited | Real estate | 2016 |
| Melt Creative Limited | Information & communication | 2012 |
| Meltdown Therapy Ltd | Manufacturing | 2026 |
| MEM Electrical Services Ltd | Construction | 2019 |
| Membop 12 Limited | Administrative & support | 2022 |
| Meme Manor Limited | Hospitality | 2016 |
| Men's Room Nice Barber Shop Ltd | Other services | 2021 |
| Menrad Optics Limited | Wholesale & retail | 1978 |
| Mental Health in Society Training (Mhist) Ltd | Professional & scientific | 2016 |
| Mentec Ltd | Transport & logistics | 2019 |
| Mentionhk Ltd | Education | 2022 |
| Menu Masters Caterers Ltd | Hospitality | 2025 |
| Menzi Properties Ltd | Hospitality | 2025 |
| MEO Holdings Ltd | Financial services | 2025 |
| MEO Limited | Wholesale & retail | 2016 |
| Meow Communications Limited | Administrative & support | 2017 |
| Merab Ahmed Ltd | Wholesale & retail | 2024 |
| Mercatura (E-C) Limited | Professional & scientific | 2016 |
| Merchants' Bakehouse Ltd | Hospitality | 2026 |
| Mercury Detailing Ltd | Administrative & support | 2025 |
| Mercury Station (Westhoughton) Ltd | Wholesale & retail | 2007 |
| Merdan Trading Ltd | Wholesale & retail | 2024 |
| Merelawn Limited | Households | 1984 |
| Meridian Driver Ltd | Administrative & support | 2008 |
| Meridian Van Sales Warrington Limited | Wholesale & retail | 2024 |
| Meristep Limited | Education | 2021 |
| Merit Motors Ltd | Wholesale & retail | 2022 |
| Meritus Encompass Ltd | Health & social care | 2023 |
| Merlin Engineering (Bolton) Limited | Manufacturing | 1977 |
| Merlin HIP Solutions Limited | Professional & scientific | 2008 |
| Merlin House (Echo) Limited | Health & social care | 2023 |
| Merlin Van Centre Ltd | Wholesale & retail | 2026 |
| Mero Smiles Ltd | Health & social care | 2025 |
| Merritts for Hair Online Limited | Wholesale & retail | 2011 |
| Merryfield RTM Company Ltd | Real estate | 2010 |
| Mersey Seafood Ltd | Wholesale & retail | 2023 |
| MES Conway Limited | Professional & scientific | 2017 |
| MES Electric and Security Ltd | Administrative & support | 2023 |
| Mesafe Limited | Professional & scientific | 2018 |
| Message & Momentum Limited | Other services | 2025 |
| Messinian Luxury Ltd. | Real estate | 2018 |
| Meta ERP Ltd | Information & communication | 2022 |
| Meta Plastics Ltd | Other services | 2019 |
| Metabolize Ltd | Health & social care | 2024 |
| Metafores Ltd | Transport & logistics | 2006 |
| Metal Solutions Limited | Manufacturing | 2010 |
| Metal Solutions Systems Limited | Manufacturing | 2019 |
| Metaleap Ltd | Wholesale & retail | 2024 |
| Metalink Ltd | Water & waste | 2021 |
| Metamuse Systems Ltd | Information & communication | 2025 |
| Metarux Solutions Ltd | Information & communication | 2018 |
| Metatron's Cube Ltd | Information & communication | 2023 |
| Metavative Ltd | Information & communication | 2025 |
| Metcon Strength and Fitness Limited | Arts & recreation | 2025 |
| Methods MCR Limited | Real estate | 2024 |
| Metier Events Limited | Administrative & support | 1999 |
| Metigen Limited | Mining & quarrying | 2014 |
| Metis & Muse Limited | Professional & scientific | 2026 |
| Metis Associates Inc Ltd | Information & communication | 2013 |
| Metland Commercial Services Limited | Professional & scientific | 2016 |
| Metric Construction (Holdings) Limited | Real estate | 2000 |
| Metric Construction (Nazarene Court) Limited | Real estate | 2005 |
| Metric Labs Ltd | Professional & scientific | 2026 |
| Metro Cars North West Limited | Transport & logistics | 2009 |
| Metro Community Boxing Gym CIC | Arts & recreation | 2021 |
| Metro Guard Security Ltd | Administrative & support | 2024 |
| Metro Salvage NW Limited | Wholesale & retail | 2014 |
| Metro Troci Carwash Limited | Administrative & support | 2024 |
| Metro Troci Tyres Limited | Manufacturing | 2024 |
| Metro Tyres & Autocare Ltd | Wholesale & retail | 2023 |
| Metro Tyres of Bolton Ltd | Wholesale & retail | 2019 |
| Metropolis Estates Ltd | Real estate | 2020 |
| Metropolis Housing Group Ltd | Real estate | 2005 |
| Metropolis Systems Limited | Real estate | 2002 |
| Metrotech Solutions Limited | Information & communication | 2012 |
| Metsite Limited | Manufacturing | 2007 |
| Meturon Limited | Manufacturing | 2025 |
| Mevlana Coffee House Bolton Limited | Hospitality | 2022 |
| Mevlana Express Ltd | Hospitality | 2025 |
| Mevlana Restaurant Bolton Ltd | Hospitality | 2022 |
| Mexcourt Properties Limited | Real estate | 2007 |
| Mexican Villa Limited | Hospitality | 2022 |
| Mezze Restaurant NW Limited | Hospitality | 2024 |
| MF Auto Finish Ltd | Wholesale & retail | 2022 |