| Storm Development Projects Limited | Construction | 2017 |
| Storm Graphics Limited | Manufacturing | 1994 |
| Storm Seal Building and Roofing Limited | Construction | 2023 |
| Stormgarden Limited | Professional & scientific | 2011 |
| Storyboard Design Limited | Professional & scientific | 2025 |
| Stoxham Ltd | Construction | 2019 |
| STR8TALKING Limited | Health & social care | 2022 |
| Straightline People Ltd | Construction | 2020 |
| Straiker AI UK Limited | Information & communication | 2026 |
| Stratagrid Ltd | Construction | 2026 |
| Strategic Finance Director Limited | Professional & scientific | 2011 |
| Strategic Financial Planning (SFP) Limited | Financial services | 2007 |
| Strategic Lifestyle Planning (SLP) Limited | Financial services | 2010 |
| Strathdee Holdings Limited | Households | 2025 |
| Stratton Audley Engineering Services Limited | Manufacturing | 2003 |
| Stratton Fields Management Limited | Households | 1997 |
| Streamlined Project Management UK Ltd | Professional & scientific | 2024 |
| Strider Technologies UK Ltd | Information & communication | 2021 |
| Stroud & Wasley Electrical Ltd | Construction | 2007 |
| Stuart Batsford Limited | Administrative & support | 2004 |
| Student Jobs Ltd | Administrative & support | 2025 |
| Studental Limited | Health & social care | 2009 |
| Studio 13 Architects Limited | Professional & scientific | 2012 |
| Studio Eight Hairdressing Ltd | Other services | 2023 |
| STV Motors Limited | Wholesale & retail | 2023 |
| STW Autos Limited | Wholesale & retail | 2018 |
| Sub-Arc (Oxford) Ltd | Construction | 2003 |
| Subject II Survey Limited | Administrative & support | 1999 |
| Summer House Care Ltd | Health & social care | 2023 |
| Summerfield Dwellings Limited | Real estate | 2019 |
| Summerfield Limited | Construction | 1983 |
| Summertown Audiology Ltd | Health & social care | 2022 |
| Sun WAH Ltd | Hospitality | 2017 |
| Super Bricks Ltd | Real estate | 2018 |
| Super Fit ME Limited | Education | 2025 |
| Superhuman Nation Ltd | Health & social care | 2023 |
| Surgical Initiatives Limited | Real estate | 2002 |
| Surgical Intensive Care Management Group LLP | | 2025 |
| Sussex House Management Company (Farnham Common) Limited | Households | 1982 |
| Sussex House Seventeen RTE Company Limited | Households | 2003 |
| Sustainable Materials Engineering Limited | Professional & scientific | 2007 |
| Sutton Courtenay Tyres Limited | Wholesale & retail | 2023 |
| SVK Moto Hub Ltd | Wholesale & retail | 2025 |
| Swallowfields Self Storage Ltd | Transport & logistics | 2014 |
| Swallows Nursery & Plant Centre Limited | Agriculture & fishing | 2014 |
| Swan Lane Management (Marsh Gibbon) Limited | Households | 1995 |
| Swedishcarclinic Limited | Wholesale & retail | 2010 |
| Sweet Layers TS Ltd | Manufacturing | 2025 |
| Sweet Sounds CIC | Arts & recreation | 2026 |
| Sweet Thyme Foods Ltd | Wholesale & retail | 2019 |
| Swgscommerce Ltd | Wholesale & retail | 2026 |
| Swift Regulatory Limited | Administrative & support | 2009 |
| Swiftcare Rentals Limited | Administrative & support | 2003 |
| Switch UP Style Limited | Wholesale & retail | 2017 |
| Sycamore Court RTM Company Limited | Households | 2020 |
| Synchronicity Developments Ltd | Construction | 2010 |
| Synergy Fresh Ltd | Wholesale & retail | 2021 |
| Synergy Group Consulting Ltd | Administrative & support | 2023 |
| Synergy Retail BN Ltd | Wholesale & retail | 2024 |
| Synergy Retail FC Ltd | Wholesale & retail | 2025 |
| Synergy Retail Group Ltd | Wholesale & retail | 2022 |
| Systems, Culture & I.M.P.A.C.T. Limited | Information & communication | 2017 |
| T & N Clarke Plumbing & Heating Ltd | Construction | 2017 |
| T and P Property Ltd | Real estate | 2021 |
| T C Felix Ltd | Financial services | 2020 |
| T C J Shipping Ltd | Transport & logistics | 2022 |
| T S Design and Build Ltd | Construction | 2013 |
| T. Taylor Agricultural Contractors Limited | Construction | 1977 |
| T. Taylor Contractors Limited | Construction | 1974 |
| T.P.I.S. Services Ltd | Construction | 2018 |
| T3TRAINING Limited | Other services | 2010 |
| Tadm Properties Limited | Real estate | 2019 |
| Tailormade Garden Rooms Ltd | Manufacturing | 2025 |
| Taino Properties Ltd | Construction | 2023 |
| Takesi Limited | Real estate | 2017 |
| Takhar Property Group Ltd | Real estate | 2026 |
| TAL Entertainment Limited | Other services | 2017 |
| Talbot Comptech Ltd | Manufacturing | 2022 |
| Talent Grader Ltd | Administrative & support | 2019 |
| Talkin' About Limited | Wholesale & retail | 2018 |
| Talking Nodes Limited | Information & communication | 2001 |
| Tall Oak Contracts Ltd | Construction | 2024 |
| Tall Oak Estates Limited | Real estate | 2017 |
| Tamacoco Developments Ltd | Real estate | 2024 |
| Tamarindo Communications Ltd | Administrative & support | 2010 |
| Tambula Limited | Professional & scientific | 2019 |
| TAN Property Investments Ltd | Real estate | 2024 |
| Tang & Tang Marketing Limited | Professional & scientific | 2013 |
| Tanglin Group Limited | Construction | 2023 |
| Tanuj Chopra Agencies Ltd | Wholesale & retail | 2019 |
| Taplin Estates Limited | Professional & scientific | 2013 |
| Taplin Plant Limited | Administrative & support | 2008 |
| Tapme Services Ltd. | Administrative & support | 2015 |
| Tappin's Plumbing & Building Ltd | Construction | 2024 |
| Tariali Ltd | Real estate | 2023 |
| Taro Ltd | Real estate | 2024 |
| Taryn Jacoby Ltd | Other services | 2020 |
| Tassel and Swag (Bawtry) Limited | Wholesale & retail | 2019 |
| Tax Ninja Limited | Professional & scientific | 2020 |
| Taxiomp Ltd | Transport & logistics | 2020 |