| West END Precision Limited | Manufacturing | 1979 |
| West ICA Services Ltd | Construction | 2023 |
| West Quay Distillery Ltd | Manufacturing | 2019 |
| West Tosberry Water Services Ltd | Water & waste | 2022 |
| Westcountry Ltd | Construction | 2014 |
| Westcountry Nurseries (North Devon) Limited | Agriculture & fishing | 2016 |
| Westcountry Plumbers & Builders Ltd | Wholesale & retail | 2015 |
| Westcountry Property Management Ltd | Real estate | 2013 |
| Westcountry Water Solutions Ltd | Professional & scientific | 2026 |
| Western Twoways Limited | Financial services | 1973 |
| Westview Management (Devon) Limited | Professional & scientific | 2017 |
| Westward Leisure Limited | Manufacturing | 2005 |
| Westward Living Limited | Construction | 2009 |
| White FOX Developments Ltd | Construction | 2022 |
| White House Close Limited | Extraterritorial | 2015 |
| White Property Management (North Devon) Limited | Real estate | 2026 |
| Whiteland Engineering Limited | Manufacturing | 1956 |
| Whiteland Engineering Software Ltd | Information & communication | 2009 |
| Whiteland Properties Ltd | Real estate | 2024 |
| Whitewater Cottages Ltd | Hospitality | 2018 |
| Wicked Dragon Ltd | Wholesale & retail | 2019 |
| Wide Valley Engineering Limited | Manufacturing | 2015 |
| Wilkinson Electrical Contractors Ltd | Construction | 2025 |
| Will Urquhart Ltd | Agriculture & fishing | 2006 |
| Wilson Quality Homes Limited | Construction | 2021 |
| Wimec Limited | Manufacturing | 2022 |
| WIN the Waves Limited | Administrative & support | 2025 |
| Window Doctor (South West) Ltd | Construction | 2023 |
| Wings South West | Education | 2000 |
| Winslade Holdings Limited | Financial services | 2021 |
| Winson Group Holdings Ltd | Financial services | 2022 |
| Winston Environment Control Sevices Limited | Professional & scientific | 2025 |
| Withecombe Electrical Limited | Professional & scientific | 2014 |
| Wizard Signs Ltd | Manufacturing | 2015 |
| WJL Groundworks & Grab Hire Limited | Administrative & support | 2026 |
| WLC Electrical Services Ltd | Construction | 2024 |
| Woodcraft Designs (South West) Ltd | Manufacturing | 2019 |
| Woodedit Ltd | Manufacturing | 2018 |
| Woolhart Ltd | Professional & scientific | 2013 |
| World Class Adventures Ltd | Administrative & support | 2019 |
| WOW! Creative Services Limited | Professional & scientific | 2007 |
| WR Moore & Sons Ltd | Agriculture & fishing | 2012 |
| Wrenshaws Limited | Wholesale & retail | 2006 |
| Wrights Management Limited | Administrative & support | 2023 |
| Ximo Limited | Water & waste | 2023 |
| Y 1268 Limited | Hospitality | 2014 |
| Yarde GAS Limited | Professional & scientific | 2019 |
| YEO Vale Farm Limited | Agriculture & fishing | 2008 |
| Your Choice Assisted Living Limited | Other services | 2014 |
| Your Safety Advisor Ltd | Professional & scientific | 2019 |
| Yumee 888 Limited | Hospitality | 2024 |
| Z&H Holiday FUN Club LLP | | 2021 |
| ZEN Combat School Ltd | Arts & recreation | 2022 |
| ZEN Security Services Ltd | Other services | 2019 |
| ZEN Waters C.I.C. | Health & social care | 2024 |
| ZIP Panelling Ltd | Other services | 2016 |
| ZU Blow Consultancy Limited | Administrative & support | 2016 |
| Zymax International Limited | Manufacturing | 1993 |