| Dryden Roofing Ltd | Construction | 2018 |
| DT Construction Solutions Ltd | Construction | 2024 |
| Dubois Electrical Services Ltd | Construction | 2017 |
| Dvob Limited | Hospitality | 2024 |
| Dynemo Limited | Professional & scientific | 2024 |
| E Sekure Ltd | Administrative & support | 2021 |
| Earle Hall Design Ltd | Professional & scientific | 2018 |
| Earle R Hall Drawing Services Limited | Professional & scientific | 2005 |
| Earth Metric Solutions Ltd | Professional & scientific | 2026 |
| Eastern Balti Blyth Ltd | Hospitality | 2022 |
| Eco-Tilities + Ltd | Professional & scientific | 2021 |
| Ecoheat (North East) Limited | Construction | 2022 |
| Edable Architecture Ltd. | Professional & scientific | 2015 |
| EFR Engineering Ltd | Professional & scientific | 2018 |
| Eighteen Real Estate Limited | Real estate | 2021 |
| Elan Solutions Ltd | Professional & scientific | 2019 |
| Elite Bookkeeping NE Ltd | Professional & scientific | 2010 |
| Elliot Financial Consultancy Limited | Professional & scientific | 2024 |
| EMK Development Properties Ltd | Real estate | 2023 |
| Emma Jacobs Nicholson Ltd | Financial services | 2022 |
| Emmanuel Academy Services Limited | Wholesale & retail | 2013 |
| Emmanuel Schools Foundation | Education | 2002 |
| Empowered Community C.I.C. | Education | 2024 |
| END2END Property Group Ltd | Real estate | 2024 |
| Energy Central Campus Limited | Education | 2021 |
| Ennerdale Court Estates Limited | Real estate | 2019 |
| Ennerdale Court Management Limited | Real estate | 2019 |
| Ennerdale Court Warehousing Limited | Real estate | 2023 |
| Enprops Ltd | Real estate | 2025 |
| Enshore Subsea Assets Limited | Financial services | 2025 |
| Enshore Subsea Limited | Construction | 2021 |
| Enshore Subsea Rapidscan Limited | Construction | 2025 |
| Enterprise Propco Holdings Limited | Financial services | 2025 |
| Enterprise Propco Limited | Real estate | 2025 |
| Entrusted Content Ltd | Professional & scientific | 2012 |
| Entrusted Property Ltd | Hospitality | 2012 |
| Enzlin Ltd | Transport & logistics | 2025 |
| ERW Technical Services Ltd | Professional & scientific | 2026 |
| Escaperoomsuk Limited | Arts & recreation | 2015 |
| European Billiards & Snooker Association Ltd | Other services | 2013 |
| Evol Group Ltd | Professional & scientific | 2025 |
| Expertise Wills and Wealth Limited | Financial services | 2014 |
| Express Offshore Medicals North East Ltd | Health & social care | 2025 |
| F&H Dixon Property Investments Ltd | Real estate | 2026 |
| Fairholme 1982 Limited | Financial services | 2022 |
| Farey Construction Limited | Real estate | 2001 |
| Fari's Barber Blyth Ltd | Other services | 2024 |
| Farsight Holdings Limited | Financial services | 2024 |
| Favour Hall Property Ltd | Real estate | 2026 |
| Feel the Magic Entertainment Ltd | Arts & recreation | 2021 |
| Fifty Eight North East Ltd | Real estate | 2025 |
| First Stop Tyres & Repairs Cramlington Ltd | Wholesale & retail | 2025 |
| FJS Blagdon Limited | Real estate | 2004 |
| Flipping Well Ltd | Real estate | 2025 |
| FN Business Solutions Limited | Information & communication | 2014 |
| Forager Films Limited | Information & communication | 2001 |
| Forbliss Ltd | Wholesale & retail | 2025 |
| Foreoax Limited | Wholesale & retail | 2010 |
| Forget ME NOT Funeral Service Ltd | Other services | 2019 |
| Freeflo Performance Limited | Manufacturing | 2026 |
| Frisk Radio Ltd | Information & communication | 2020 |
| Full Circle Recovery CIC | Health & social care | 2021 |
| Fusion PR (UK) Limited | Professional & scientific | 2013 |
| G K Clean Ltd | Administrative & support | 2025 |
| G&J Wind Services Ltd | Construction | 2025 |
| G&K MOT Centre Ltd | Wholesale & retail | 2025 |
| Gareth Beddow Fitness Ltd | Arts & recreation | 2025 |
| Garratt CRE8TIVE Co Ltd | Professional & scientific | 2026 |
| GB Event Ice Cream Limited | Hospitality | 2006 |
| Geco Developments Ltd | Construction | 2022 |
| Gecor Ltd | Construction | 2023 |
| Gemma Louise Academy Limited | Education | 2025 |
| Gemma Louise Hair & Beauty Limited | Other services | 2025 |
| Gentle Aura Aesthetics Limited | Other services | 2025 |
| Geo-Dev Ltd | Construction | 2014 |
| George Consultancy (NE) Ltd | Health & social care | 2019 |
| GET Wired Electrical Services Ltd | Construction | 2023 |
| GFM (North East) Ltd | Construction | 2026 |
| Gingerfizz Ltd | Extraterritorial | 2013 |
| Gino's Fish Inn Ltd | Hospitality | 2017 |
| Girls WHO Play CIC | Education | 2020 |
| Gkays Ltd | Health & social care | 2023 |
| Glitzylady Ltd | Other services | 2019 |
| Glory to OUR Lord and Saviour Jesus Christ! Ltd | Manufacturing | 2023 |
| GM Labour Services Ltd | Manufacturing | 2025 |
| GM Piping & Mechanical Services Ltd | Construction | 2026 |
| Gmhse Services Limited | Administrative & support | 2023 |
| Go Green Recycling Ltd | Water & waste | 2019 |
| Good Skin North East Ltd | Wholesale & retail | 2022 |
| Gordie Properties Ltd | Real estate | 2025 |
| Grab and Bites Ltd | Hospitality | 2025 |
| Grande Investments Ltd | Financial services | 2019 |
| Green Army MIL Ltd | Administrative & support | 2026 |
| Green Lane Property Ltd | Real estate | 2015 |
| Green's Scaffolding Services Ltd | Construction | 2018 |
| Greenacre and Sons Joinery Limited | Construction | 2025 |
| Greenacre Electrical Services Limited | Construction | 2006 |
| Gregorio Holdings Limited | Financial services | 2015 |
| Greymatter Cyber Ltd | Information & communication | 2026 |
| GT Roofing Contractors Ltd | Construction | 2020 |