| Dominium Homes Ltd | Real estate | 2025 |
| Door Medic Limited | Administrative & support | 2024 |
| Dotcentric Limited | Information & communication | 2010 |
| Dovetail & Crown Ltd | Construction | 2015 |
| DR Mortgage Solutions Limited | Financial services | 2015 |
| DR T J Wickrama Ltd | Health & social care | 2009 |
| Dragon Inn 8 Limited | Hospitality | 2019 |
| Drainfix Services Limited | Water & waste | 2016 |
| Drastech Ltd | Information & communication | 2022 |
| DRD Consulting Services Limited | Professional & scientific | 2019 |
| Dreamolaton Services Limited | Information & communication | 2014 |
| Drive and Detect Ltd | Professional & scientific | 2024 |
| Drive Tech Garage Services Ltd | Wholesale & retail | 2025 |
| Drive Time Motors Ltd | Wholesale & retail | 2025 |
| DRL Rail Services Limited | Construction | 2019 |
| Drnij Ltd | Health & social care | 2023 |
| Drog-Mann Ltd | Real estate | 2024 |
| DRY Cleaning Recons Ltd | Wholesale & retail | 2021 |
| DS Pet Supplies Ltd | Wholesale & retail | 2021 |
| DSE Electrical Services Ltd | Construction | 2021 |
| DSK Details Limited | Wholesale & retail | 2023 |
| DSP Imports Limited | Wholesale & retail | 2024 |
| Duct Warehouse Limited | Extraterritorial | 2013 |
| Duncan Wealth Management Limited | Financial services | 2014 |
| Durie Brothers Ltd | Wholesale & retail | 2025 |
| Dverse Management Ltd | Professional & scientific | 2025 |
| DW Brittain Limited | Construction | 2018 |
| DWE Mechanical Services Limited | Professional & scientific | 2023 |
| DXB Ltd | Professional & scientific | 2019 |
| DXR Motors Ltd | Wholesale & retail | 2025 |
| Dynamic Computing Solutions Limited | Information & communication | 2025 |
| Dynamo Public Relations Ltd | Professional & scientific | 2024 |
| Dynan Living Ltd | Real estate | 2026 |
| Dynan Ltd | Real estate | 2026 |
| Dyslexia Clarity Limited | Education | 2024 |
| E & D General Builders Limited | Construction | 2015 |
| E & P Porter Properties Limited | Real estate | 2024 |
| E & S Investment Properties Limited | Real estate | 2025 |
| E-Tech Holdings Limited | Financial services | 2024 |
| E-Tech Southern Limited | Construction | 2008 |
| E.P.H.D Services Ltd | Construction | 2022 |
| E.Z. Feeda Limited | Manufacturing | 1999 |
| Eagle Club Golf Ltd | Arts & recreation | 2025 |
| Eaglesure Insurance Services Limited | Extraterritorial | 2019 |
| Easi Ltd | Administrative & support | 2023 |
| Easiglaze Windows and Doors Limited | Construction | 2009 |
| Easter Island Limited | Wholesale & retail | 2021 |
| EAT Beef & Deadlift Limited | Education | 2022 |
| Eating Disorders Homecare Ltd | Health & social care | 2021 |
| Eaton Express Ltd | Transport & logistics | 2022 |
| Eausome Limited | Manufacturing | 2025 |
| ECB Drainage & Pest Control Services Ltd | Administrative & support | 2021 |
| Eclipse Civil Engineering Limited | Construction | 2021 |
| Eclipse Construction Ltd | Construction | 2017 |
| Eclipse Developments Limited | Construction | 2021 |
| Eclipse Group Limited | Financial services | 2021 |
| Eclipse Landscapes (E-Scapes) Limited | Professional & scientific | 2021 |
| Eclipse Plant Hire Limited | Construction | 2021 |
| Eclo North London Ltd | Education | 2022 |
| Eco Data Centres Limited | Construction | 2022 |
| Ecoflip Limited | Professional & scientific | 2024 |
| Ecogreen Electrical Ltd | Energy | 2023 |
| ECW EAR Cleaning Ltd | Health & social care | 2025 |
| Edeo Ventures Limited | Wholesale & retail | 2025 |
| Editbox Ltd | Information & communication | 2012 |
| Edith & LOU Ltd | Wholesale & retail | 2022 |
| Edjtech Ltd | Professional & scientific | 2023 |
| EDM Associates (Essex) Ltd | Professional & scientific | 2024 |
| EDP Enterprises Ltd | Professional & scientific | 2015 |
| EDU Intelligence Ltd | Extraterritorial | 2024 |
| Eduspaces (Essex) Limited | Professional & scientific | 2025 |
| Edward Charles Consulting Limited | Real estate | 2022 |
| Edward Charles Investments Limited | Real estate | 2015 |
| Edward Charles Real Estate Limited | Real estate | 2016 |
| Edward Charles Residential Investments Limited | Real estate | 2019 |
| Efme Holdings Limited | Financial services | 2024 |
| Eggz Earplugs Limited | Financial services | 2018 |
| EH Maintenance Company Ltd | Other services | 2022 |
| EHB International Ltd | Professional & scientific | 2022 |
| Eight Four Projects Ltd | Professional & scientific | 2026 |
| Eileen Estates Limited | Real estate | 2016 |
| Eithne Staunton Consultancy and Training Ltd | Health & social care | 2022 |
| EJG Surveying Limited | Professional & scientific | 2011 |
| Ejhm Properties Limited | Real estate | 2023 |
| EK Ratna Limited | Real estate | 2026 |
| Elasticad Limited | Information & communication | 2008 |
| Elastomer Trading Limited | Professional & scientific | 2006 |
| ELC Securities Limited | Transport & logistics | 2010 |
| Elco Construction Ltd | Construction | 2022 |
| Elco Scaffolding Limited | Construction | 2015 |
| Elect-Ron UK Solutions Limited | Construction | 2025 |
| Electgas Ltd | Construction | 2021 |
| Electric Snake Tattoo Ltd | Other services | 2021 |
| Electrical & Plumbing Specialist Ltd | Construction | 2026 |
| Electrifix Ltd | Construction | 2018 |
| Electronics Shack Ltd | Manufacturing | 2025 |
| Elevation 11 Limited | Other services | 2025 |
| Elite Building Contractors Ltd | Construction | 2024 |
| Elite Excavations Ltd | Administrative & support | 2006 |
| Elite Fittness Limited | Arts & recreation | 2022 |