| Red Shoes (London) Limited | Construction | 2004 |
| Red Wall Ventures Limited | Extraterritorial | 2015 |
| Redbrick Ventures LLP | | 2017 |
| Redman Howard Associates Limited | Construction | 2006 |
| Redman Howard Ltd | Construction | 2010 |
| Redsocks Property LLP | | 2018 |
| Redsocks Property Management Ltd | Real estate | 2019 |
| Rental Projects Property Management LLP | | 2021 |
| Reynolds Surveyors Limited | Real estate | 2016 |
| RIA Construction Limited | Construction | 2012 |
| RIA Homes Limited | Real estate | 2006 |
| Richards Agri Limited | Agriculture & fishing | 2020 |
| Richmain Limited | Professional & scientific | 2006 |
| Ridge Homes Limited | Real estate | 2020 |
| Ridgeway Auto Refinishers Limited | Wholesale & retail | 2003 |
| Ringlewood Limited | Construction | 2008 |
| Ripley Estates Limited | Real estate | 2016 |
| Ripley Trading Ltd | Professional & scientific | 2018 |
| RK Upvc Windows & Doors Limited | Construction | 2014 |
| RMK Art Ltd | Wholesale & retail | 2015 |
| RN Realty Ltd | Extraterritorial | 2021 |
| Robin Hood PUB Limited | Hospitality | 2003 |
| Rocketbus Limited | Professional & scientific | 2011 |
| Rodinia Capital Ltd | Real estate | 2020 |
| Roland Belgrave Vintage Photography Limited | Professional & scientific | 2010 |
| Rolo Estates Ltd | Real estate | 2018 |
| Roma the Engineer Limited | Arts & recreation | 2014 |
| Roonstar Investments Limited | Real estate | 2015 |
| Roonstar Property Management LLP | | 2021 |
| Rossnakill Limited | Real estate | 2026 |
| Rother Coastal Properties Limited | Real estate | 2006 |
| Rother Commercial Limited | Real estate | 2007 |
| Rother Developments Limited | Construction | 2002 |
| Rother Estates Limited | Real estate | 2006 |
| Rotherfield Enterprises Limited | Wholesale & retail | 2012 |
| Rotherfield Holdings Limited | Financial services | 2017 |
| Rowen Estates (Sussex) Limited | Real estate | 2014 |
| RS Southwood Builders & Maintenance Limited | Construction | 2009 |
| RSK Living LLP | | 2024 |
| Rspc Property Services Limited | Real estate | 2024 |
| Ruskin House Holdings Ltd | Financial services | 2026 |
| Russell Deane Consulting Limited | Professional & scientific | 2018 |
| RVR Build Limited | Construction | 2018 |
| S.W. Electrical (Hastings) Limited | Construction | 2009 |
| Safeguard Scaffolding Limited | Construction | 1998 |
| Saint Ace Land and Property Limited | Real estate | 2016 |
| SAK Assets LLP | | 2018 |
| SAK Estates Ltd | Real estate | 2019 |
| Saltcote Mews Limited | Households | 1987 |
| Saltwyn Limited | Real estate | 2026 |
| Salvidge & Co. Ltd | Professional & scientific | 2025 |
| Sandance Investments Ltd | Real estate | 2026 |
| Sandance Property Management LLP | | 2023 |
| Sandover Property Management Limited | Households | 2000 |
| Saramy Nova Ltd | Financial services | 2026 |
| Scott Estates Management Limited | Real estate | 2005 |
| Seaford (West View Court) Managements Limited | Households | 1999 |
| Seaton 272931 Ltd | Real estate | 2026 |
| Sector IT Solutions Limited | Information & communication | 2004 |
| Sedlescombe Electrical Ltd | Construction | 2019 |
| Senrab Family Holdings Ltd | Real estate | 2021 |
| Senrab Family Partnership LLP | | 2022 |
| Sensible Property Management (Eastbourne) Limited | Real estate | 2016 |
| SGC New Homes Limited | Extraterritorial | 2010 |
| Shammi & Sapna Radia Properties Limited | Real estate | 2015 |
| Shammi Radia and Hardik Desai Properties Limited | Real estate | 2017 |
| Sharper Associates Limited | Real estate | 2021 |
| Sharpes Holdings Ltd | Financial services | 2026 |
| Shaun Collins Developments & Home Improvements Limited | Construction | 2015 |
| Shine Therapy Centre Limited | Health & social care | 2014 |
| Silver Elephant Ltd | Professional & scientific | 2010 |
| Silversleeves Ltd | Extraterritorial | 2013 |
| Simply Garden Hastings Ltd | Wholesale & retail | 2022 |
| Siren Calling CIC | Education | 2013 |
| Sizewell Lettings Ltd | Hospitality | 2011 |
| Sky Blue Water Solutions Limited | Construction | 2019 |
| Slipstream Synthetic Lubricants Co. Limited | Manufacturing | 2024 |
| Smallburd Ltd | Wholesale & retail | 2015 |
| Smart Groundworks Limited | Construction | 2018 |
| Smesh Ltd | Real estate | 2021 |
| Smith and Humphrey Limited | Wholesale & retail | 2000 |
| Snfty Ltd | Information & communication | 2022 |
| Software Developments Limited | Professional & scientific | 1990 |
| Solara Canmore UK Limited | Real estate | 2004 |
| Solomon Trade Processing Ltd | Information & communication | 2000 |
| Solution Concepts Limited | Administrative & support | 2009 |
| Sommerly Fields Management Limited | Extraterritorial | 2011 |
| Sonny Estates Limited | Real estate | 2018 |
| Sonny's Group Limited | Other services | 2018 |
| Sorella Housing Solutions LLP | | 2016 |
| Sorella Investment Solutions Ltd | Real estate | 2015 |
| Sothy Property Holdings Limited | Real estate | 2026 |
| Soutenu Limited | Professional & scientific | 2008 |
| South Lands Investment Ltd | Real estate | 2019 |
| Southern Living (Brighton) Limited | Construction | 2010 |
| Sparkes Medical Services Limited | Health & social care | 2003 |
| Specialist Care UK Group Limited | Health & social care | 2015 |
| Speckled Wood Management Limited | Households | 2019 |
| Speedmark-Uk Ltd | Manufacturing | 2003 |
| Spencers Designs Ltd | Construction | 2005 |