| ESR Land Ltd | Real estate | 2025 |
| ESR Professionals Ltd | Professional & scientific | 2017 |
| Estate Planning Solutions Limited | Financial services | 2002 |
| Esteemed Magazine Limited | Professional & scientific | 2017 |
| Ethos Heritage CIC | Education | 2022 |
| Eton Management Company Limited | Real estate | 2010 |
| Etsol 32 Limited | Real estate | 2020 |
| Euro Continental Forwarding Limited | Transport & logistics | 2009 |
| Euro-Fit Systems Limited | Wholesale & retail | 2000 |
| Eurobeck Limited | Administrative & support | 2002 |
| Euromill Supplies Ltd | Wholesale & retail | 2009 |
| European Distributed Computing Association | Professional & scientific | 2014 |
| Evans Technical Publications Limited | Information & communication | 2011 |
| Everest IT Ltd | Information & communication | 2022 |
| Everyday Designer Ltd | Professional & scientific | 2022 |
| Everything BUT the Dog Limited | Wholesale & retail | 2019 |
| Evesham Hortico Limited | Agriculture & fishing | 2002 |
| Evolve Therapy & Wellbeing Ltd | Health & social care | 2026 |
| Evolved Cema Ltd | Administrative & support | 2025 |
| EWD Investments Limited | Real estate | 2019 |
| Excel Workwear (Beverley) Limited | Manufacturing | 2015 |
| Excelsior Legal Services Limited | Professional & scientific | 2004 |
| Exempt Properties Ltd | Real estate | 2024 |
| EXG Consulting Limited | Administrative & support | 2019 |
| Exos Asset Management Limited | Extraterritorial | 2021 |
| Expert Fire Safety Limited | Construction | 2021 |
| Expert Site Services Limited | Construction | 2017 |
| Export Catalyst Ltd | Professional & scientific | 2025 |
| Express Heating Spares Ltd | Wholesale & retail | 2005 |
| F D Bird & Sons Limited | Transport & logistics | 1999 |
| F J R Consultants Limited | Professional & scientific | 2025 |
| F.R.Kirk & SON Limited | Other services | 1964 |
| FABRIC8 Steel Ltd | Manufacturing | 1999 |
| Fabrication Concepts Ltd | Manufacturing | 2024 |
| Face to Face Safety Limited | Administrative & support | 2017 |
| Factor 50 Film Limited | Information & communication | 2020 |
| Fairzephyra Ltd | Wholesale & retail | 2025 |
| Falcon Properties Hull Ltd | Real estate | 2017 |
| Fango Ltd | Information & communication | 2017 |
| Fanstone Ltd | Administrative & support | 2017 |
| Farndale House Care & Support Services Ltd | Health & social care | 2010 |
| Fasfa Limited | Other services | 2000 |
| Fastlane Auto Garage Ltd | Wholesale & retail | 2023 |
| FCH Properties Ltd | Real estate | 2024 |
| Fdgi Limited | Professional & scientific | 2013 |
| FDO 2025 Ltd | Real estate | 2025 |
| Feedgen Limited | Professional & scientific | 2022 |
| Feetham & Sons Ltd | Construction | 2018 |
| Fenton's Wetrooms Ltd | Construction | 2019 |
| Ferguson Wells Properties Limited | Real estate | 2026 |
| Ferriby Properties Limited | Construction | 2015 |
| Ferry Farm Livery Ltd | Arts & recreation | 2013 |
| Ferryport Innovation Ltd | Manufacturing | 2018 |
| FGR Investments Limited | Other services | 2022 |
| FH Recruitment Ltd | Administrative & support | 2023 |
| Fidelis Diagnostics Limited | Health & social care | 2017 |
| Figure and Form Osteopathy Ltd | Health & social care | 2021 |
| Finance Matters Corporate Solutions Ltd | Financial services | 2011 |
| Financial Control Solutions (Hull) Ltd | Professional & scientific | 2015 |
| Finch Park Properties Limited | Real estate | 2012 |
| Finchcroft Media Limited | Information & communication | 2006 |
| Finchcroft Solutions Limited | Information & communication | 2002 |
| Finding Funding Ltd | Education | 2020 |
| Finnies Accountants Limited | Professional & scientific | 2006 |
| Finnies Ltd | Extraterritorial | 2006 |
| Fire Protection Supplies Limited | Administrative & support | 2003 |
| Firefly Facilitation Ltd | Professional & scientific | 2021 |
| First Choice Parts Ltd | Wholesale & retail | 2018 |
| First Original Music Ltd | Information & communication | 2021 |
| Fitwithfran Ltd | Administrative & support | 2021 |
| Five Star Haulage Limited | Transport & logistics | 2003 |
| Five Stars Delivery Limited | Transport & logistics | 2017 |
| FIX8 Marketing Limited | Wholesale & retail | 2023 |
| FL Cafe Limited | Hospitality | 2026 |
| Flamin’ Galah (Cherry Burton) Ltd | Hospitality | 2024 |
| Flemingate Freehold Ltd | Real estate | 2017 |
| Flemingate House Management Services Limited | Households | 2006 |
| Flemingate Ltd | Real estate | 2020 |
| Fletchers Cobblers Ltd | Other services | 2019 |
| Fleur Elizabeth Dance Supplies Limited | Wholesale & retail | 2007 |
| Flexi Space UK Limited | Administrative & support | 2019 |
| Floating Point Ltd | Information & communication | 2019 |
| Flourish Hairdressing Ltd | Other services | 2018 |
| Flowseasy Limited | Information & communication | 2019 |
| FMS Site Services Limited | Construction | 2024 |
| Focus Leadership Limited | Professional & scientific | 2022 |
| FOG Fresh Ltd | Wholesale & retail | 2020 |
| Foldyard Services (East Yorkshire) Limited | Wholesale & retail | 2014 |
| Food Technologies Ltd | Administrative & support | 2023 |
| Foot Health and Wellness Clinic Ltd | Health & social care | 2025 |
| Foremans Factory Limited | Real estate | 2009 |
| Foremans Holdings Limited | Financial services | 2020 |
| Fornax & Weeks Ltd | Professional & scientific | 2026 |
| Forrester Boyd Corporate Finance Limited | Professional & scientific | 1988 |
| Forrester Boyd Limited | Professional & scientific | 2013 |
| Fortis 1926 Ltd | Agriculture & fishing | 2026 |
| Fossca Limited | Professional & scientific | 2018 |
| Foster Farms Limited | Agriculture & fishing | 2007 |
| Foster Sales Company Limited | Manufacturing | 2002 |
| Fostering and Adoption Solutions Limited | Health & social care | 2018 |