| Omelia Signs Ltd | Professional & scientific | 2025 |
| ON the Trash Waste Removal Ltd | Water & waste | 2024 |
| OPTIMIST5 Ltd | Construction | 2025 |
| ORE Catapult Development Services Limited | Professional & scientific | 2005 |
| OSL Energy & Infrastructure Limited | Professional & scientific | 2025 |
| Ozdemir NE Ltd | Hospitality | 2021 |
| P a Flooring Ltd | Construction | 2022 |
| P H Armstrong Ltd | Professional & scientific | 2018 |
| P5 Properties Limited | Real estate | 2014 |
| Panahar Indian Restaurant Ltd | Hospitality | 2021 |
| Park Farm Barns Management Company Limited | Households | 2010 |
| Paul Bertram Painting & Decorating Limited | Construction | 2022 |
| Pauljrowland Holdings Ltd. | Professional & scientific | 2021 |
| Peggy's Parlour Limited | Other services | 2014 |
| Peking House Blyth Ltd | Hospitality | 2025 |
| Pelican Theatre Ltd | Arts & recreation | 2021 |
| Pentland Music Limited | Arts & recreation | 2017 |
| People Uplifting Resilient Parents Little Ones & Everyone (Purple) CIC | Education | 2026 |
| Percheron Consulting Ltd | Professional & scientific | 2026 |
| Percy House Limited | Health & social care | 2008 |
| Peter Norvell's BIN Boutique Limited | Administrative & support | 2006 |
| Peter Taylor (Oldcotes) Limited | Agriculture & fishing | 1953 |
| Pgps Constructions Ltd | Construction | 2026 |
| PH Bolting Ltd | Professional & scientific | 2024 |
| Pharos Offshore Group Limited | Professional & scientific | 2011 |
| PHD Plastics Limited | Wholesale & retail | 2004 |
| Phoenix Taxis (North East) Limited | Administrative & support | 1985 |
| Phoenix Taxis Group Limited | Professional & scientific | 2024 |
| Phoenix Taxis Topco Limited | Professional & scientific | 2024 |
| Phoenix Theatre (Blyth) | Arts & recreation | 2012 |
| Pipeline Protection (N.E.) Limited | Construction | 2004 |
| Pitt Street Accommodation Limited | Extraterritorial | 2012 |
| Pizza Park Limited | Hospitality | 2022 |
| Pizza YES Limited | Hospitality | 2024 |
| Platinum Cloud Solutions Ltd | Information & communication | 2023 |
| Plessey Convenience Store Ltd | Wholesale & retail | 2024 |
| Plessey News (Blyth) Limited | Wholesale & retail | 2004 |
| Plumbtechne Ltd | Construction | 2025 |
| Plyable Design Limited | Manufacturing | 2017 |
| Poets Corner (Blyth) Limited | Wholesale & retail | 2016 |
| Point Three Skin Limited | Wholesale & retail | 2021 |
| Porkys Food Limited | Hospitality | 2019 |
| Port Marine Safety Limited | Other services | 2015 |
| Practical Admin Support Ltd. | Public administration | 2019 |
| Practical Wellbeing LLP | | 2018 |
| PRD Engineering Consultancy Limited | Professional & scientific | 2020 |
| Premier BUS and Coach Limited | Transport & logistics | 2004 |
| Premier Graphics Ltd | Manufacturing | 2015 |
| Prestige Safety Solutions Ltd | Health & social care | 2018 |
| Pretty Shabby 101 Ltd | Other services | 2020 |
| Prime Meats NE Ltd | Wholesale & retail | 2026 |
| Professional Appliance Care Ltd | Other services | 2007 |
| Project U Fitness Ltd | Arts & recreation | 2018 |
| Projects in Fiducia Ltd | Real estate | 2021 |
| Prop and Snap Event Hire Ltd | Other services | 2025 |
| Prox Media Limited | Information & communication | 2024 |
| PSS Tech Ltd | Information & communication | 2025 |
| Pulcea (OWF) Ltd | Professional & scientific | 2025 |
| Punjabi Virsa North East UK Ltd | Education | 2023 |
| Purple Patch Motor Services Ltd | Wholesale & retail | 2018 |
| Pvolt Energy Ltd | Professional & scientific | 2025 |
| Qixo Ltd | Information & communication | 2025 |
| Quantum Design Services Limited | Professional & scientific | 2016 |
| Quay Marketing Limited | Construction | 2019 |
| R & MK Properties Ltd | Real estate | 2022 |
| R Armstrong Limited | Extraterritorial | 2012 |
| R Spence Mechanical Limited | Mining & quarrying | 2024 |
| R.G.E.I.A.& Co Ltd | Hospitality | 2025 |
| Raceforvalue Ltd | Extraterritorial | 2025 |
| Rail Estate Search Ltd | Professional & scientific | 2021 |
| Rail IQA Limited | Professional & scientific | 2019 |
| Rail Training Limited | Professional & scientific | 2019 |
| RAN Scaffolding & Roofing Ltd | Construction | 2025 |
| Rapier Construction Limited | Construction | 2005 |
| RAS Leisure Limited | Hospitality | 2023 |
| RAS Property Holdings Ltd | Real estate | 2019 |
| RB Groundworks and Fencing Ltd | Administrative & support | 2017 |
| RB Kitchen Installations Limited | Construction | 2018 |
| RC PPS Ltd | Mining & quarrying | 2023 |
| Readypay Limited | Administrative & support | 1990 |
| Reay Security Holdings Limited | Financial services | 2017 |
| Reay Security Limited | Other services | 1994 |
| Reay Security Properties Limited | Other services | 2017 |
| Rebecca Maxwell Tutoring Ltd | Education | 2025 |
| Recon Build Co Limited | Construction | 2026 |
| Redwood Business Services Limited | Information & communication | 2016 |
| Reed & Co Services Limited | Construction | 2023 |
| Refined Radiance Clinic Ltd | Other services | 2025 |
| Republic Gallery CIC | Arts & recreation | 2021 |
| RES Courier Services Ltd | Transport & logistics | 2019 |
| Restoration Parts Ltd | Wholesale & retail | 2019 |
| RH Residential Ltd | Real estate | 2025 |
| Richardson's Bathrooms & Boilers Limited | Wholesale & retail | 2022 |
| Riverdene Dental Laboratory Limited | Manufacturing | 2024 |
| RJ Bolting and Mechanical Services Limited | Manufacturing | 2025 |
| RMP Group Services Ltd. | Administrative & support | 2012 |
| Robin Palmer PR Limited | Professional & scientific | 2011 |
| Robox Limited | Wholesale & retail | 2025 |
| Robtic Ltd | Wholesale & retail | 2020 |
| Roco (Blyth) Limited | Mining & quarrying | 2013 |