| Michael Cowell Construction Ltd | Construction | 2004 |
| Michelle Fleet Property Studio Ltd | Real estate | 2025 |
| Micra Ltd | Information & communication | 2025 |
| Milford Hawley Limited | Professional & scientific | 2018 |
| Mill Aquia Leisure Limited | Construction | 2013 |
| Millbrook Dairy Company Ltd | Wholesale & retail | 2018 |
| Millbrook Dairy Holding Ltd | Financial services | 2023 |
| Mills Engineering Limited | Professional & scientific | 2020 |
| Millwheel Enterprises Limited | Hospitality | 2009 |
| Mitchell and Dickinson Limited | Construction | 2010 |
| Mjaj Consultancy Ltd | Professional & scientific | 2014 |
| MK Dental Surgeries Ltd | Other services | 2024 |
| MK Oral Designs Limited | Health & social care | 2009 |
| MLS Carpentry and Construction LLP | | 2019 |
| Modi Consultants Ltd | Professional & scientific | 2020 |
| Molton's South West Limited | Hospitality | 2011 |
| Monarch Homes (SW) Ltd | Construction | 2024 |
| Monkleigh Garage LLP | | 2018 |
| Moorbe Holdings Ltd | Financial services | 2023 |
| Moors & More Ltd | Households | 2023 |
| Moran's (Devon) Limited | Hospitality | 2011 |
| Moreton House Devon Limited | Hospitality | 2014 |
| Moreton Park Retail Ltd | Wholesale & retail | 2019 |
| Morris & Bott Limited | Real estate | 2014 |
| Morris Domains Limited | Financial services | 2014 |
| Morris Shapland Financial Services Limited | Administrative & support | 2011 |
| Morse Key Limited | Professional & scientific | 2016 |
| Mother Clucking Farm Ltd | Agriculture & fishing | 2025 |
| Movegrant Property Management Limited | Hospitality | 2000 |
| Movimus Developments Limited | Professional & scientific | 2022 |
| MR HO Hot Food Limited | Hospitality | 2020 |
| MS Auto Repairs (Bideford) Limited | Wholesale & retail | 2014 |
| MS Complete Construction Ltd | Construction | 2025 |
| MS Home Improvements Ltd | Construction | 2025 |
| MSP Visual Ltd | Professional & scientific | 2023 |
| MST Developments Limited | Construction | 2018 |
| Mulberry Contract Furniture Ltd | Manufacturing | 2020 |
| Mulholland Care Ltd | Other services | 2012 |
| MXB Devon Operations Limited | Hospitality | 2015 |
| My Height IS Ltd | Information & communication | 2023 |
| Myriad Creative Industries Limited | Arts & recreation | 2024 |
| Myriad Creative Limited | Arts & recreation | 2002 |
| Myta BIO Ltd | Professional & scientific | 2025 |
| Mywestbeach Ltd | Households | 2019 |
| N & D Construction Limited | Construction | 2025 |
| Naked Salon and Studio Limited | Hospitality | 2025 |
| Naomi Kate EAR Care Ltd | Health & social care | 2026 |
| National Compensation Ltd | Professional & scientific | 2021 |
| Nature Dictates Limited | Professional & scientific | 2020 |
| Nature's Curators Ltd | Agriculture & fishing | 2018 |
| Natures Own Pets Ltd | Administrative & support | 2008 |
| NBA Spedition Ltd | Transport & logistics | 2025 |
| Neil Nicholls Plumbing & Heating Limited | Construction | 2013 |
| Nellies Nibbles Dog Larder Ltd | Wholesale & retail | 2024 |
| Nelson Birch & Sons Ltd | Construction | 2009 |
| Netizine Ltd | Information & communication | 2019 |
| Netsuper Limited | Real estate | 1997 |
| Network Publishing Group Ltd | Information & communication | 2026 |
| New Forest Houses Limited | Construction | 2013 |
| New Pizza Time Ltd | Hospitality | 2026 |
| New Tone Limited | Manufacturing | 2019 |
| New Voice Publishing Ltd | Information & communication | 2022 |
| New Wave Components, LLC | | 2008 |
| Newquay Lighthouse Project CIC | Hospitality | 2021 |
| Newynn Court Management Company Limited | Households | 2011 |
| Next Steps Education Ltd | Education | 2023 |
| Next Steps Tutors C.I.C. | Education | 2025 |
| NFH Group Limited | Financial services | 2019 |
| NG Homes SW Ltd | Construction | 2019 |
| NG Homes Tadworthy Ltd | Construction | 2019 |
| NG Properties SW Limited | Construction | 2017 |
| NGD Construction (SW) Limited | Construction | 2024 |
| NGD Homes Limited | Construction | 2024 |
| Nick Piper Limited | Construction | 2005 |
| Nigel Richardson (North Devon) Limited | Health & social care | 2017 |
| Nightwick Management Ltd | Households | 2023 |
| Nimbus 2020 Limited | Professional & scientific | 2020 |
| Ninetoes Properties Limited | Real estate | 2017 |
| NJ Martin Windows Limited | Construction | 2002 |
| NO Mise EN Plastic C.I.C. | Professional & scientific | 2022 |
| NO.6 Taxi Ltd | Extraterritorial | 2012 |
| Noblestone Property Limited | Construction | 2024 |
| Nojuan Limited | Other services | 2019 |
| Nomad Dining Ltd | Hospitality | 2019 |
| Nomad Homes Ltd | Construction | 2018 |
| Nordic Walking North Devon LP | | 2013 |
| North Coast Restorations Limited | Wholesale & retail | 2014 |
| North Devon + | Professional & scientific | 2007 |
| North Devon Bathrooms & Heating Ltd | Construction | 2021 |
| North Devon Camper Vans Limited | Manufacturing | 2021 |
| North Devon Care Limited | Health & social care | 2022 |
| North Devon Carpentry Limited | Construction | 2016 |
| North Devon Cricket Club Limited | Arts & recreation | 2011 |
| North Devon Decorators Ltd | Construction | 2015 |
| North Devon Driveways Ltd | Construction | 2020 |
| North Devon Exterior Cleaning Ltd | Administrative & support | 2025 |
| North Devon Fishermen's Association Limited | Other services | 2007 |
| North Devon Hire & Sales Ltd | Administrative & support | 2020 |
| North Devon Homes Online Ltd | Real estate | 2017 |
| North Devon Locksmiths Limited | Extraterritorial | 2019 |