| Discount Furniture Import Ltd | Wholesale & retail | 2026 |
| DJM Estates (Wales) Ltd | Real estate | 2011 |
| DJM Rentals Ltd | Real estate | 2024 |
| DLR Bodyshop Ltd | Wholesale & retail | 2024 |
| Donnies Burgers Limited | Hospitality | 2026 |
| Donnies Takeaways Limited | Hospitality | 2026 |
| DR Emma Howard Consultant Dermatologist Limited | Health & social care | 2018 |
| Dragon Carpentry TV & Film Limited | Construction | 2011 |
| Dragon Fabrications & Commercial Body Builders Limited | Manufacturing | 2009 |
| Dragon Insulations Limited | Construction | 2024 |
| Dragon Mobile Zone Ltd | Wholesale & retail | 2021 |
| Dragon Windows & Doors Limited | Manufacturing | 2013 |
| Dream 365 Ltd | Wholesale & retail | 2025 |
| Driven (UK) Limited | Transport & logistics | 2006 |
| Driver Management Training Services Limited | Administrative & support | 2009 |
| Dryclean'D Ltd | Other services | 2024 |
| Duetcare Ltd | Health & social care | 2021 |
| Duggan Plumbing Services Limited | Construction | 2020 |
| Dunn Group Ltd | Wholesale & retail | 2019 |
| Duraglaze Trade Frames Ltd | Manufacturing | 2005 |
| DW Fabrications Services Ltd | Manufacturing | 2025 |
| DW Funeral Support Services Limited | Other services | 2022 |
| E & a Supplies Ltd | Wholesale & retail | 2018 |
| Eagle Sky Limited | Wholesale & retail | 2016 |
| Early Explorers Day Nursery Ltd | Health & social care | 2025 |
| Eco Swift Scaffolding (ESS) Ltd | Professional & scientific | 2024 |
| Eco Upvc Windows & Doors Limited | Construction | 2021 |
| EDEE1143 Ltd | Arts & recreation | 2018 |
| Edlight Consultant Limited | Transport & logistics | 2014 |
| Eiddo TAI Ltd | Real estate | 2022 |
| Elegant Windows Ltd | Construction | 2012 |
| Elena Coatings Limited | Construction | 2016 |
| Elephants Dont Jump Limited | Wholesale & retail | 2020 |
| Elite Holdings Group Limited | Real estate | 2024 |
| Elite Jointing Solutions Limited | Construction | 2024 |
| Elite Plumbing South Wales Limited | Construction | 2026 |
| Elite Rendering Supplies Ltd | Construction | 2017 |
| Elite Vehicle Transportation Limited | Transport & logistics | 2025 |
| Eliux Ltd | Transport & logistics | 2019 |
| Elixia Therapy Ltd | Health & social care | 2016 |
| Ema-Food Limited | Hospitality | 2013 |
| Emergency & Rescue Solutions Ltd | Professional & scientific | 2018 |
| Emph Athletic Limited | Wholesale & retail | 2026 |
| Emporium Holdings Ltd | Financial services | 2023 |
| Emrc Group Ltd | Construction | 2020 |
| END2ENDKITCHENS Ltd | Construction | 2026 |
| Energy Cert 4 U Limited | Professional & scientific | 2022 |
| ERJ Propery Limited | Real estate | 2025 |
| ERS Infrastructure Ltd | Professional & scientific | 2024 |
| ERS Investments Ltd | Households | 2023 |
| ESA (UK) Trading AS Ardakan Flat Glass Ltd. | Wholesale & retail | 2018 |
| Essential Glazing Products Ltd | Construction | 2024 |
| Eternal Hope Ltd | Arts & recreation | 2023 |
| Ethical Holidays Ltd | Hospitality | 2025 |
| Eurosource Limited | Professional & scientific | 1984 |
| Evans Vent Systems Ltd | Construction | 2015 |
| Evergreen Care Wales Limited | Health & social care | 2005 |
| Evolve Development and Project Management Services Limited | Professional & scientific | 2017 |
| Evolve Hair Studio (Caerphilly) Limited | Other services | 2019 |
| EW Bookkeeping Ltd | Administrative & support | 2016 |
| Exall Electrical Limited | Construction | 2014 |
| Excellen Consultancy Ltd | Professional & scientific | 2010 |
| Expect Groundwork Contractors Ltd | Construction | 2025 |
| Fair View 1967 Limited | Extraterritorial | 2014 |
| Falcon Fabrication and Welding Ltd | Manufacturing | 2010 |
| Family Choice ELY Property Ltd | Real estate | 2018 |
| Family Choice Fuel (Wales) Ltd | Wholesale & retail | 2015 |
| Family Choice Private Limited | Wholesale & retail | 2012 |
| Family Choice Walsall Property Ltd | Real estate | 2018 |
| FDL Consulting Ltd | Information & communication | 2010 |
| Fen's DEN Ltd | Other services | 2024 |
| Ferryman Holdings Limited | Financial services | 2023 |
| Ferryman Limited | Transport & logistics | 1991 |
| Ffions Hair and Beauty Ltd | Other services | 2018 |
| Fieldstone Transport Limited | Transport & logistics | 2025 |
| Fine Shining Limited | Administrative & support | 2020 |
| Five Star Scenery Ltd | Construction | 2026 |
| FIX IT UP Ltd | Other services | 2013 |
| Flames Kebab and Pizza (Blackwood) Ltd | Hospitality | 2018 |
| Flaxen Group Limited | Hospitality | 2016 |
| Fletchstone Enterprise Ltd | Real estate | 2024 |
| Flush Fit Installations Limited | Construction | 2023 |
| Forge Training and Consultancy Ltd | Extraterritorial | 2022 |
| Forge Your Future Training & Consultancy Ltd | Professional & scientific | 2026 |
| Four Falcons Ltd | Wholesale & retail | 2024 |
| FP Polished Decor Ltd | Manufacturing | 2020 |
| Fresh and Clean Laundry Limited | Other services | 2019 |
| Frontline Vegetation Ltd | Agriculture & fishing | 2026 |
| Furnishings Boutique Ltd | Wholesale & retail | 2025 |
| G & G Properties Management Ltd | Households | 2025 |
| G Brown and Family Funeral Directors Ltd | Other services | 2020 |
| G S Construction Service Ltd | Construction | 2014 |
| G-Fix Engineering Ltd | Manufacturing | 2016 |
| G.M.G Electrical Innovation Ltd | Energy | 2023 |
| G.W. Electrical Limited | Professional & scientific | 2003 |
| GAP Driving Services Limited | Construction | 2007 |
| GAP Wholesale Ltd | Wholesale & retail | 2022 |
| GC Enterprises (Wales) Ltd | Professional & scientific | 2007 |
| Gear Group UK Limited | Construction | 2025 |
| Gemini (CCS) Limited | Other services | 1999 |