| Richard Schofield Limited | Financial services | 2010 |
| Richards Plumbing & Heating Ltd | Construction | 2011 |
| Richardson Electrical Services Limited | Construction | 2022 |
| Ricky Scientific Platforms Ltd | Administrative & support | 2025 |
| Rimmer Consultancy Services Ltd | Information & communication | 2012 |
| Ritzbury Limited | Construction | 1975 |
| Riverside (Rope Walk) Management Limited | Households | 1994 |
| RJM Plumbing and Heating Limited | Construction | 2022 |
| RMY Ltd | Administrative & support | 2020 |
| Road Incident Management Systems Ltd | Wholesale & retail | 2019 |
| Robins Holdings Ltd | Professional & scientific | 2021 |
| Rock Gardens (Bognor Regis) RTM Company Limited | Administrative & support | 2009 |
| Rockhopper Pools Limited | Other services | 2016 |
| Roger Clayden Limited | Wholesale & retail | 2003 |
| Rolly's Records Limited | Wholesale & retail | 2021 |
| Roman Pavlyshyn Ltd | Transport & logistics | 2025 |
| Romeo's Enterprises Ltd | Construction | 2025 |
| Ronald's Legacy Limited | Wholesale & retail | 2015 |
| Roodhouse Project Management Limited | Professional & scientific | 2026 |
| Roofing and Property Solutions Ltd | Construction | 2025 |
| Roots & Rivers CIC | Education | 2026 |
| Rosalia Limited | Health & social care | 2022 |
| Rose Green Fryery Limited | Hospitality | 2017 |
| Rose Green W.A. Limited | Wholesale & retail | 2005 |
| Rosewood Foods Ltd | Hospitality | 2024 |
| Rosewood Funerals Ltd | Other services | 2022 |
| Rosewood Projects Ltd | Administrative & support | 2020 |
| Roundle Glass & Glazing Limited | Construction | 2001 |
| Roundle Installations Limited | Manufacturing | 2014 |
| Route Drop Ltd | Transport & logistics | 2025 |
| ROX Music and Arts | Arts & recreation | 2012 |
| ROY Sargeant Carpets & Vinyls Limited | Construction | 2010 |
| Royal Norfolk Mews Management Limited | Other services | 2008 |
| Rozi BEE Ltd | Wholesale & retail | 2022 |
| RPF Associates Ltd | Construction | 2001 |
| RPJ Developments Limited | Construction | 2010 |
| Rprm Premium Service Ltd | Transport & logistics | 2025 |
| RS Household Property Maintenance Ltd | Construction | 2019 |
| RT Renovations and Maintenance Limited | Construction | 2016 |
| RTF Imaging Limited | Construction | 2015 |
| Ruby Nails-Spa Ltd | Other services | 2024 |
| Rural and Urban Estates Limited | Real estate | 1971 |
| Rusoke Services Limited | Health & social care | 2021 |
| Russ Windows Commercial Ltd | Administrative & support | 2025 |
| Rwpgroup Ltd | Manufacturing | 2011 |
| Ryanfithub Ltd | Arts & recreation | 2020 |
| S & C Plan Ltd | Construction | 2025 |
| S & P Tree Specialists Limited | Administrative & support | 2002 |
| S Eggins Limited | Administrative & support | 2012 |
| S Harmour Bathrooms & Plumbing Limited | Construction | 2021 |
| S M P & Co Ltd | Other services | 2015 |
| S&H Leisure Ltd | Hospitality | 2019 |
| S&L (2021) Ltd | Construction | 2020 |
| S&P Traders Ltd | Wholesale & retail | 2024 |
| S&T Living Ltd | Real estate | 2026 |
| S. Ship Landscapes Limited | Administrative & support | 2022 |
| S.B.H. (Engineering) Limited | Extraterritorial | 1979 |
| S.Efstratiou Consulting Ltd | Health & social care | 2024 |
| S.J.H Blade Repair Limited | Manufacturing | 2025 |
| S.S.C. Toone Ltd | Construction | 2020 |
| S3K Events Limited | Financial services | 2020 |
| S3K Group Limited | Financial services | 2020 |
| S3K Limited | Professional & scientific | 2008 |
| Sadler Services Ltd | Construction | 2019 |
| Saffron Court Flats Ltd | Extraterritorial | 2024 |
| Saffrons Court (Worthing) Ltd | Real estate | 2004 |
| Saint Georges Park (Barnham) Residents Management Company Limited | Households | 2023 |
| Sales Journey Limited | Education | 2021 |
| Salisbury House Residents Management Company Limited | Households | 2024 |
| Salix Projects Limited | Construction | 2003 |
| Salthouse Place Management Company Limited | Real estate | 2003 |
| Saltwater Creations CIC | Education | 2025 |
| Saltwater Sessions CIC | Education | 2015 |
| Salus Joy Ltd | Arts & recreation | 2009 |
| Samantha Nichole Hearne Limited | Extraterritorial | 2024 |
| Samantha Nichole Osborne Limited | Extraterritorial | 2024 |
| Samantha Thompson Limited | Professional & scientific | 2012 |
| Sandham Place Residents Management Company Limited | Households | 2017 |
| Sandlands Point Management Company Limited | Households | 2019 |
| Sandle Estate Ltd | Real estate | 2023 |
| Sandpipers Restaurant | | 1995 |
| Sandy's Salt and Softeners Limited | Construction | 2020 |
| Sapexpert Limited | Information & communication | 2014 |
| Sapphire Leaseholds Ltd | Real estate | 2026 |
| Sapphire Signature Food Ltd | Hospitality | 2026 |
| Sargeant Carpets Ltd | Wholesale & retail | 2005 |
| Satyr Design Limited | Wholesale & retail | 1998 |
| Satyr Holdings Ltd | Real estate | 2021 |
| Sawdan Limited | Wholesale & retail | 2021 |
| Saxby Sussex Limited | Health & social care | 2014 |
| Saxon Close (Pagham) Limited | Households | 2018 |
| Saxton Trading Limited | Wholesale & retail | 2011 |
| Sayres Limited | Manufacturing | 2015 |
| SB Carpentry (Southern) Limited | Construction | 2022 |
| SBD Build Limited | Construction | 2017 |
| Scalology Ltd | Wholesale & retail | 2017 |
| Scanstation Computers Ltd | Wholesale & retail | 2009 |
| Scarletina Films Ltd | Information & communication | 2022 |
| Sceats Ltd | Professional & scientific | 2024 |
| Scentcentre Ltd | Wholesale & retail | 2020 |