| Embrace Your Full Potential Limited | Professional & scientific | 2022 |
| Embroidery Studio Blackpool Ltd | Wholesale & retail | 2022 |
| Embs Group NW Limited | Financial services | 2026 |
| Emea Inc Limited | Professional & scientific | 2024 |
| Emerald Horizons Specialist Cars Ltd | Administrative & support | 2025 |
| Emerald Investments Group Ltd | Real estate | 2025 |
| Emfigo Ltd | Information & communication | 2019 |
| Emilia-Olivia Limited | Health & social care | 2022 |
| Emma Louise Interior Design Limited | Professional & scientific | 2021 |
| Emma Villiers Limited | Other services | 2010 |
| Emman Solutions Limited | Information & communication | 1998 |
| Emmavies Ltd | Construction | 2025 |
| Emmy's Store Limited | Wholesale & retail | 2023 |
| Emoco Community Interest Company | Education | 2025 |
| Empathy Design Limited | Information & communication | 2015 |
| Empathy Optimal Health Ltd. | Health & social care | 2013 |
| Empire 7 Ltd | Real estate | 2024 |
| Empire Freehold Investments Ltd | Real estate | 2018 |
| Empire Inn Ltd | Hospitality | 2023 |
| Empire Italian Ltd | Other services | 2024 |
| Empire Vehicle Solutions Group Limited | Wholesale & retail | 2018 |
| Empiretex Trading Co. Limited | Wholesale & retail | 2025 |
| Employment Law Advice Limited | Professional & scientific | 2016 |
| Empower Creative Group Limited | Professional & scientific | 2025 |
| Empower Village CIC | Professional & scientific | 2025 |
| Empress Hall Ltd | Real estate | 2023 |
| Empress Property Solutions Ltd | Real estate | 2024 |
| Empro Concept Limited | Construction | 2021 |
| Emprove Fitness Ltd | Arts & recreation | 2026 |
| Emsblackpool Ltd | Administrative & support | 2017 |
| Emtc Designs Ltd | Wholesale & retail | 2025 |
| Enchanted Fabrics Ltd | Wholesale & retail | 2021 |
| Encharis Financial Consultancy Ltd | Professional & scientific | 2014 |
| Encore Yacht Ltd | Extraterritorial | 2024 |
| Endoo Limited | Information & communication | 2015 |
| Energility Limited | Wholesale & retail | 2022 |
| Energy ABC Ltd | Professional & scientific | 2013 |
| Energy Solutions Consulting Limited | Water & waste | 2019 |
| Energy Surveyors UK Limited | Professional & scientific | 2016 |
| Enexus Energy Ltd | Professional & scientific | 2021 |
| ENGAGE4BUSINESS Ltd | Wholesale & retail | 2025 |
| Engineering Performance Management Limited | Manufacturing | 2015 |
| Engraved Jewels Limited | Wholesale & retail | 2023 |
| Enhanced Media Ltd | Professional & scientific | 2023 |
| Enhancement Property Company Ltd | Real estate | 2026 |
| Enigma Electronics.Com Limited | Manufacturing | 2003 |
| Enjoy Blackpool Limited | Hospitality | 2025 |
| Enjoytech Ltd | Information & communication | 2025 |
| Ennerdaleviews Ltd | Real estate | 2023 |
| Enprin Ltd | Professional & scientific | 2021 |
| Entel Consulting Group Limited | Professional & scientific | 2002 |
| Entertainment Concepts Limited | Arts & recreation | 2015 |
| Envi Serv Ltd | Manufacturing | 2022 |
| Environmental Concept Services Limited | Wholesale & retail | 2025 |
| Environmental Northwest Ltd | Professional & scientific | 2005 |
| ENVIROSPHERE3 Limited | Water & waste | 2019 |
| Envision Housing Limited | Hospitality | 2020 |
| Envosure Limited | Construction | 2022 |
| Envy Boutique Limited | Wholesale & retail | 2025 |
| Epearl Essential Services Limited | Administrative & support | 2025 |
| EPH Property Investments Limited | Real estate | 2018 |
| Epic Surveys (NW) Limited | Professional & scientific | 2023 |
| EPM Property Ltd | Real estate | 2015 |
| Eppg Electrical Contractors Ltd | Manufacturing | 2021 |
| Eppg Plumbing Contractors Ltd | Construction | 2021 |
| Eppg Property Developers Limited | Construction | 2020 |
| Epíreia Workforce Solutions Ltd | Professional & scientific | 2024 |
| Eqms Solutions Limited | Information & communication | 2022 |
| Equilite Limited | Wholesale & retail | 2021 |
| Equilore Group Ltd | Manufacturing | 2020 |
| Equinox House Ltd | Hospitality | 2025 |
| Equinox IT Consulting Limited | Information & communication | 2010 |
| Equip Tool Hire Ltd | Administrative & support | 2010 |
| ERA LOL Holdings Limited | Financial services | 2022 |
| Erland VP Ltd | Extraterritorial | 2016 |
| ERM Developments Ltd | Real estate | 2019 |
| Eroglu Food Group Ltd | Wholesale & retail | 2026 |
| Eros-Uk Ltd | Manufacturing | 2020 |
| ERP Service Delivery Consultants Limited | Information & communication | 2015 |
| Erpasan UK Yachting Ltd | Extraterritorial | 2023 |
| Erroll Services Ltd | Information & communication | 2021 |
| Ertel Limited | Information & communication | 2022 |
| ES Businesses Ltd | Construction | 2025 |
| ES Estates (NW) Ltd | Real estate | 2025 |
| ES Law Holdings Limited | Financial services | 2018 |
| ESG Cleaning Ltd | Administrative & support | 2026 |
| Eskdale Court Management Company (Thornton) Limited | Households | 1975 |
| Esnaff Ltd | Hospitality | 2026 |
| ESO Vision Limited | Health & social care | 2026 |
| ESP MOT and Service Centre Limited | Wholesale & retail | 2018 |
| Esports Gaming Ltd | Professional & scientific | 2019 |
| Espresso Elegante Ltd | Hospitality | 2024 |
| Essex Freight Services Limited | Professional & scientific | 2001 |
| Estates Press Limited | Administrative & support | 1985 |
| ETA Technologies Ltd | Professional & scientific | 2021 |
| Etch & CUT Ltd | Arts & recreation | 2020 |
| Ethos Blackpool Ltd | Administrative & support | 2019 |
| Ethos Dental Laboratory Ltd | Health & social care | 2026 |
| Etletec Limited | Administrative & support | 2014 |
| ETM Enterprises Limited | Real estate | 2024 |