| Dog EAT Dog World Records Limited | Manufacturing | 2020 |
| Doge MGT Ltd | Real estate | 2021 |
| Dolphin Tech Ltd | Information & communication | 2025 |
| Domiciliary Care Company Limited | Health & social care | 2023 |
| DON Enterpreneurs Limited | Health & social care | 2014 |
| Doom Holding Ltd | Professional & scientific | 2019 |
| Double TAP Socials Ltd | Professional & scientific | 2024 |
| Dough&Co Bexleyheath Limited | Hospitality | 2021 |
| DP Brogan Estates Ltd | Real estate | 2025 |
| DP Fitting Ltd | Construction | 2025 |
| DR Karishma Lakhani Ltd | Health & social care | 2024 |
| Drakar Ltd | Real estate | 2019 |
| Dravonik Ltd | Transport & logistics | 2025 |
| DRD Installation Ltd | Manufacturing | 2018 |
| Dream True Ltd | Construction | 2026 |
| Dream United Limited | Manufacturing | 2021 |
| Drewan Services Ltd | Information & communication | 2023 |
| Drifta Productions Ltd | Extraterritorial | 2014 |
| Dristor TEO Kebap Ltd | Hospitality | 2025 |
| Dskg Limited | Real estate | 2018 |
| DSW Lift Solutions UK Ltd | Construction | 2023 |
| DT Events & Exhibition Services Ltd | Construction | 2024 |
| DTI Group Ltd | Information & communication | 2022 |
| Dunbar Developments Ltd | Construction | 2024 |
| Duncan Hall Limited | Professional & scientific | 2024 |
| Dush Construction Ltd | Construction | 2026 |
| Dusk to Dawn Deliveries Limited | Transport & logistics | 2019 |
| Dutta Enterprise Ltd | Professional & scientific | 2024 |
| DW Property Maintenance (South East) Limited | Other services | 2026 |
| Dwiya Limited | Professional & scientific | 2017 |
| DX IT Limited | Information & communication | 2011 |
| DXW Consulting Ltd | Professional & scientific | 2026 |
| Dynamic Transformations Ltd | Information & communication | 2024 |
| Dynamics Innovation Ltd | Real estate | 2021 |
| Dynamicsister Limited | Administrative & support | 2024 |
| Dynamo Training Solutions Limited | Education | 2021 |
| E I M Services Ltd | Real estate | 2008 |
| E K Burger Ltd | Hospitality | 2023 |
| E-Bot Technology Ltd | Wholesale & retail | 2024 |
| E-Luks Ltd | Construction | 2017 |
| E.C.A Builders Ltd | Construction | 2012 |
| E.H. Dawson Solicitors Ltd | Professional & scientific | 2017 |
| E.S. Volt Ltd | Construction | 2025 |
| E.T Clean Homes Ltd | Other services | 2025 |
| EA Realtors Limited | Real estate | 2023 |
| Eagle Performance Development Limited | Professional & scientific | 2009 |
| Easphere Ltd | Administrative & support | 2025 |
| Eastern European Investments Limited | Real estate | 2005 |
| Eastgate Property Consult Ltd | Real estate | 2024 |
| Easybuild Services Limited | Construction | 2017 |
| Eatos SPV Limited | Real estate | 2019 |
| EB Equipment Sales Ltd | Manufacturing | 2016 |
| EB Floorscreeding Ltd | Construction | 2019 |
| Ecbc Group Ltd | Professional & scientific | 2010 |
| Ecem Bookkeeping Ltd | Professional & scientific | 2019 |
| Echo Pharma Ltd | Wholesale & retail | 2025 |
| Eclipse School of Beauty Limited | Education | 2013 |
| Eco Rendering Houses Ltd | Construction | 2018 |
| Ecollence Ltd | Professional & scientific | 2020 |
| Ecompanda Limited | Hospitality | 2020 |
| Edge Healthcare Limited | Health & social care | 2018 |
| Edlins Homes Ltd | Wholesale & retail | 2016 |
| Edmpro Ltd | Information & communication | 2016 |
| Educateur Ltd | Education | 2021 |
| Edun Enterprise Ltd | Professional & scientific | 2019 |
| Edward Alderton Theatre Limited | Arts & recreation | 2003 |
| Eemmjjvv Holding Ltd | Financial services | 2025 |
| EFE (AK) Ltd | Other services | 2023 |
| EFJ Properties Ltd | Real estate | 2022 |
| EFM (Freehold) Company Limited | Households | 2002 |
| Egan Surveying Services Limited | Professional & scientific | 2015 |
| Eganow Limited | Information & communication | 2017 |
| Eirene Services Limited | Information & communication | 2019 |
| EK Mobile Ltd | Wholesale & retail | 2023 |
| Ekom Charity Trust | Other services | 2010 |
| EL Realty Ltd | Real estate | 2023 |
| Elag Holdings Ltd | Real estate | 2017 |
| Elecron UK Limited | Construction | 2013 |
| Electric ANT Ltd | Professional & scientific | 2015 |
| Electrico Contractors Ltd | Construction | 2023 |
| Eleferio Inc Limited | Wholesale & retail | 2019 |
| Elegance Engineering Ltd | Professional & scientific | 2024 |
| Elegant Teeth Ltd | Health & social care | 2022 |
| Eleos Systems Ltd | Information & communication | 2024 |
| Elessar Labs Limited | Information & communication | 2025 |
| Elevate Perform Ltd | Arts & recreation | 2026 |
| Elite Edge Corporation Limited | Other services | 2023 |
| Elite Pro Clean Ltd | Administrative & support | 2019 |
| Elite.C Maintenance Group Ltd | Households | 2024 |
| Elite.C Property Investment Ltd | Real estate | 2020 |
| Elite.C Residence Ltd | Hospitality | 2026 |
| Elka Z Cleaning Limited | Other services | 2011 |
| Elliott Management Solutions Ltd | Real estate | 2025 |
| ELO Community Ltd | Administrative & support | 2025 |
| Elvidor Ltd | Construction | 2016 |
| Elyon Y2K Ltd Limited | Transport & logistics | 2015 |
| Emamuldeen Estates Ltd | Real estate | 2021 |
| Emanuele Pantanella LUX Limited | Administrative & support | 2012 |
| Embedded Processing Ltd | Information & communication | 2022 |
| Emenu Limited | Information & communication | 2020 |