| Regain Health Limited | Health & social care | 2024 |
| Regumove Ltd | Manufacturing | 2026 |
| REK41 CIC | Health & social care | 2022 |
| Reliable Global Manufacturing Services Limited | Financial services | 2025 |
| Remyace Ltd | Wholesale & retail | 2019 |
| Renegade Surf Limited | Administrative & support | 2022 |
| Restandgo Ltd | Professional & scientific | 2025 |
| Retail Advertising Services Ltd | Manufacturing | 2013 |
| Retail Corporation Limited | Information & communication | 2004 |
| Retro Motors Trade Ltd. | Wholesale & retail | 2013 |
| Revi Civils Ltd | Construction | 2024 |
| Revo Sports Management Limited | Administrative & support | 2011 |
| Reynolds Energy Solutions Limited | Transport & logistics | 2023 |
| Reynolds Logistics NW Limited | Wholesale & retail | 2001 |
| Reynolds Logistics UK Limited | Transport & logistics | 1999 |
| RFD Limited | Manufacturing | 1950 |
| RG Developments (Wirral) Limited | Construction | 2022 |
| RH Landscapes Limited | Wholesale & retail | 2018 |
| RIA AIP Ltd | Wholesale & retail | 2025 |
| Richardsons Healthcare Limited | Manufacturing | 1988 |
| Richmond Paper Supply Company (Liverpool) Limited | Wholesale & retail | 1956 |
| Richmond Training Academy Limited | Education | 2011 |
| Ridley Street Studios Limited | Information & communication | 2025 |
| Riez Limited | Wholesale & retail | 1999 |
| Right Homes and Services Ltd | Real estate | 2026 |
| Rise & Reason Consulting Ltd | Professional & scientific | 2025 |
| Rise Young Minds Sanctuary C.I.C. | Health & social care | 2025 |
| Rismor Technologies Ltd | Information & communication | 2024 |
| Ritheesh Limited | Real estate | 2026 |
| Riverston & Wells Ltd | Real estate | 2026 |
| Rivtex Limited | Wholesale & retail | 1988 |
| RJ Stanhope Limited | Wholesale & retail | 2020 |
| RJC Training Limited Limited | Education | 2023 |
| Rldp Limited | Health & social care | 2010 |
| RNA Finance Consultants Ltd | Real estate | 2021 |
| Roadpod Ltd | Wholesale & retail | 2018 |
| Roar Clothing Limited | Wholesale & retail | 2025 |
| Robert S Boys Ltd | Professional & scientific | 2010 |
| Robertson Fairclough Ltd | Real estate | 2025 |
| Robins Property Ltd | Real estate | 2026 |
| Rock Ferry Barbershop Limited | Other services | 2020 |
| Rock Ferry Car Wash Ltd | Administrative & support | 2025 |
| Rock Ferry Waterfront Trust | Administrative & support | 2018 |
| Rockhold Scaffolding Ltd | Construction | 2018 |
| Rodenfleet Properties Limited | Real estate | 1998 |
| Rohan Car Wash Ltd | Administrative & support | 2026 |
| Rolando Luci Limited | Wholesale & retail | 2012 |
| Roman Park Limited | Health & social care | 2014 |
| Romarcoo Ltd | Wholesale & retail | 2022 |
| Rose Tree Day Nursery Ltd | Education | 2019 |
| Rose Wind Renewable Limited | Real estate | 2025 |
| Roselands Court Management Company Limited | Households | 1997 |
| Rosendale Design Ltd | Professional & scientific | 2014 |
| Rosi Fashion Limited | Manufacturing | 2019 |
| Roslyn Studio Limited | Extraterritorial | 2022 |
| Ross & Roberts Limited | Administrative & support | 1997 |
| Routeway BUS and Coach Ltd | Transport & logistics | 2026 |
| Roxburgh Cairn Consultancy Limited | Professional & scientific | 2012 |
| Royal Flush Designs Limited | Wholesale & retail | 2021 |
| Royal Mersey Yacht Club Limited | Arts & recreation | 2021 |
| RRG Facilities Limited | Administrative & support | 2013 |
| RS Cladding Limited | Construction | 2025 |
| RS Plumbing Management Limited | Construction | 2025 |
| RS Property Group Hitt Ltd | Real estate | 2023 |
| Rspg Holdings Ltd | Real estate | 2024 |
| RT Improvements Ltd | Construction | 2018 |
| Ruan Siam 9 Thai Massage & Spa Ltd | Other services | 2025 |
| Ruched and Ready Ltd | Wholesale & retail | 2019 |
| Ruiter Ltd | Manufacturing | 2021 |
| Rullerton Construction Company Limited | Construction | 2017 |
| Rupan PUB Limited | Hospitality | 2023 |
| Rupan's Property Management Ltd | Real estate | 2024 |
| Rupans Properties Ltd | Real estate | 2023 |
| Ruppys Ltd | Hospitality | 2025 |
| Ruppys Ltd | Hospitality | 2025 |
| Rush Enterprises Limited | Information & communication | 2011 |
| Russ & Rosie Ltd | Hospitality | 2025 |
| RWL Development Projects UK Ltd | Manufacturing | 2025 |
| Ryan Brown Renovations Limited | Construction | 2025 |
| Ryan Delivers Ltd | Transport & logistics | 2025 |
| Rylands Group Limited | Real estate | 2020 |
| S & I Bricker Ltd | Health & social care | 2009 |
| S & T Properties (Northwest) Ltd | Real estate | 2019 |
| S and B PVT Ltd | Health & social care | 2016 |
| S C Hair Limited | Other services | 2008 |
| S Car Repair Centre Ltd | Wholesale & retail | 2025 |
| S White Advisors Ltd | Professional & scientific | 2025 |
| S&C Vehicle and Plant Hire Limited | Construction | 2019 |
| S&K Daily Store Ltd | Wholesale & retail | 2025 |
| S&P Lees Properties Ltd | Real estate | 2025 |
| S. Lindsay Planning Services Limited | Professional & scientific | 2001 |
| S.D. Fire Systems Limited | Construction | 1996 |
| S.J.L Rigging Limited | Construction | 2015 |
| S.R. Lewis Limited | Health & social care | 2017 |
| S13 Creative Ltd | Professional & scientific | 2026 |
| Saborcito Events Limited | Hospitality | 2025 |
| Safco Food Ltd | Hospitality | 2018 |
| Safe Property Investments NW Limited | Real estate | 2019 |
| Safeharbour West Midlands Limited | Health & social care | 2009 |
| Sage Social Consultancy Ltd | Professional & scientific | 2021 |