| Redefine.Earth Ltd | Professional & scientific | 2022 |
| Redline Welding Ltd | Manufacturing | 2019 |
| Redolent Films Ltd | Information & communication | 2013 |
| Refill Studio Ltd | Information & communication | 2024 |
| Regent Carpentry Limited | Construction | 2019 |
| Remedy Records Limited | Information & communication | 2008 |
| Remgo Limited | Hospitality | 2023 |
| Renovation Homes Limited | Construction | 2022 |
| Reon-Eco Limited | Extraterritorial | 2015 |
| REVERBER8 Ltd | Arts & recreation | 2025 |
| RGJ Developments LLP | | 2026 |
| Richard Shuttleworth Trustees | Professional & scientific | 1992 |
| Richard Wright Films Limited | Information & communication | 2015 |
| Ride Europe Ltd | Administrative & support | 2026 |
| Riesgo Consultants Limited | Professional & scientific | 2017 |
| Ristorante L'Olivo Ltd | Hospitality | 2024 |
| RJG Global Consulting Ltd | Manufacturing | 2023 |
| RJT Window & Exterior Cleaning Ltd | Administrative & support | 2019 |
| RMC Property Maintenance & Landscape Limited | Construction | 2025 |
| Robin Harris Joinery Limited | Construction | 2013 |
| Rochlin Productions Ltd | Construction | 2012 |
| Rodgers Decorating Services (London) Ltd | Construction | 2019 |
| Rokz Plumbing and Heating Services Ltd | Construction | 2023 |
| Rookery Films Limited | Arts & recreation | 2016 |
| Roots-Uk Ltd | Manufacturing | 2024 |
| Ropeweaver Business Systems Ltd | Information & communication | 2011 |
| Rose Cottage Sleaford Limited | Extraterritorial | 2015 |
| Rosebud Nanny Agency Ltd | Administrative & support | 2013 |
| Rosewood Irrigation & Living Walls Ltd | Administrative & support | 2011 |
| Rosewood Living Walls Ltd | Administrative & support | 2019 |
| Rosewood Weddings & Events Ltd | Administrative & support | 2018 |
| Rosie Cheek (London) Ltd | Information & communication | 2013 |
| Rotate UK Ltd | Transport & logistics | 2013 |
| Rowan Lodge Limited | Real estate | 2024 |
| Rowan Lodge Properties Limited | Real estate | 2018 |
| RS Machinery Ltd | Administrative & support | 2010 |
| Rubberpro Technologies Ltd | Wholesale & retail | 2023 |
| Ruby Riley Ltd | Arts & recreation | 2023 |
| RUG Candy Ltd | Wholesale & retail | 2019 |
| Run Riot Apparel Ltd | Wholesale & retail | 2024 |
| Russell Bath & SON LLP | | 2025 |
| RW Warehousing & Transport Limited | Transport & logistics | 2019 |
| S & T Tunnard Ltd | Real estate | 2024 |
| S a V Logistics Ltd | Transport & logistics | 2014 |
| S D Wiseman Ltd | Information & communication | 2018 |
| S G Installations (Biggleswade) Limited | Construction | 2012 |
| S J Wilson Consulting Limited | Professional & scientific | 2016 |
| S O Developments Limited | Real estate | 2015 |
| S R K Plumbing and Heating Ltd | Construction | 2021 |
| S&Sons Properties Ltd | Real estate | 2025 |
| S.I Design & Build Ltd | Construction | 2025 |
| S.J.B. Properties Limited | Real estate | 1980 |
| Safe Hands Care Agency Limited | Health & social care | 2022 |
| Safe Hands Healthcare Services Ltd | Health & social care | 2026 |
| Safety and Wellbeing Connections Ltd | Professional & scientific | 2019 |
| Sales Engine Ltd | Professional & scientific | 2008 |
| Salus Composite Fire Doors Limited | Wholesale & retail | 2025 |
| Salva Films Limited | Information & communication | 2010 |
| Samad Technologies Limited | Financial services | 2013 |
| Sandhills Primary Care Network Ltd | Health & social care | 2024 |
| Sandra Lady Barber Ltd | Other services | 2025 |
| Sandy Gadget Repairs Limited | Manufacturing | 2021 |
| Sandyacres Management Company Limited | Households | 2018 |
| Sandygate Enterprises Limited | Real estate | 1998 |
| Santec Service Limited | Information & communication | 2021 |
| Sapphire Hair and Beauty Academy Limited | Other services | 2015 |
| SAR Home Services Ltd | Administrative & support | 2024 |
| Sara Pascoe Limited | Arts & recreation | 2018 |
| Sarah Perkins Accountancy Services Limited | Professional & scientific | 2012 |
| SAS Corp Ltd | Hospitality | 2023 |
| Savage & Sons (Electrical) Limited | Construction | 1980 |
| SAVE071713 Limited | Wholesale & retail | 2015 |
| SAZ Food Ltd | Hospitality | 2023 |
| SB Carpentry & Construction Ltd | Manufacturing | 2022 |
| Sbond Agency Limited | Wholesale & retail | 2021 |
| Scene-It Ltd | Manufacturing | 2024 |
| Sciet Health Ltd. | Professional & scientific | 2016 |
| Scout Security and Electrical Ltd | Construction | 2022 |
| Scribe Carpentry & Building Services Ltd | Construction | 2015 |
| Scrubzey Ltd | Manufacturing | 2023 |
| Scruffs Services Ltd | Other services | 2024 |
| Scurfield & Long Ltd. | Construction | 2018 |
| SDT Electrical Projects Limited | Construction | 2022 |
| Sea&Mew Warehouse UK Ltd | Professional & scientific | 2021 |
| Seconda Investments Ltd | Real estate | 2014 |
| Sector Scaffolding Services Ltd | Construction | 2020 |
| Secure Britain | Education | 2023 |
| Secure I.T. Environments Enterprise Ltd | Real estate | 2019 |
| Secure IT Electrical Limited | Extraterritorial | 2014 |
| Secure IT Environments Limited | Information & communication | 2003 |
| Seed to Feed Microfarm Limited | Agriculture & fishing | 2018 |
| Seedlab Creative Ltd | Arts & recreation | 2026 |
| Semars Ltd | Health & social care | 2022 |
| Semeestar Ltd | Professional & scientific | 2016 |
| Semicap Analytics Limited | Professional & scientific | 2022 |
| Sensys Limited | Water & waste | 1999 |
| Seward Engineering Limited | Agriculture & fishing | 1999 |
| SF Environmental Consultancy Ltd | Professional & scientific | 2025 |
| SG IT Systems UK Ltd | Information & communication | 2025 |
| SGM Atlantic Cost Managers Ltd | Construction | 2023 |